Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients

Background Chemotherapy is extensively used to treat breast cancer and is associated with skeletal muscle deconditioning, which is known to reduce patients' quality of life, treatment efficiency, and overall survival. To date, skeletal muscle mitochondrial alterations represent a major aspect e...

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Bibliographic Details
Published in:	Journal of cachexia, sarcopenia and muscle Vol. 13; no. 3; pp. 1896 - 1907
Main Authors:	Mallard, Joris, Hucteau, Elyse, Charles, Anne‐Laure, Bender, Laura, Baeza, Claire, Pélissie, Mathilde, Trensz, Philippe, Pflumio, Carole, Kalish‐Weindling, Michal, Gény, Bernard, Schott, Roland, Favret, Fabrice, Pivot, Xavier, Hureau, Thomas J., Pagano, Allan F.
Format:	Journal Article
Language:	English
Published:	Germany John Wiley & Sons, Inc 01.06.2022 John Wiley and Sons Inc Wiley
Subjects:	Apoptosis Biopsy Biosynthesis Breast cancer Breast Neoplasms - metabolism Cancer therapies Chemotherapy Female H2O2 Homeostasis Humans Mitochondria - metabolism Mitochondrial biogenesis Mitochondrial dynamics Mitophagy Muscle, Skeletal - metabolism Musculoskeletal system Original Proteins Quality of Life Reactive oxygen species Skeletal muscle deconditioning Ubiquitin-Protein Ligases - metabolism Mitochondrial biogenesis Skeletal muscle deconditioning H2O2 Mitophagy Mitochondrial dynamics Apoptosis
ISSN:	2190-5991, 2190-6009, 2190-6009
Online Access:	Get full text
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