No laughing white matter: Reduced integrity of the cortical cholinergic pathways in Parkinson's disease-related cognitive impairment

Approximately one third of recently diagnosed Parkinson's disease (PD) patients experience cognitive decline. The nucleus basalis of Meynert (NBM) degenerates early in PD and is crucial for cognitive function. The two main NBM white matter pathways include a lateral and medial trajectory. Howev...

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Bibliographic Details
Published in:	Neurobiology of disease Vol. 185; p. 106243
Main Authors:	Crockett, Rachel A., Wilkins, Kevin B., Aditham, Sudeep, Brontë-Stewart, Helen M.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.09.2023 Elsevier
Subjects:	Cholinergic networks Cognition Cognitive Dysfunction - complications Cognitive Dysfunction - etiology Diffusion Magnetic Resonance Imaging Humans Mild cognitive impairment Neurodegenerative disease Parkinson Disease - complications Parkinson Disease - diagnostic imaging Parkinson's disease Tractography White Matter - diagnostic imaging White matter integrity Cholinergic networks Parkinson's disease Mild cognitive impairment Tractography Neurodegenerative disease Cognition White matter integrity
ISSN:	0969-9961, 1095-953X, 1095-953X
Online Access:	Get full text
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