A fully coupled computational fluid dynamics – agent-based model of atherosclerotic plaque development: Multiscale modeling framework and parameter sensitivity analysis

Peripheral Artery Disease (PAD) is an atherosclerotic disorder that leads to impaired lumen patency through intimal hyperplasia and the build-up of plaques, mainly localized in areas of disturbed flow. Computational models can provide valuable insights in the pathogenesis of atherosclerosis and act...

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Bibliographic Details
Published in:	Computers in biology and medicine Vol. 118; p. 103623
Main Authors:	Corti, Anna, Chiastra, Claudio, Colombo, Monika, Garbey, Marc, Migliavacca, Francesco, Casarin, Stefano
Format:	Journal Article
Language:	English
Published:	United States Elsevier Ltd 01.03.2020 Elsevier Limited
Subjects:	Agent-based model Agent-based models Arteriosclerosis Atherosclerosis Blood vessels Cell size Computational fluid dynamics Computer applications Computer modeling Computer simulation Coupling ECM Extracellular matrix Fluid dynamics Geometry Hemodynamics Hyperplasia Internal Medicine Lipid plaque Lipids Mathematical models Multiscale analysis Multiscale model Other Parameter identification Parameter sensitivity Pathogenesis Pathology Physiology Plaques Prediction models Remodeling Sensitivity analysis Simulation SMC Three dimensional models Two dimensional models Vascular diseases Veins & arteries Wall shear stress United States > US Multiscale model Lipid plaque Atherosclerosis SMC Wall shear stress Hemodynamics Remodeling Computer modeling ECM Agent-based model
ISSN:	0010-4825, 1879-0534, 1879-0534
Online Access:	Get full text
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