The lncRNA GAS5 upregulates ANXA2 to mediate the macrophage inflammatory response during atherosclerosis development

Inflammatory macrophages play a crucial role in atherosclerosis development. The long non-coding RNA growth arrest-specific 5 (GAS5) regulates THP-1 macrophage inflammation by sponging microRNAs. The purpose of this study was to investigate the regulatory mechanism of GAS5 in atherosclerosis develop...

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Bibliographic Details
Published in:	Heliyon Vol. 10; no. 2; p. e24103
Main Authors:	Xue, Yuzhou, Hu, Yu, Yu, Shikai, Zhu, Wenyan, Liu, Lin, Luo, Minghao, Luo, Suxin, Shen, Jian, Huang, Longxiang, Liu, Jie, Lv, Dingyi, Zhang, Wenming, Wang, Jingyu, Li, Xiang
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 30.01.2024 Elsevier
Subjects:	ANXA2 Apoptosis Atherosclerosis data collection GAS5 gene expression genes inflammation Inflammatory response low density lipoprotein Macrophage macrophage activation macrophages microRNA non-coding RNA oxidation plasmids small interfering RNA therapeutics Western blotting Inflammatory response ANXA2 GAS5 Atherosclerosis Apoptosis Macrophage
ISSN:	2405-8440, 2405-8440
Online Access:	Get full text
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