Impaired natural killer cell‐induced antibody‐dependent cell‐mediated cytotoxicity is associated with human immunodeficiency virus‐1 disease progression

Summary This study evaluates the correlation between natural killer (NK) cell function and human immunodeficiency virus (HIV)‐1 disease progression in 133 untreated HIV‐1 positive Chinese subjects, including 41 former plasma donors (FPDs) and 92 men who have sex with men, and 35 HIV‐negative control...

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Bibliographic Details
Published in:	Clinical and experimental immunology Vol. 171; no. 1; pp. 107 - 116
Main Authors:	Jia, M., Li, D., He, X., Zhao, Y., Peng, H., Ma, P., Hong, K., Liang, H., Shao, Y.
Format:	Journal Article
Language:	English
Published:	Oxford Blackwell 01.01.2013 Oxford University Press Blackwell Science Inc
Subjects:	Adult Analytical, structural and metabolic biochemistry Antibody-Dependent Cell Cytotoxicity - genetics Antibody-Dependent Cell Cytotoxicity - immunology Antibody-dependent cell-mediated cytotoxicity Asian Continental Ancestry Group - genetics Biological and medical sciences CD16 antigen CD4 antigen CD4 Lymphocyte Count CD56 Antigen - analysis CD56 Antigen - immunology Disease Progression Female Flow cytometry Fundamental and applied biological sciences. Psychology Genotyping GPI-Linked Proteins - analysis GPI-Linked Proteins - immunology Haplotypes Histocompatibility antigen HLA HIV Infections - genetics HIV Infections - immunology HIV-1 - immunology HLA Antigens - genetics HLA Antigens - immunology Human immunodeficiency virus 1 human immunodeficiency virus type 1 human leucocyte antigen class I Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunodeficiency Immunopathology Infection Infectious diseases Killer Cells, Natural - immunology Leukocytes Male Medical sciences Middle Aged Natural killer cells NK Cell Lectin-Like Receptor Subfamily C - analysis NK Cell Lectin-Like Receptor Subfamily C - immunology NKG2 antigen Original receptors Receptors, IgG - analysis Receptors, IgG - immunology Receptors, KIR2DL1 - analysis Receptors, KIR2DL1 - immunology Sex Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Load - immunology Immunopathology HLA-System Immune response HIV-1 virus receptors antibody-dependent cell-mediated cytotoxicity Retroviridae AIDS Biochemistry Immune deficiency Lentivirus Infection Virus Natural killer cell Associated virus human immunodeficiency virus type 1 natural killer cells Association Viral disease Antibody-dependent cell cytotoxicity Human immunodeficiency virus human leucocyte antigen class I Biological receptor
ISSN:	0009-9104, 1365-2249, 1365-2249
Online Access:	Get full text
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