Comprehensive metagenomic analysis of glioblastoma reveals absence of known virus despite antiviral‐like type I interferon gene response

Glioblastoma is a deadly malignant brain tumor and one of the most incurable forms of cancer in need of new therapeutic targets. As some cancers are known to be caused by a virus, the discovery of viruses could open the possibility to treat, and perhaps prevent, such a disease. Although an associati...

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Veröffentlicht in:	International journal of cancer Jg. 135; H. 6; S. 1381 - 1389
Hauptverfasser:	Cosset, Érika, Petty, Tom J., Dutoit, Valérie, Cordey, Samuel, Padioleau, Ismael, Otten‐Hernandez, Patricia, Farinelli, Laurent, Kaiser, Laurent, Bruyère‐Cerdan, Pascale, Tirefort, Diderik, Amar El‐Dusouqui, Soraya, Nayernia, Zeynab, Krause, Karl‐Heinz, Zdobnov, Evgeny M., Dietrich, Pierre‐Yves, Rigal, Emmanuel, Preynat‐Seauve, Olivier
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Hoboken, NJ Wiley-Blackwell 15.09.2014 Wiley Subscription Services, Inc Wiley BlackWell Publishing Ltd
Schlagworte:	Antibodies, Viral - blood Antiviral drugs antiviral type I interferon response Biological and medical sciences Biopsy Brain cancer Brain Neoplasms - genetics Brain Neoplasms - immunology Brain Neoplasms - virology Brain tumors Cancer Computational neuroscience Cytomegalovirus Cytomegalovirus - immunology Genomics Glioblastoma Glioblastoma - genetics Glioblastoma - virology glioblastoma multiforme Glioma High-Throughput Nucleotide Sequencing high‐throughput sequencing Humans Immunoglobulin G - blood Immunoglobulin M - blood Infectious Causes of Cancer Interferon Interferon Type I - immunology Life Sciences Medical diagnosis Medical research Medical sciences Medical screening metagenomic analysis Metagenomics Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neurology Pathogenesis RNA viruses Simian virus 40 Targeted cancer therapy Therapeutic targets Tumors Tumors of the nervous system. Phacomatoses virus discovery Viruses Nervous system diseases Nucleotide sequence Cytokine Malignant tumor Glioblastoma multiforme Virus Malignant glioma metagenomic analysis Cancerology Gene Central nervous system disease virus discovery Antiviral Genetics Interferon antiviral type I interferon response Sequencing high-throughput sequencing Cancer glioblastoma multiforme
ISSN:	0020-7136, 1097-0215, 1097-0215
Online-Zugang:	Volltext
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