Plasma protein binding prediction focusing on residue-level features and circularity of cyclic peptides by deep learning

Abstract Motivation In recent years, cyclic peptide drugs have been receiving increasing attention because they can target proteins that are difficult to be tackled by conventional small-molecule drugs or antibody drugs. Plasma protein binding rate (%PPB) is a significant pharmacokinetic property of...

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Bibliographic Details

Published in:	Bioinformatics Vol. 38; no. 4; pp. 1110 - 1117
Main Authors:	Li, Jianan, Yanagisawa, Keisuke, Yoshikawa, Yasushi, Ohue, Masahito, Akiyama, Yutaka
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 27.01.2022
Subjects:	Blood Proteins Deep Learning Original Papers Peptides, Cyclic Protein Binding Software
ISSN:	1367-4803, 1367-4811, 1460-2059, 1367-4811
Online Access:	Get full text
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