Head and neck cancer prevention: from primary prevention to impact of clinicians on reducing burden

Survival from head and neck cancers (HNCs) of the lip, oral cavity, pharynx, and larynx has increased by 10% over the past few decades. Little over half of patients who develop HNCs will survive beyond 5 years. Survival is lower for individuals in many countries where traditional risk factors such a...

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Vydáno v:	Annals of oncology Ročník 30; číslo 5; s. 744 - 756
Hlavní autoři:	Hashim, D, Genden, E, Posner, M, Hashibe, M, Boffetta, P
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England 01.05.2019
Témata:	Head and Neck Neoplasms - diagnosis Head and Neck Neoplasms - pathology Head and Neck Neoplasms - prevention & control Healthy Lifestyle Humans Pathology, Molecular - methods Practice Patterns, Physicians Primary Prevention Treatment Outcome head and neck neoplasms early detection of cancer/statistics & numerical data mouth neoplasms/diagnosis cancer prevention dentists mouth neoplasms
ISSN:	1569-8041, 1569-8041
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Abstract	Survival from head and neck cancers (HNCs) of the lip, oral cavity, pharynx, and larynx has increased by 10% over the past few decades. Little over half of patients who develop HNCs will survive beyond 5 years. Survival is lower for individuals in many countries where traditional risk factors such as tobacco smoking, alcohol drinking, and betel quid chewing are highly prevalent but tertiary health care center access is limited or unavailable. Early diagnosis of HNC is the most important prognostic factor for each tumor site. Molecular-based research on HNC tumors holds promise for early stage detection, screening, vaccination, disease follow-up, and progression. Future investments for HNC control must consider both effectiveness and sustainability for both high- and low-resource countries alike, with priority toward risk factor prevention and earlier diagnosis.
AbstractList	Survival from head and neck cancers (HNCs) of the lip, oral cavity, pharynx, and larynx has increased by 10% over the past few decades. Little over half of patients who develop HNCs will survive beyond 5 years. Survival is lower for individuals in many countries where traditional risk factors such as tobacco smoking, alcohol drinking, and betel quid chewing are highly prevalent but tertiary health care center access is limited or unavailable. Early diagnosis of HNC is the most important prognostic factor for each tumor site. Molecular-based research on HNC tumors holds promise for early stage detection, screening, vaccination, disease follow-up, and progression. Future investments for HNC control must consider both effectiveness and sustainability for both high- and low-resource countries alike, with priority toward risk factor prevention and earlier diagnosis. Survival from head and neck cancers (HNCs) of the lip, oral cavity, pharynx, and larynx has increased by 10% over the past few decades. Little over half of patients who develop HNCs will survive beyond 5 years. Survival is lower for individuals in many countries where traditional risk factors such as tobacco smoking, alcohol drinking, and betel quid chewing are highly prevalent but tertiary health care center access is limited or unavailable. Early diagnosis of HNC is the most important prognostic factor for each tumor site. Molecular-based research on HNC tumors holds promise for early stage detection, screening, vaccination, disease follow-up, and progression. Future investments for HNC control must consider both effectiveness and sustainability for both high- and low-resource countries alike, with priority toward risk factor prevention and earlier diagnosis.Survival from head and neck cancers (HNCs) of the lip, oral cavity, pharynx, and larynx has increased by 10% over the past few decades. Little over half of patients who develop HNCs will survive beyond 5 years. Survival is lower for individuals in many countries where traditional risk factors such as tobacco smoking, alcohol drinking, and betel quid chewing are highly prevalent but tertiary health care center access is limited or unavailable. Early diagnosis of HNC is the most important prognostic factor for each tumor site. Molecular-based research on HNC tumors holds promise for early stage detection, screening, vaccination, disease follow-up, and progression. Future investments for HNC control must consider both effectiveness and sustainability for both high- and low-resource countries alike, with priority toward risk factor prevention and earlier diagnosis.
Author	Posner, M Hashim, D Genden, E Boffetta, P Hashibe, M
Author_xml	– sequence: 1 givenname: D surname: Hashim fullname: Hashim, D email: dana.hashim@mssm.edu organization: Tisch Cancer Institute, Division of Hematology, Oncology, and Department of Medicine. Electronic address: dana.hashim@mssm.edu – sequence: 2 givenname: E surname: Genden fullname: Genden, E organization: Ear, Nose, Throat / Otolaryngology, Icahn School of Medicine at Mount Sinai, New York – sequence: 3 givenname: M surname: Posner fullname: Posner, M organization: Tisch Cancer Institute, Division of Hematology, Oncology, and Department of Medicine – sequence: 4 givenname: M surname: Hashibe fullname: Hashibe, M organization: Department of Family and Preventive Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, USA – sequence: 5 givenname: P surname: Boffetta fullname: Boffetta, P organization: Tisch Cancer Institute, Division of Hematology, Oncology, and Department of Medicine
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/30840052$$D View this record in MEDLINE/PubMed
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ContentType	Journal Article
Copyright	The Author(s) 2019. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oup.com.
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Keywords	head and neck neoplasms early detection of cancer/statistics & numerical data mouth neoplasms/diagnosis cancer prevention dentists mouth neoplasms
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SubjectTerms	Head and Neck Neoplasms - diagnosis Head and Neck Neoplasms - pathology Head and Neck Neoplasms - prevention & control Healthy Lifestyle Humans Pathology, Molecular - methods Practice Patterns, Physicians Primary Prevention Treatment Outcome
Title	Head and neck cancer prevention: from primary prevention to impact of clinicians on reducing burden
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