Protein C anticoagulant system—anti-inflammatory effects

Activated protein C (APC) plays active roles in preventing progression of a number of disease processes. These include thrombosis due to its direct anticoagulant activity which is likely augmented by its cytoprotective activity, thereby limiting exposure of procoagulant cellular membrane surfaces on...

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Bibliographic Details
Published in:	Seminars in immunopathology Vol. 34; no. 1; pp. 127 - 132
Main Author:	Esmon, Charles T.
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer-Verlag 01.01.2012 Springer Nature B.V
Subjects:	Animals Anti-Inflammatory Agents - immunology Anti-Inflammatory Agents - metabolism Anticoagulants Anticoagulants - immunology Anticoagulants - metabolism Antigens, CD - biosynthesis Antigens, CD - immunology Biomedical and Life Sciences Biomedicine CD11b Antigen - biosynthesis CD11b Antigen - immunology Cytokines Down-Regulation - immunology E coli Endothelial Protein C Receptor Endothelium Humans Immunology Inflammation Internal Medicine Leukocytes Protein C - immunology Protein C - metabolism Proteins Receptor, PAR-1 - biosynthesis Receptor, PAR-1 - immunology Receptors, Cell Surface - biosynthesis Receptors, Cell Surface - immunology Review Sepsis Signal Transduction - immunology Thrombosis Thrombosis - blood Thrombosis - immunology Thrombosis - therapy United States > US Oklahoma Histones Thrombin Sepsis Inflammation Thrombomodulin Reperfusion injury
ISSN:	1863-2297, 1863-2300, 1863-2300
Online Access:	Get full text
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