Prophylactic Cranial Irradiation in Extensive Small-Cell Lung Cancer

Symptomatic brain metastases are a major clinical problem in small-cell lung cancer. This trial compared prophylactic cranial irradiation with observation in patients with small-cell lung cancer who had had any response to chemotherapy. Prophylactic irradiation reduced the risk of symptomatic brain...

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Bibliographic Details
Published in:	The New England journal of medicine Vol. 357; no. 7; pp. 664 - 672
Main Authors:	Slotman, Ben, Faivre-Finn, Corinne, Kramer, Gijs, Rankin, Elaine, Snee, Michael, Hatton, Matthew, Postmus, Pieter, Collette, Laurence, Musat, Elena, Senan, Suresh
Format:	Journal Article
Language:	English
Published:	Boston, MA Massachusetts Medical Society 16.08.2007
Subjects:	Adult Aged Biological and medical sciences Brain Brain Neoplasms - epidemiology Brain Neoplasms - prevention & control Brain Neoplasms - secondary Carcinoma, Small Cell - drug therapy Carcinoma, Small Cell - mortality Carcinoma, Small Cell - radiotherapy Carcinoma, Small Cell - secondary Clinical trials Combined Modality Therapy Cranial Irradiation Disease-Free Survival Female General aspects Humans Lung cancer Lung Neoplasms - drug therapy Lung Neoplasms - mortality Lung Neoplasms - pathology Lung Neoplasms - radiotherapy Male Medical imaging Medical sciences Middle Aged Prevention and actions Preventive medicine Public health. Hygiene Public health. Hygiene-occupational medicine Quality of Life Radiation therapy Risk Risk factors Survival Analysis Medicine Prevention Lung disease Treatment Respiratory disease Lung cancer Bonchopulmonary small cell carcinoma Irradiation Bronchus disease Skull Malignant tumor Radiotherapy
ISSN:	0028-4793, 1533-4406, 1533-4406
Online Access:	Get full text
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