Systematic literature review and validity evaluation of the Expanded Disability Status Scale (EDSS) and the Multiple Sclerosis Functional Composite (MSFC) in patients with multiple sclerosis

Background There are a number of instruments that describe severity and progression of multiple sclerosis and they are increasingly used as endpoints to assess the effectiveness of therapeutic interventions. We examined to what extent the psychometric properties of two accepted instruments – EDSS an...

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Veröffentlicht in:	BMC neurology Jg. 14; H. 1; S. 58
Hauptverfasser:	Meyer-Moock, Sandra, Feng, You-Shan, Maeurer, Mathias, Dippel, Franz-Werner, Kohlmann, Thomas
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 25.03.2014 Springer Nature B.V
Schlagworte:	Clinical Trials as Topic - methods Demyelinating diseases Disability Evaluation Humans Medicine Medicine & Public Health Multiple Sclerosis - diagnosis Multiple Sclerosis - epidemiology Multiple Sclerosis - physiopathology Neurochemistry Neurology Neurosurgery Psychometrics - methods Psychometrics - standards Research Article Expanded Disability Status Scale (EDSS) Validity Multiple sclerosis Multiple Sclerosis Functional Composite (MSFC) Sensitivity of change Reliability Psychometric properties
ISSN:	1471-2377, 1471-2377
Online-Zugang:	Volltext
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