Live-cell imaging of Marburg virus-infected cells uncovers actin-dependent transport of nucleocapsids over long distances

Transport of large viral nucleocapsids from replication centers to assembly sites requires contributions from the host cytoskeleton via cellular adaptor and motor proteins. For the Marburg and Ebola viruses, related viruses that cause severe hemorrhagic fevers, the mechanism of nucleocapsid transpor...

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Bibliographic Details

Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 110; no. 35; p. 14402
Main Authors:	Schudt, Gordian, Kolesnikova, Larissa, Dolnik, Olga, Sodeik, Beate, Becker, Stephan
Format:	Journal Article
Language:	English
Published:	United States 27.08.2013
Subjects:	Actins - metabolism Cell Line Humans Marburgvirus - genetics Marburgvirus - metabolism Nucleocapsid - metabolism Protein Transport Pseudopodia - metabolism Viral Matrix Proteins - genetics Viral Matrix Proteins - metabolism viral inclusion bodies dual-color imaging reverse genetics
ISSN:	1091-6490, 1091-6490
Online Access:	Get more information
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