Head and neck cancer prevention: from primary prevention to impact of clinicians on reducing burden

Survival from head and neck cancers (HNCs) of the lip, oral cavity, pharynx, and larynx has increased by 10% over the past few decades. Little over half of patients who develop HNCs will survive beyond 5 years. Survival is lower for individuals in many countries where traditional risk factors such a...

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Vydané v:Annals of oncology Ročník 30; číslo 5; s. 744 - 756
Hlavní autori: Hashim, D, Genden, E, Posner, M, Hashibe, M, Boffetta, P
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: England 01.05.2019
Predmet:
Head and Neck Neoplasms - diagnosis
Head and Neck Neoplasms - pathology
Head and Neck Neoplasms - prevention & control
Healthy Lifestyle
Humans
Pathology, Molecular - methods
Practice Patterns, Physicians
Primary Prevention
Treatment Outcome
head and neck neoplasms
early detection of cancer/statistics & numerical data
mouth neoplasms/diagnosis
cancer prevention
dentists
mouth neoplasms
ISSN:1569-8041, 1569-8041
On-line prístup:Zistit podrobnosti o prístupe
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Popis
Shrnutí:Survival from head and neck cancers (HNCs) of the lip, oral cavity, pharynx, and larynx has increased by 10% over the past few decades. Little over half of patients who develop HNCs will survive beyond 5 years. Survival is lower for individuals in many countries where traditional risk factors such as tobacco smoking, alcohol drinking, and betel quid chewing are highly prevalent but tertiary health care center access is limited or unavailable. Early diagnosis of HNC is the most important prognostic factor for each tumor site. Molecular-based research on HNC tumors holds promise for early stage detection, screening, vaccination, disease follow-up, and progression. Future investments for HNC control must consider both effectiveness and sustainability for both high- and low-resource countries alike, with priority toward risk factor prevention and earlier diagnosis.
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ObjectType-Review-3
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ISSN:1569-8041
1569-8041
DOI:10.1093/annonc/mdz084