Potential of Mycobacterium tuberculosis resuscitation-promoting factors as antigens in novel tuberculosis sub-unit vaccines
Novel vaccines are needed to control tuberculosis (TB), the bacterial infectious disease that together with malaria and HIV is worldwide responsible for high levels of morbidity and mortality. TB can result from the reactivation of an initially controlled latent infection by Mycobacterium tuberculos...
Uloženo v:
| Vydáno v: | Microbes and infection Ročník 14; číslo 1; s. 86 - 95 |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
Kidlington
Elsevier Masson SAS
2012
Elsevier |
| Témata: | |
| ISSN: | 1286-4579, 1769-714X, 1769-714X |
| On-line přístup: | Získat plný text |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
| Abstract | Novel vaccines are needed to control tuberculosis (TB), the bacterial infectious disease that together with malaria and HIV is worldwide responsible for high levels of morbidity and mortality. TB can result from the reactivation of an initially controlled latent infection by
Mycobacterium tuberculosis (
Mtb).
Mtb proteins for which a possible role in this reactivation process has been hypothesized are the five homologs of the resuscitation-promoting factor of
Micrococcus luteus, namely
Mtb Rv0867c (
rpfA), Rv1009 (
rpfB), Rv1884c (
rpfC), Rv2389c (
rpfD) and Rv2450c (
rpfE). Analysis of the immune recognition of these 5 proteins following
Mtb infection or
Mycobacterium bovis BCG vaccination of mice showed that Rv1009 (rpfB) and Rv2389c (rpfD) are the most antigenic in the tested models. We therefore selected rpfB and rpfD for testing their vaccine potential as plasmid DNA vaccines. Elevated cellular immune responses and modest but significant protection against intra-tracheal
Mtb challenge were induced by immunization with the
rpfB encoding DNA vaccine. The results indicate that rpfB is the most promising candidate of the five rpf-like proteins of
Mtb in terms of its immunogenicity and protective efficacy and warrants further analysis for inclusion as an antigen in novel TB vaccines. |
|---|---|
| AbstractList | Novel vaccines are needed to control tuberculosis (TB), the bacterial infectious disease that together with malaria and HIV is worldwide responsible for high levels of morbidity and mortality. TB can result from the reactivation of an initially controlled latent infection by Mycobacterium tuberculosis (Mtb). Mtb proteins for which a possible role in this reactivation process has been hypothesized are the five homologs of the resuscitation-promoting factor of Micrococcus luteus, namely Mtb Rv0867c (rpfA), Rv1009 (rpfB), Rv1884c (rpfC), Rv2389c (rpfD) and Rv2450c (rpfE). Analysis of the immune recognition of these 5 proteins following Mtb infection or Mycobacterium bovis BCG vaccination of mice showed that Rv1009 (rpfB) and Rv2389c (rpfD) are the most antigenic in the tested models. We therefore selected rpfB and rpfD for testing their vaccine potential as plasmid DNA vaccines. Elevated cellular immune responses and modest but significant protection against intra-tracheal Mtb challenge were induced by immunization with the rpfB encoding DNA vaccine. The results indicate that rpfB is the most promising candidate of the five rpf-like proteins of Mtb in terms of its immunogenicity and protective efficacy and warrants further analysis for inclusion as an antigen in novel TB vaccines.Novel vaccines are needed to control tuberculosis (TB), the bacterial infectious disease that together with malaria and HIV is worldwide responsible for high levels of morbidity and mortality. TB can result from the reactivation of an initially controlled latent infection by Mycobacterium tuberculosis (Mtb). Mtb proteins for which a possible role in this reactivation process has been hypothesized are the five homologs of the resuscitation-promoting factor of Micrococcus luteus, namely Mtb Rv0867c (rpfA), Rv1009 (rpfB), Rv1884c (rpfC), Rv2389c (rpfD) and Rv2450c (rpfE). Analysis of the immune recognition of these 5 proteins following Mtb infection or Mycobacterium bovis BCG vaccination of mice showed that Rv1009 (rpfB) and Rv2389c (rpfD) are the most antigenic in the tested models. We therefore selected rpfB and rpfD for testing their vaccine potential as plasmid DNA vaccines. Elevated cellular immune responses and modest but significant protection against intra-tracheal Mtb challenge were induced by immunization with the rpfB encoding DNA vaccine. The results indicate that rpfB is the most promising candidate of the five rpf-like proteins of Mtb in terms of its immunogenicity and protective efficacy and warrants further analysis for inclusion as an antigen in novel TB vaccines. Novel vaccines are needed to control tuberculosis (TB), the bacterial infectious disease that together with malaria and HIV is worldwide responsible for high levels of morbidity and mortality. TB can result from the reactivation of an initially controlled latent infection by Mycobacterium tuberculosis (Mtb). Mtb proteins for which a possible role in this reactivation process has been hypothesized are the five homologs of the resuscitation-promoting factor of Micrococcus luteus, namely Mtb Rv0867c (rpfA), Rv1009 (rpfB), Rv1884c (rpfC), Rv2389c (rpfD) and Rv2450c (rpfE). Analysis of the immune recognition of these 5 proteins following Mtb infection or Mycobacterium bovis BCG vaccination of mice showed that Rv1009 (rpfB) and Rv2389c (rpfD) are the most antigenic in the tested models. We therefore selected rpfB and rpfD for testing their vaccine potential as plasmid DNA vaccines. Elevated cellular immune responses and modest but significant protection against intra-tracheal Mtb challenge were induced by immunization with the rpfB encoding DNA vaccine. The results indicate that rpfB is the most promising candidate of the five rpf-like proteins of Mtb in terms of its immunogenicity and protective efficacy and warrants further analysis for inclusion as an antigen in novel TB vaccines. Novel vaccines are needed to control tuberculosis (TB), the bacterial infectious disease that together with malaria and HIV is worldwide responsible for high levels of morbidity and mortality. TB can result from the reactivation of an initially controlled latent infection by Mycobacterium tuberculosis ( Mtb). Mtb proteins for which a possible role in this reactivation process has been hypothesized are the five homologs of the resuscitation-promoting factor of Micrococcus luteus, namely Mtb Rv0867c ( rpfA), Rv1009 ( rpfB), Rv1884c ( rpfC), Rv2389c ( rpfD) and Rv2450c ( rpfE). Analysis of the immune recognition of these 5 proteins following Mtb infection or Mycobacterium bovis BCG vaccination of mice showed that Rv1009 (rpfB) and Rv2389c (rpfD) are the most antigenic in the tested models. We therefore selected rpfB and rpfD for testing their vaccine potential as plasmid DNA vaccines. Elevated cellular immune responses and modest but significant protection against intra-tracheal Mtb challenge were induced by immunization with the rpfB encoding DNA vaccine. The results indicate that rpfB is the most promising candidate of the five rpf-like proteins of Mtb in terms of its immunogenicity and protective efficacy and warrants further analysis for inclusion as an antigen in novel TB vaccines. |
| Author | Ottenhoff, T.H.M. Huygen, K. Aryan, E. Romano, M. Korf, H. Franken, C.L.M.C. Bruffaerts, N. |
| Author_xml | – sequence: 1 givenname: M. surname: Romano fullname: Romano, M. email: marta.romano@wiv-isp.be organization: Scientific Institute of Public Health (WIV-ISP), Scientific Service Immunology, 642 Engelandstraat, B-1180 Brussels, Belgium – sequence: 2 givenname: E. surname: Aryan fullname: Aryan, E. organization: Scientific Institute of Public Health (WIV-ISP), Scientific Service Immunology, 642 Engelandstraat, B-1180 Brussels, Belgium – sequence: 3 givenname: H. surname: Korf fullname: Korf, H. organization: Scientific Institute of Public Health (WIV-ISP), Scientific Service Immunology, 642 Engelandstraat, B-1180 Brussels, Belgium – sequence: 4 givenname: N. surname: Bruffaerts fullname: Bruffaerts, N. organization: Scientific Institute of Public Health (WIV-ISP), Scientific Service Immunology, 642 Engelandstraat, B-1180 Brussels, Belgium – sequence: 5 givenname: C.L.M.C. surname: Franken fullname: Franken, C.L.M.C. organization: Leiden University Medical Center, Dept. Infectious Diseases, Leiden, Netherlands – sequence: 6 givenname: T.H.M. surname: Ottenhoff fullname: Ottenhoff, T.H.M. organization: Leiden University Medical Center, Dept. Infectious Diseases, Leiden, Netherlands – sequence: 7 givenname: K. surname: Huygen fullname: Huygen, K. organization: Scientific Institute of Public Health (WIV-ISP), Scientific Service Immunology, 642 Engelandstraat, B-1180 Brussels, Belgium |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25416873$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/21920450$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNkk1rFTEUhoNUbHv1H4jMRnQzYzL5mrgQpNQPaNGFgruQmzkpucwkNclcKP75ptxbpV20Qsg5ged9OeS8x-ggxAAIvSS4I5iId5tu9tYH1_WYkA4PXS1P0BGRQrWSsF8Hte8H0TIu1SE6znmDMeFSsGfosCeqx4zjI_TneywQijdTE11zfmXj2tgCyS9zU5Y1JLtMMfvcJMhLtr6Y4mNoL1OcY_HhonEVjyk3pp7qcwEhNz40IW5huuuQl3W7BF-arbF1cMjP0VNnpgwv9nWFfn46_XHypT379vnrycez1nIxlFY6UBJGOjIFFqQYlcVccSF6perTSuoq5yi2MDpu1Dg6xZnoDaaAKTN0hd7sfOvUvxfIRc8-W5gmEyAuWSsyYMGk7P-DpJj2rF4r9PZBkkhKOR96wiv6ao8u6xlGfZn8bNKVvl1CBV7vAZOtmVwywfr8j-OMiKH6rRDbcTbFnBO4vwjB-iYTeqN3mdA3mdB40LVU2ft7sts1lmT89Jj4w04MdUFbD0nXEECoX-0T2KLH6B82uAYla9bF |
| CitedBy_id | crossref_primary_10_1016_j_vaccine_2024_02_039 crossref_primary_10_1080_14760584_2018_1406309 crossref_primary_10_7774_cevr_2014_3_2_235 crossref_primary_10_1128_CVI_00482_12 crossref_primary_10_1371_journal_pone_0181942 crossref_primary_10_3389_fcimb_2022_1047306 crossref_primary_10_1093_femspd_ftu025 crossref_primary_10_1038_s41541_023_00623_z crossref_primary_10_1038_srep37793 crossref_primary_10_1002_1873_3468_12273 crossref_primary_10_3389_fimmu_2020_557809 crossref_primary_10_3389_fimmu_2024_1457327 crossref_primary_10_1128_CVI_00250_12 crossref_primary_10_1016_j_jmhi_2013_04_002 crossref_primary_10_1016_j_btre_2025_e00886 crossref_primary_10_1080_1040841X_2017_1283485 crossref_primary_10_3389_fimmu_2023_1193058 crossref_primary_10_1016_j_tube_2015_12_008 crossref_primary_10_1093_femsre_fuz016 crossref_primary_10_3389_fimmu_2023_1238586 crossref_primary_10_1007_s00284_022_02949_8 crossref_primary_10_13181_mji_v28i3_2444 crossref_primary_10_1134_S0006297916130095 crossref_primary_10_1111_1348_0421_12326 crossref_primary_10_1371_journal_pone_0076442 crossref_primary_10_1002_eji_201445329 crossref_primary_10_1189_jlb_0912435 crossref_primary_10_1016_j_tube_2023_102464 crossref_primary_10_4103_0255_0857_174102 crossref_primary_10_3389_fmicb_2020_00407 crossref_primary_10_1038_s41385_022_00566_z crossref_primary_10_1038_s41541_024_00834_y crossref_primary_10_1007_s10096_022_04459_8 crossref_primary_10_3389_fmicb_2025_1557511 crossref_primary_10_1016_j_syapm_2021_126234 crossref_primary_10_3109_00365548_2013_871645 crossref_primary_10_1242_dmm_033175 crossref_primary_10_1186_1471_2180_14_75 crossref_primary_10_3390_ijms22147535 crossref_primary_10_1016_j_ijtb_2019_04_012 crossref_primary_10_1016_j_intimp_2022_108791 crossref_primary_10_1080_23744235_2017_1377346 crossref_primary_10_3389_fcimb_2025_1666630 crossref_primary_10_1016_j_jbiotec_2012_11_003 crossref_primary_10_3389_fcimb_2022_1079569 crossref_primary_10_1016_j_fsi_2021_01_015 crossref_primary_10_12688_f1000research_6709_1 crossref_primary_10_12688_f1000research_6709_2 crossref_primary_10_1016_j_tube_2014_06_004 crossref_primary_10_1517_14712598_2014_951630 |
| Cites_doi | 10.1128/CVI.13.2.179-186.2006 10.1016/j.micinf.2006.03.018 10.1542/peds.96.1.29 10.1128/IAI.72.1.515-526.2004 10.1186/1471-2334-7-146 10.1371/journal.ppat.1000001 10.1128/IAI.66.4.1527-1533.1998 10.4049/jimmunol.160.4.1796 10.1016/S0140-6736(95)92348-9 10.1016/j.tube.2008.08.004 10.1128/IAI.71.1.483-493.2003 10.1371/journal.pone.0005590 10.1128/IAI.73.5.3038-3043.2005 10.1002/eji.200839148 10.1111/j.1365-2958.2007.06078.x 10.1371/journal.pone.0018632 10.1001/jama.1994.03510330076038 10.1016/j.vaccine.2008.09.025 10.1046/j.1365-2958.2002.03184.x 10.1002/eji.200939518 10.1128/CVI.00111-09 10.1073/pnas.95.15.8916 10.1128/IAI.01137-06 10.1038/nm0896-893 10.1099/mic.0.037622-0 10.1111/j.1365-2958.2007.05945.x 10.1371/journal.ppat.1002063 10.1586/erv.09.87 10.1038/nrg2432 10.1006/prep.1999.1162 10.1128/IAI.67.9.4586-4593.1999 10.1172/JCI35288 10.1111/j.1574-695X.2009.00606.x 10.1128/IAI.71.8.4789-4794.2003 10.1128/IAI.69.5.3041-3047.2001 10.1128/IAI.01735-07 10.1016/S1472-9792(03)00052-0 10.4049/jimmunol.172.11.6913 10.1128/IAI.68.12.6946-6953.2000 10.1128/IAI.70.7.3681-3688.2002 10.1046/j.1365-2958.2002.03183.x 10.1128/CVI.00492-10 10.4049/jimmunol.165.11.6463 10.1128/IAI.74.5.2985-2995.2006 10.4049/jimmunol.157.8.3527 |
| ContentType | Journal Article |
| Copyright | 2011 Institut Pasteur 2015 INIST-CNRS Copyright © 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved. |
| Copyright_xml | – notice: 2011 Institut Pasteur – notice: 2015 INIST-CNRS – notice: Copyright © 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved. |
| DBID | AAYXX CITATION IQODW CGR CUY CVF ECM EIF NPM 7S9 L.6 7X8 7QL 7T5 C1K F1W H94 H95 H97 L.G |
| DOI | 10.1016/j.micinf.2011.08.011 |
| DatabaseName | CrossRef Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed AGRICOLA AGRICOLA - Academic MEDLINE - Academic Bacteriology Abstracts (Microbiology B) Immunology Abstracts Environmental Sciences and Pollution Management ASFA: Aquatic Sciences and Fisheries Abstracts AIDS and Cancer Research Abstracts Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality Aquatic Science & Fisheries Abstracts (ASFA) Professional |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) AGRICOLA AGRICOLA - Academic MEDLINE - Academic Aquatic Science & Fisheries Abstracts (ASFA) Professional Bacteriology Abstracts (Microbiology B) ASFA: Aquatic Sciences and Fisheries Abstracts AIDS and Cancer Research Abstracts Immunology Abstracts Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality Environmental Sciences and Pollution Management |
| DatabaseTitleList | MEDLINE - Academic MEDLINE AGRICOLA Aquatic Science & Fisheries Abstracts (ASFA) Professional |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Biology |
| EISSN | 1769-714X |
| EndPage | 95 |
| ExternalDocumentID | 21920450 25416873 10_1016_j_micinf_2011_08_011 S1286457911002243 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | --- --K --M .GJ .~1 0R~ 123 1B1 1RT 1~. 1~5 29M 4.4 457 4G. 53G 5RE 5VS 7-5 71M 8P~ AAAJQ AABNK AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AARKO AAXUO ABBQC ABFNM ABFRF ABJNI ABLVK ABMAC ABMZM ABXDB ABYKQ ACDAQ ACGFS ACIUM ACRLP ADBBV ADEZE ADMUD AEBSH AEFWE AEKER AENEX AFKWA AFTJW AFXIZ AGEKW AGHFR AGUBO AGYEJ AIEXJ AIKHN AITUG AJBFU AJOXV AJRQY ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ANZVX ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV CJTIS CS3 DU5 EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 FDB FEDTE FGOYB FIRID FNPLU FYGXN G-Q GBLVA HVGLF HZ~ IHE J1W KOM LCYCR LUGTX M41 MO0 N9A O-L O9- OAUVE OZT P-8 P-9 PC. Q38 R2- RIG ROL RPZ SCC SDF SDG SDP SES SEW SPCBC SSH SSI SSZ T5K Y6R ZGI ~G- 9DU AATTM AAXKI AAYWO AAYXX ABWVN ACIEU ACLOT ACRPL ACVFH ADCNI ADNMO ADVLN AEIPS AEUPX AFJKZ AFPUW AGQPQ AIGII AIIUN AKBMS AKRWK AKYEP ANKPU APXCP CITATION EFKBS ~HD AGCQF AGRNS IQODW CGR CUY CVF ECM EIF NPM 7S9 L.6 7X8 7QL 7T5 C1K F1W H94 H95 H97 L.G |
| ID | FETCH-LOGICAL-c568t-7fe97ed3d49ece76d9c059566299e76c73f568f30cedf5a9ddf95462a03e034a3 |
| ISICitedReferencesCount | 51 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000300030300011&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1286-4579 1769-714X |
| IngestDate | Tue Oct 07 08:07:29 EDT 2025 Sun Sep 28 00:03:10 EDT 2025 Sun Sep 28 09:10:58 EDT 2025 Mon Jul 21 05:47:27 EDT 2025 Mon Jul 21 09:16:22 EDT 2025 Sat Nov 29 07:03:20 EST 2025 Tue Nov 18 21:40:57 EST 2025 Fri Feb 23 02:28:57 EST 2024 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | Mycobacterium tuberculosis Vaccine development Resuscitation-promoting factor Antigen Mycobacteriales Mycobacteriaceae Bacteria Actinomycetes Vaccine Resuscitation |
| Language | English |
| License | CC BY 4.0 Copyright © 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved. |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c568t-7fe97ed3d49ece76d9c059566299e76c73f568f30cedf5a9ddf95462a03e034a3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://zenodo.org/record/3443492 |
| PMID | 21920450 |
| PQID | 1733558215 |
| PQPubID | 24069 |
| PageCount | 10 |
| ParticipantIDs | proquest_miscellaneous_918064772 proquest_miscellaneous_913032430 proquest_miscellaneous_1733558215 pubmed_primary_21920450 pascalfrancis_primary_25416873 crossref_primary_10_1016_j_micinf_2011_08_011 crossref_citationtrail_10_1016_j_micinf_2011_08_011 elsevier_sciencedirect_doi_10_1016_j_micinf_2011_08_011 |
| PublicationCentury | 2000 |
| PublicationDate | 2012 2012-01-00 2012-Jan 20120101 |
| PublicationDateYYYYMMDD | 2012-01-01 |
| PublicationDate_xml | – year: 2012 text: 2012 |
| PublicationDecade | 2010 |
| PublicationPlace | Kidlington |
| PublicationPlace_xml | – name: Kidlington – name: France |
| PublicationTitle | Microbes and infection |
| PublicationTitleAlternate | Microbes Infect |
| PublicationYear | 2012 |
| Publisher | Elsevier Masson SAS Elsevier |
| Publisher_xml | – name: Elsevier Masson SAS – name: Elsevier |
| References | Kesavan, Brooks, Tufariello, Chan, Manabe (bib16) 2009; 89 Romano, Huygen (bib40) 2009; 8 Mukamolova, Turapov, Young, Kaprelyants, Kell, Young (bib12) 2002; 46 Tufariello, Jacobs, Chan (bib14) 2004; 72 Tufariello, Mi, Xu, Manabe, Kesavan, Drumm, Tanaka, Jacobs, Chan (bib17) 2006; 74 Hett, Chao, Deng, Rubin (bib38) 2008; 4 Demissie, Leyten, Abebe, Wassie, Aseffa, Abate, Fletcher, Owiafe, Hill, Brookes, Rook, Zumla, Arend, Klein, Ottenhoff, Andersen, Doherty (bib6) 2006; 13 D'Souza, Rosseels, Denis, Tanghe, De Smet, Jurion, Palfliet, Castiglioni, Vanonckelen, Wheeler, Huygen (bib27) 2002; 70 Zhu, Plikaytis, Shinnick (bib13) 2003; 83 Yeremeev, Kondratieva, Rubakova, Petrovskaya, Kazarian, Telkov, Biketov, Kaprelyants, Apt (bib22) 2003; 71 Geluk, van Meijgaarden, Franken, Drijfhout, D'Souza, Necker, Huygen, Ottenhoff (bib29) 2000; 165 Ottenhoff (bib2) 2009; 39 Commandeur, van Meijgaarden, Lin, Franken, Friggen, Drijfhout, Oftung, Korsvold, Geluk, Ottenhoff (bib39) 2011; 18 Singhal, Aliouat, Hervé, Mathys, Kiass, Creusy, Delaire, Tsenova, Fleurisse, Bertout, Camacho, Foo, Tay, Siew, Boukhouchi, Romano, Mathema, Dartois, Kaplan, Bifani (bib45) 2011; 6 Korf, Vander Beken, Romano, Steffensen, Stijlemans, Gustafsson, Grooten, Huygen (bib35) 2009; 119 Hett, Chao, Steyn, Fortune, Deng, Rubin (bib37) 2007; 66 Snewin, Gares, Gaora, Hasan, Brown, Young (bib25) 1999; 67 Denis, Tanghe, Palfliet, Jurion, Van den Berg, Vanonckelen, Ooms, Saman, Ulmer, Content, Huygen (bib32) 1998; 66 Wakeham, Wang, Xing (bib36) 2000; 68 Romano, Rindi, Korf, Bonanni, Adnet, Jurion, Garzelli, Huygen (bib43) 2008; 26 Romano, Denis, D'Souza, Wang, Ottenhoff, Brulet, Huygen (bib33) 2004; 172 Colditz, Berkey, Mosteller, Brewer, Wilson, Burdick, Fineberg (bib4) 1995; 96 Kana, Mizrahi (bib9) 2010; 58 Gupta, Srivastava, Srivastava (bib15) 2010; 156 D'Souza, Rosseels, Romano, Tanghe, Denis, Jurion, Castiglione, Vanonckelen, Palfliet, Huygen (bib31) 2003; 71 Mukamolova, Turapov, Kazarian, Telkov, Kaprelyants, Kell, Young (bib10) 2002; 46 Kana, Gordhan, Downing, Sung, Vostroktunova, Machowski, Tsenova, Young, Kaprelyants, Kaplan, Mizrahi (bib21) 2008; 67 Huygen, Content, Denis, Montgomery, Yawman, Deck, DeWitt, Orme, Baldwin, D'Souza, Drowart, Lozes, Vandenbussche, Van Vooren, Liu, Ulmer (bib24) 1996; 2 WHO (bib1) 2010 Franken, Hiemstra, van Meijgaarden, Subronto, den Hartigh, Ottenhoff, Drijfhout (bib28) 2000; 18 Flynn, Scanga, Tanaka, Chan (bib46) 1998; 160 Leyten, Lin, Franken, Friggen, Prins, van Meijgaarden, Voskuil, Weldingh, Andersen, Schoolnik, Arend, Ottenhoff, Klein (bib7) 2006; 8 Black, Thiel, Ota, Parida, Adegbola, Boom, Dockrell, Franken, Friggen, Hill, Klein, Lalor, Mayanja, Schoolnik, Stanley, Weldingh, Kaufmann, Walzl, Ottenhoff (bib8) 2009; 16 Fine (bib5) 1995; 346 Brandt, Oettinger, Holm, Andersen, Andersen (bib30) 1996; 157 Russell-Goldman, Xu, Wang, Chan, Tufariello (bib18) 2008; 76 Kutzler, Weiner (bib41) 2008; 9 Tanghe, D'Souza, Rosseels, Denis, Ottenhoff, Dalemans, Wheeler, Huygen (bib26) 2001; 69 Bold, Banaei, Wolf, Ernst (bib44) 2011; 7 Colditz, Brewer, Berkey, Wilson, Burdick (bib3) 1994; 271 Biketov, Potapov, Ganina, Downing, Kana, Kaprelyants (bib19) 2007; 7 Maglione, Chan (bib42) 2009; 39 Schuck, Mueller, Kunitz, Neher, Hoffmann, Franken, Repsilber, Ottenhoff, Kaufmann, Jacobsen (bib23) 2009; 4 Mukamolova, Kaprelyants, Young, Young, Kell (bib11) 1998; 95 Downing, Mischenko, Shleeva, Young, Young, Kaprelyants, Apt, Mizrahi (bib20) 2005; 73 Roupie, Romano, Zhang, Korf, Lin, Franken, Ottenhoff, Klein, Huygen (bib34) 2007; 75 Colditz (10.1016/j.micinf.2011.08.011_bib4) 1995; 96 Fine (10.1016/j.micinf.2011.08.011_bib5) 1995; 346 Hett (10.1016/j.micinf.2011.08.011_bib37) 2007; 66 Demissie (10.1016/j.micinf.2011.08.011_bib6) 2006; 13 Mukamolova (10.1016/j.micinf.2011.08.011_bib12) 2002; 46 Colditz (10.1016/j.micinf.2011.08.011_bib3) 1994; 271 Biketov (10.1016/j.micinf.2011.08.011_bib19) 2007; 7 Denis (10.1016/j.micinf.2011.08.011_bib32) 1998; 66 Tanghe (10.1016/j.micinf.2011.08.011_bib26) 2001; 69 Franken (10.1016/j.micinf.2011.08.011_bib28) 2000; 18 Romano (10.1016/j.micinf.2011.08.011_bib40) 2009; 8 Bold (10.1016/j.micinf.2011.08.011_bib44) 2011; 7 Flynn (10.1016/j.micinf.2011.08.011_bib46) 1998; 160 Downing (10.1016/j.micinf.2011.08.011_bib20) 2005; 73 Kana (10.1016/j.micinf.2011.08.011_bib9) 2010; 58 Kutzler (10.1016/j.micinf.2011.08.011_bib41) 2008; 9 D'Souza (10.1016/j.micinf.2011.08.011_bib31) 2003; 71 Commandeur (10.1016/j.micinf.2011.08.011_bib39) 2011; 18 Kesavan (10.1016/j.micinf.2011.08.011_bib16) 2009; 89 Ottenhoff (10.1016/j.micinf.2011.08.011_bib2) 2009; 39 Korf (10.1016/j.micinf.2011.08.011_bib35) 2009; 119 Yeremeev (10.1016/j.micinf.2011.08.011_bib22) 2003; 71 Wakeham (10.1016/j.micinf.2011.08.011_bib36) 2000; 68 Mukamolova (10.1016/j.micinf.2011.08.011_bib10) 2002; 46 Mukamolova (10.1016/j.micinf.2011.08.011_bib11) 1998; 95 Schuck (10.1016/j.micinf.2011.08.011_bib23) 2009; 4 Kana (10.1016/j.micinf.2011.08.011_bib21) 2008; 67 Russell-Goldman (10.1016/j.micinf.2011.08.011_bib18) 2008; 76 WHO (10.1016/j.micinf.2011.08.011_bib1) 2010 Leyten (10.1016/j.micinf.2011.08.011_bib7) 2006; 8 D'Souza (10.1016/j.micinf.2011.08.011_bib27) 2002; 70 Tufariello (10.1016/j.micinf.2011.08.011_bib14) 2004; 72 Romano (10.1016/j.micinf.2011.08.011_bib43) 2008; 26 Black (10.1016/j.micinf.2011.08.011_bib8) 2009; 16 Roupie (10.1016/j.micinf.2011.08.011_bib34) 2007; 75 Snewin (10.1016/j.micinf.2011.08.011_bib25) 1999; 67 Zhu (10.1016/j.micinf.2011.08.011_bib13) 2003; 83 Romano (10.1016/j.micinf.2011.08.011_bib33) 2004; 172 Hett (10.1016/j.micinf.2011.08.011_bib38) 2008; 4 Maglione (10.1016/j.micinf.2011.08.011_bib42) 2009; 39 Tufariello (10.1016/j.micinf.2011.08.011_bib17) 2006; 74 Huygen (10.1016/j.micinf.2011.08.011_bib24) 1996; 2 Brandt (10.1016/j.micinf.2011.08.011_bib30) 1996; 157 Gupta (10.1016/j.micinf.2011.08.011_bib15) 2010; 156 Singhal (10.1016/j.micinf.2011.08.011_bib45) 2011; 6 Geluk (10.1016/j.micinf.2011.08.011_bib29) 2000; 165 |
| References_xml | – volume: 68 start-page: 6946 year: 2000 end-page: 6953 ident: bib36 article-title: Genetically determined disparate innate and adaptive cell-mediated immune responses to pulmonary publication-title: Infect. Immun. – volume: 16 start-page: 1203 year: 2009 end-page: 1212 ident: bib8 article-title: Immunogenicity of novel DosR regulon-encoded candidate antigens of publication-title: Clin. Vaccine Immunol. – volume: 9 start-page: 776 year: 2008 end-page: 788 ident: bib41 article-title: DNA vaccines: ready for prime time? publication-title: Nat. Rev. Genet. – volume: 346 start-page: 1339 year: 1995 end-page: 1345 ident: bib5 article-title: Variation in protection by BCG: implications of and for heterologous immunity publication-title: Lancet – volume: 73 start-page: 3038 year: 2005 end-page: 3043 ident: bib20 article-title: Mutants of publication-title: Infect. Immun. – volume: 18 start-page: 676 year: 2011 end-page: 683 ident: bib39 article-title: Identification of human T-cell responses to publication-title: Clin. Vaccine Immunol. – volume: 165 start-page: 6463 year: 2000 end-page: 6471 ident: bib29 article-title: Identification of major epitopes of publication-title: J. Immunol. – volume: 69 start-page: 3041 year: 2001 end-page: 3047 ident: bib26 article-title: Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting publication-title: Infect. Immun. – volume: 26 start-page: 6053 year: 2008 end-page: 6063 ident: bib43 article-title: Immunogenicity and protective efficacy of tuberculosis subunit vaccines expressing PPE44 (Rv2770c) publication-title: Vaccine – volume: 89 start-page: 17 year: 2009 end-page: 21 ident: bib16 article-title: Tuberculosis genes expressed during persistence and reactivation in the resistant rabbit model publication-title: Tuberculosis – volume: 46 start-page: 611 year: 2002 end-page: 621 ident: bib10 article-title: The publication-title: Mol. Microbiol. – volume: 71 start-page: 4789 year: 2003 end-page: 4794 ident: bib22 article-title: Proteins of the rpf family: immune cell reactivity and vaccination efficacy against tuberculosis in mice publication-title: Infect. Immun. – volume: 8 start-page: 2052 year: 2006 end-page: 2060 ident: bib7 article-title: Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of publication-title: Microbes Infect. – volume: 271 start-page: 689 year: 1994 end-page: 702 ident: bib3 article-title: Efficacy of BCG vaccine in the prevention of tuberculosis: meta-analysis of the published literature publication-title: JAMA – volume: 119 start-page: 1626 year: 2009 end-page: 1637 ident: bib35 article-title: Liver X receptors contribute to the protective immune response against publication-title: J. Clin. Invest. – volume: 76 start-page: 4269 year: 2008 end-page: 4281 ident: bib18 article-title: A publication-title: Infect. Immun. – volume: 66 start-page: 658 year: 2007 end-page: 668 ident: bib37 article-title: A partner for the resuscitation-promoting factors of publication-title: Mol. Microbiol. – volume: 70 start-page: 3681 year: 2002 end-page: 3688 ident: bib27 article-title: Improved tuberculosis DNA vaccines by formulation in cationic lipids publication-title: Infect. Immun. – volume: 18 start-page: 95 year: 2000 end-page: 99 ident: bib28 article-title: Purification of his-tagged proteins by immobilized chelate affinity chromatography: the benefits from the use of organic solvents publication-title: Protein Expr. Purif. – volume: 39 start-page: 2014 year: 2009 end-page: 2020 ident: bib2 article-title: Overcoming the global crisis: “Yes, we can”, but also for TB…? publication-title: Eur. J. Immunol. – volume: 39 start-page: 676 year: 2009 end-page: 686 ident: bib42 article-title: How B cells shape the immune response against publication-title: Eur. J. Immunol. – volume: 66 start-page: 1527 year: 1998 end-page: 1533 ident: bib32 article-title: Vaccination with plasmid DNA encoding mycobacterial antigen 85A stimulates a CD4 publication-title: Infect. Immun. – year: 2010 ident: bib1 article-title: Global Tuberculosis Control – volume: 156 start-page: 2714 year: 2010 end-page: 2722 ident: bib15 article-title: Comparative expression analysis of rpf-like genes of publication-title: Microbiology – volume: 75 start-page: 941 year: 2007 end-page: 949 ident: bib34 article-title: Immunogenicity of eight dormancy regulon-encoded proteins of publication-title: Infect. Immun. – volume: 46 start-page: 623 year: 2002 end-page: 635 ident: bib12 article-title: A family of autocrine growth factors in publication-title: Mol. Microbiol. – volume: 4 start-page: e5590 year: 2009 ident: bib23 article-title: Identification of T-cell antigens specific for latent publication-title: PLoS ONE – volume: 7 start-page: e1002063 year: 2011 ident: bib44 article-title: Suboptimal activation of antigen-specific CD4 publication-title: PLoS Pathog. – volume: 58 start-page: 39 year: 2010 end-page: 50 ident: bib9 article-title: Resuscitation-promoting factors as lytic enzymes for bacterial growth and signaling publication-title: FEMS Immunol. Med. Microbiol. – volume: 71 start-page: 483 year: 2003 end-page: 493 ident: bib31 article-title: Mapping of murine Th1 helper T-cell epitopes of mycolyl transferases Ag85A, Ag85B and Ag85C from publication-title: Infect. Immun. – volume: 13 start-page: 179 year: 2006 end-page: 186 ident: bib6 article-title: Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with publication-title: Clin. Vaccine Immunol. – volume: 67 start-page: 672 year: 2008 end-page: 684 ident: bib21 article-title: The resuscitation-promoting factors of publication-title: Mol. Microbiol. – volume: 83 start-page: 261 year: 2003 end-page: 269 ident: bib13 article-title: Resuscitation factors from mycobacteria: homologs of publication-title: Tuberculosis – volume: 67 start-page: 4586 year: 1999 end-page: 4593 ident: bib25 article-title: Assessment of immunity to mycobacterial infection with luciferase reporter constructs publication-title: Infect. Immun. – volume: 72 start-page: 515 year: 2004 end-page: 526 ident: bib14 article-title: Individual publication-title: Infect. Immun. – volume: 157 start-page: 3527 year: 1996 end-page: 3533 ident: bib30 article-title: Key epitopes on the ESAT-6 antigen recognized in mice during the recall of protective immunity to publication-title: J. Immunol. – volume: 8 start-page: 1237 year: 2009 end-page: 1250 ident: bib40 article-title: DNA vaccines against mycobacterial diseases publication-title: Expert Rev. Vaccines – volume: 74 start-page: 2985 year: 2006 end-page: 2995 ident: bib17 article-title: Deletion of the publication-title: Infect. Immun. – volume: 7 start-page: 146 year: 2007 ident: bib19 article-title: The role of resuscitation promoting factors in pathogenesis and reactivation of publication-title: BMC Infect. Dis. – volume: 160 start-page: 1796 year: 1998 end-page: 1803 ident: bib46 article-title: Effects of aminoguanidine on latent murine tuberculosis publication-title: J. Immunol. – volume: 96 start-page: 29 year: 1995 end-page: 35 ident: bib4 article-title: The efficacy of bacillus Calmette-Guérin vaccination of newborns and infants in the prevention of tuberculosis: meta-analyses of the published literature publication-title: Pediatrics – volume: 4 start-page: e1000001 year: 2008 ident: bib38 article-title: A mycobacterial enzyme essential for cell division synergizes with resuscitation-promoting factor publication-title: PLoS Pathog. – volume: 6 start-page: e18632 year: 2011 ident: bib45 article-title: Experimental tuberculosis in the Wistar rat: a model for protective immunity and control of infection publication-title: PLoS ONE – volume: 2 start-page: 893 year: 1996 end-page: 898 ident: bib24 article-title: Immunogenicity and protective efficacy of a tuberculosis DNA vaccine publication-title: Nat. Med. – volume: 172 start-page: 6913 year: 2004 end-page: 6921 ident: bib33 article-title: Induction of publication-title: J. Immunol. – volume: 95 start-page: 8916 year: 1998 end-page: 8921 ident: bib11 article-title: A bacterial cytokine publication-title: PNAS – volume: 13 start-page: 179 year: 2006 ident: 10.1016/j.micinf.2011.08.011_bib6 article-title: Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis publication-title: Clin. Vaccine Immunol. doi: 10.1128/CVI.13.2.179-186.2006 – volume: 8 start-page: 2052 year: 2006 ident: 10.1016/j.micinf.2011.08.011_bib7 article-title: Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis publication-title: Microbes Infect. doi: 10.1016/j.micinf.2006.03.018 – volume: 96 start-page: 29 year: 1995 ident: 10.1016/j.micinf.2011.08.011_bib4 article-title: The efficacy of bacillus Calmette-Guérin vaccination of newborns and infants in the prevention of tuberculosis: meta-analyses of the published literature publication-title: Pediatrics doi: 10.1542/peds.96.1.29 – volume: 72 start-page: 515 year: 2004 ident: 10.1016/j.micinf.2011.08.011_bib14 article-title: Individual Mycobacterium tuberculosis resuscitation-promoting factor homologues are dispensable for growth in vitro and in vivo publication-title: Infect. Immun. doi: 10.1128/IAI.72.1.515-526.2004 – volume: 7 start-page: 146 year: 2007 ident: 10.1016/j.micinf.2011.08.011_bib19 article-title: The role of resuscitation promoting factors in pathogenesis and reactivation of Mycobacterium tuberculosis during intra-peritoneal infection in mice publication-title: BMC Infect. Dis. doi: 10.1186/1471-2334-7-146 – volume: 4 start-page: e1000001 year: 2008 ident: 10.1016/j.micinf.2011.08.011_bib38 article-title: A mycobacterial enzyme essential for cell division synergizes with resuscitation-promoting factor publication-title: PLoS Pathog. doi: 10.1371/journal.ppat.1000001 – volume: 66 start-page: 1527 year: 1998 ident: 10.1016/j.micinf.2011.08.011_bib32 article-title: Vaccination with plasmid DNA encoding mycobacterial antigen 85A stimulates a CD4+ and CD8+ T-cell epitopic repertoire broader than that stimulated by Mycobacterium tuberculosis H37Rv infection publication-title: Infect. Immun. doi: 10.1128/IAI.66.4.1527-1533.1998 – volume: 160 start-page: 1796 year: 1998 ident: 10.1016/j.micinf.2011.08.011_bib46 article-title: Effects of aminoguanidine on latent murine tuberculosis publication-title: J. Immunol. doi: 10.4049/jimmunol.160.4.1796 – volume: 346 start-page: 1339 year: 1995 ident: 10.1016/j.micinf.2011.08.011_bib5 article-title: Variation in protection by BCG: implications of and for heterologous immunity publication-title: Lancet doi: 10.1016/S0140-6736(95)92348-9 – volume: 89 start-page: 17 year: 2009 ident: 10.1016/j.micinf.2011.08.011_bib16 article-title: Tuberculosis genes expressed during persistence and reactivation in the resistant rabbit model publication-title: Tuberculosis doi: 10.1016/j.tube.2008.08.004 – volume: 71 start-page: 483 year: 2003 ident: 10.1016/j.micinf.2011.08.011_bib31 article-title: Mapping of murine Th1 helper T-cell epitopes of mycolyl transferases Ag85A, Ag85B and Ag85C from M. tuberculosis publication-title: Infect. Immun. doi: 10.1128/IAI.71.1.483-493.2003 – volume: 4 start-page: e5590 year: 2009 ident: 10.1016/j.micinf.2011.08.011_bib23 article-title: Identification of T-cell antigens specific for latent Mycobacterium tuberculosis infection publication-title: PLoS ONE doi: 10.1371/journal.pone.0005590 – year: 2010 ident: 10.1016/j.micinf.2011.08.011_bib1 – volume: 73 start-page: 3038 year: 2005 ident: 10.1016/j.micinf.2011.08.011_bib20 article-title: Mutants of Mycobacterium tuberculosis lacking three of the five rpf-like genes are defective for growth in vivo and for resuscitation in vitro publication-title: Infect. Immun. doi: 10.1128/IAI.73.5.3038-3043.2005 – volume: 39 start-page: 676 year: 2009 ident: 10.1016/j.micinf.2011.08.011_bib42 article-title: How B cells shape the immune response against Mycobacterium tuberculosis publication-title: Eur. J. Immunol. doi: 10.1002/eji.200839148 – volume: 67 start-page: 672 year: 2008 ident: 10.1016/j.micinf.2011.08.011_bib21 article-title: The resuscitation-promoting factors of Mycobacterium tuberculosis are required for virulence and resuscitation from dormancy but are collectively dispensable for growth in vitro publication-title: Mol. Microbiol. doi: 10.1111/j.1365-2958.2007.06078.x – volume: 6 start-page: e18632 year: 2011 ident: 10.1016/j.micinf.2011.08.011_bib45 article-title: Experimental tuberculosis in the Wistar rat: a model for protective immunity and control of infection publication-title: PLoS ONE doi: 10.1371/journal.pone.0018632 – volume: 271 start-page: 689 year: 1994 ident: 10.1016/j.micinf.2011.08.011_bib3 article-title: Efficacy of BCG vaccine in the prevention of tuberculosis: meta-analysis of the published literature publication-title: JAMA doi: 10.1001/jama.1994.03510330076038 – volume: 26 start-page: 6053 year: 2008 ident: 10.1016/j.micinf.2011.08.011_bib43 article-title: Immunogenicity and protective efficacy of tuberculosis subunit vaccines expressing PPE44 (Rv2770c) publication-title: Vaccine doi: 10.1016/j.vaccine.2008.09.025 – volume: 46 start-page: 623 year: 2002 ident: 10.1016/j.micinf.2011.08.011_bib12 article-title: A family of autocrine growth factors in Mycobacterium tuberculosis publication-title: Mol. Microbiol. doi: 10.1046/j.1365-2958.2002.03184.x – volume: 39 start-page: 2014 year: 2009 ident: 10.1016/j.micinf.2011.08.011_bib2 article-title: Overcoming the global crisis: “Yes, we can”, but also for TB…? publication-title: Eur. J. Immunol. doi: 10.1002/eji.200939518 – volume: 16 start-page: 1203 year: 2009 ident: 10.1016/j.micinf.2011.08.011_bib8 article-title: Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa publication-title: Clin. Vaccine Immunol. doi: 10.1128/CVI.00111-09 – volume: 95 start-page: 8916 year: 1998 ident: 10.1016/j.micinf.2011.08.011_bib11 article-title: A bacterial cytokine publication-title: PNAS doi: 10.1073/pnas.95.15.8916 – volume: 75 start-page: 941 year: 2007 ident: 10.1016/j.micinf.2011.08.011_bib34 article-title: Immunogenicity of eight dormancy regulon-encoded proteins of Mycobacterium tuberculosis in DNA-vaccinated and tuberculosis-infected mice publication-title: Infect. Immun. doi: 10.1128/IAI.01137-06 – volume: 2 start-page: 893 year: 1996 ident: 10.1016/j.micinf.2011.08.011_bib24 article-title: Immunogenicity and protective efficacy of a tuberculosis DNA vaccine publication-title: Nat. Med. doi: 10.1038/nm0896-893 – volume: 156 start-page: 2714 year: 2010 ident: 10.1016/j.micinf.2011.08.011_bib15 article-title: Comparative expression analysis of rpf-like genes of Mycobacterium tuberculosis H37Rv under different physiological stress and growth conditions publication-title: Microbiology doi: 10.1099/mic.0.037622-0 – volume: 66 start-page: 658 year: 2007 ident: 10.1016/j.micinf.2011.08.011_bib37 article-title: A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis publication-title: Mol. Microbiol. doi: 10.1111/j.1365-2958.2007.05945.x – volume: 7 start-page: e1002063 year: 2011 ident: 10.1016/j.micinf.2011.08.011_bib44 article-title: Suboptimal activation of antigen-specific CD4+ effector cells enables persistence of M. tuberculosis in vivo publication-title: PLoS Pathog. doi: 10.1371/journal.ppat.1002063 – volume: 8 start-page: 1237 year: 2009 ident: 10.1016/j.micinf.2011.08.011_bib40 article-title: DNA vaccines against mycobacterial diseases publication-title: Expert Rev. Vaccines doi: 10.1586/erv.09.87 – volume: 9 start-page: 776 year: 2008 ident: 10.1016/j.micinf.2011.08.011_bib41 article-title: DNA vaccines: ready for prime time? publication-title: Nat. Rev. Genet. doi: 10.1038/nrg2432 – volume: 18 start-page: 95 year: 2000 ident: 10.1016/j.micinf.2011.08.011_bib28 article-title: Purification of his-tagged proteins by immobilized chelate affinity chromatography: the benefits from the use of organic solvents publication-title: Protein Expr. Purif. doi: 10.1006/prep.1999.1162 – volume: 67 start-page: 4586 year: 1999 ident: 10.1016/j.micinf.2011.08.011_bib25 article-title: Assessment of immunity to mycobacterial infection with luciferase reporter constructs publication-title: Infect. Immun. doi: 10.1128/IAI.67.9.4586-4593.1999 – volume: 119 start-page: 1626 year: 2009 ident: 10.1016/j.micinf.2011.08.011_bib35 article-title: Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice publication-title: J. Clin. Invest. doi: 10.1172/JCI35288 – volume: 58 start-page: 39 year: 2010 ident: 10.1016/j.micinf.2011.08.011_bib9 article-title: Resuscitation-promoting factors as lytic enzymes for bacterial growth and signaling publication-title: FEMS Immunol. Med. Microbiol. doi: 10.1111/j.1574-695X.2009.00606.x – volume: 71 start-page: 4789 year: 2003 ident: 10.1016/j.micinf.2011.08.011_bib22 article-title: Proteins of the rpf family: immune cell reactivity and vaccination efficacy against tuberculosis in mice publication-title: Infect. Immun. doi: 10.1128/IAI.71.8.4789-4794.2003 – volume: 69 start-page: 3041 year: 2001 ident: 10.1016/j.micinf.2011.08.011_bib26 article-title: Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting publication-title: Infect. Immun. doi: 10.1128/IAI.69.5.3041-3047.2001 – volume: 76 start-page: 4269 year: 2008 ident: 10.1016/j.micinf.2011.08.011_bib18 article-title: A Mycobacterium tuberculosis Rpf double-knockout strain exhibits profound defects in reactivation from chronic tuberculosis and innate immunity phenotypes publication-title: Infect. Immun. doi: 10.1128/IAI.01735-07 – volume: 83 start-page: 261 year: 2003 ident: 10.1016/j.micinf.2011.08.011_bib13 article-title: Resuscitation factors from mycobacteria: homologs of Micrococcus luteus proteins publication-title: Tuberculosis doi: 10.1016/S1472-9792(03)00052-0 – volume: 172 start-page: 6913 year: 2004 ident: 10.1016/j.micinf.2011.08.011_bib33 article-title: Induction of in vivo functional Db restricted cytolytic T cell activity against a putative phosphate transport receptor of M. tuberculosis publication-title: J. Immunol. doi: 10.4049/jimmunol.172.11.6913 – volume: 68 start-page: 6946 year: 2000 ident: 10.1016/j.micinf.2011.08.011_bib36 article-title: Genetically determined disparate innate and adaptive cell-mediated immune responses to pulmonary Mycobacterium bovis BCG infection in C57BL/6 and BALB/c mice publication-title: Infect. Immun. doi: 10.1128/IAI.68.12.6946-6953.2000 – volume: 70 start-page: 3681 year: 2002 ident: 10.1016/j.micinf.2011.08.011_bib27 article-title: Improved tuberculosis DNA vaccines by formulation in cationic lipids publication-title: Infect. Immun. doi: 10.1128/IAI.70.7.3681-3688.2002 – volume: 46 start-page: 611 year: 2002 ident: 10.1016/j.micinf.2011.08.011_bib10 article-title: The rpf gene of Micrococcus luteus encodes an essential secreted growth factor publication-title: Mol. Microbiol. doi: 10.1046/j.1365-2958.2002.03183.x – volume: 18 start-page: 676 year: 2011 ident: 10.1016/j.micinf.2011.08.011_bib39 article-title: Identification of human T-cell responses to Mycobacterium tuberculosis resuscitation-promoting factors in long-term latently infected individuals publication-title: Clin. Vaccine Immunol. doi: 10.1128/CVI.00492-10 – volume: 165 start-page: 6463 year: 2000 ident: 10.1016/j.micinf.2011.08.011_bib29 article-title: Identification of major epitopes of Mycobacterium tuberculosis Ag85B that are recognized by HLA-A∗0201 restricted CD8+ T cells in HLA-transgenic mice and humans publication-title: J. Immunol. doi: 10.4049/jimmunol.165.11.6463 – volume: 74 start-page: 2985 year: 2006 ident: 10.1016/j.micinf.2011.08.011_bib17 article-title: Deletion of the Mycobacterium tuberculosis resuscitation-promoting factor Rv1009 gene results in delayed reactivation from chronic tuberculosis publication-title: Infect. Immun. doi: 10.1128/IAI.74.5.2985-2995.2006 – volume: 157 start-page: 3527 year: 1996 ident: 10.1016/j.micinf.2011.08.011_bib30 article-title: Key epitopes on the ESAT-6 antigen recognized in mice during the recall of protective immunity to Mycobacterium tuberculosis publication-title: J. Immunol. doi: 10.4049/jimmunol.157.8.3527 |
| SSID | ssj0015764 |
| Score | 2.2532072 |
| Snippet | Novel vaccines are needed to control tuberculosis (TB), the bacterial infectious disease that together with malaria and HIV is worldwide responsible for high... |
| SourceID | proquest pubmed pascalfrancis crossref elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 86 |
| SubjectTerms | Animals antigens Antigens, Bacterial - genetics Antigens, Bacterial - immunology Applied microbiology Bacterial Proteins - genetics Bacterial Proteins - immunology Bacteriology BCG Vaccine - immunology Biological and medical sciences cell-mediated immunity Cytokines - genetics Cytokines - immunology Epitopes - immunology Female Fundamental and applied biological sciences. Psychology Human immunodeficiency virus Humans immune response malaria Mice Mice, Inbred BALB C Mice, Inbred C57BL Microbiology Micrococcus luteus Micrococcus luteus - genetics Micrococcus luteus - immunology Miscellaneous morbidity mortality Mycobacterium bovis Mycobacterium bovis - genetics Mycobacterium bovis - immunology Mycobacterium bovis BCG Mycobacterium tuberculosis Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - immunology plasmids proteins recombinant vaccines Resuscitation-promoting factor Th1 Cells - immunology tuberculosis Tuberculosis - immunology Tuberculosis - pathology Tuberculosis - prevention & control Tuberculosis Vaccines - genetics Tuberculosis Vaccines - immunology vaccination Vaccine development Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vaccines, DNA - genetics Vaccines, DNA - immunology |
| Title | Potential of Mycobacterium tuberculosis resuscitation-promoting factors as antigens in novel tuberculosis sub-unit vaccines |
| URI | https://dx.doi.org/10.1016/j.micinf.2011.08.011 https://www.ncbi.nlm.nih.gov/pubmed/21920450 https://www.proquest.com/docview/1733558215 https://www.proquest.com/docview/913032430 https://www.proquest.com/docview/918064772 |
| Volume | 14 |
| WOSCitedRecordID | wos000300030300011&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVESC databaseName: Elsevier SD Freedom Collection Journals 2021 customDbUrl: eissn: 1769-714X dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0015764 issn: 1286-4579 databaseCode: AIEXJ dateStart: 19990101 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1ba9swFBZpusFgjN26ZZegwd6Kh--SH72RsFuSkrWQPRlHlqAltUNsh5b9jv3fHVmWEy9k2R4GwcRGkpWcT9J3pHNB6K2VeMKae64hLGoabmBRgwKxNuZEmCa3LMFE5Sj8lYzHdDYLzjqdn9oXZr0gaUpvboLlfxU1PANhS9fZfxB30yg8gO8gdLiC2OH6V4I_ywppAaRI5uiWwYCtAjKX16dFOecrVi4yGYUE9OwS1j91FG8slVmeNKusM_DEMnpzIYN1Viazabbmi3YLeTk3SpgSTtcxk-fz-TbTHUlLvznP6_BOyuRr43Y2GYXjSWs3Npx-D8ct34gvk-mw5T_xfnoxHIaD6fm3zSFSvWNhbTRb7USzNd_a1DdcT-WTaSZkdwd4anbVQbOrG5Wbc2cFUJsRV--upWHCVozWekpvBdz-bSFszBNBabZ8SpwjdGwT0Li66Dj8NJh9bo6nQEmrzBV077VPZmU4uPvmfZzn_jLOYSQKlUJlv45TcZ3zh-hBraTgUIHrEerw9DG6q9KW3j5BPxqI4UzgFsTwNkDwHojhGmI4hk8NMXyZ4gpi7RY0xLCG2FN0MRycf_ho1Ek8DOb5tDCI4AHhiZO4AWec-EnAgNGDEgE8CG4ZcQSUE47JeCK8OEgSEXiub8emw03HjZ0T1E2zlD9HmPpM2ML1HUIZ0ChOCQ2Y6zNYJ-3EsdwecvTfHOnfJhOtLCJtyngVKeFEUjiRzL9qWT1kNLWWKsLLgfJESzCqWapinxFA8EDNfkvgzes03nrojUYAVM_l0V2c8qzMI4s4Mg8C8PMewnvKBJKO2q5j_qkIlc7lxO6hZwpgmz6AqgfqnfniUCdfontyUKttyFeoW6xK_hrdYeviMl_10RGZ0X49Xn4BZvTucg |
| linkProvider | Elsevier |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Potential+of+Mycobacterium+tuberculosis+resuscitation-promoting+factors+as+antigens+in+novel+tuberculosis+sub-unit+vaccines&rft.jtitle=Microbes+and+infection&rft.au=ROMANO%2C+M&rft.au=ARYAN%2C+E&rft.au=KORF%2C+H&rft.au=BRUFFAERTS%2C+N&rft.date=2012&rft.pub=Elsevier&rft.issn=1286-4579&rft.volume=14&rft.issue=1&rft.spage=86&rft.epage=95&rft_id=info:doi/10.1016%2Fj.micinf.2011.08.011&rft.externalDBID=n%2Fa&rft.externalDocID=25416873 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1286-4579&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1286-4579&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1286-4579&client=summon |