Distinguishing the immunostimulatory properties of noncoding RNAs expressed in cancer cells

Recent studies have demonstrated abundant transcription of a set of noncoding RNAs (ncRNAs) preferentially within tumors as opposed to normal tissue. Using an approach from statistical physics, we quantify global transcriptome-wide motif use for the first time, to our knowledge, in human and murine...

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Vydané v:	Proceedings of the National Academy of Sciences - PNAS Ročník 112; číslo 49; s. 15154
Hlavní autori:	Tanne, Antoine, Muniz, Luciana R, Puzio-Kuter, Anna, Leonova, Katerina I, Gudkov, Andrei V, Ting, David T, Monasson, Rémi, Cocco, Simona, Levine, Arnold J, Bhardwaj, Nina, Greenbaum, Benjamin D
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 08.12.2015
Predmet:	Animals Humans Immunity, Innate Mice Neoplasms - genetics Neoplasms - immunology RNA, Untranslated - immunology genome evolution noncoding RNA cancer immunology
ISSN:	1091-6490, 1091-6490
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