Protective Effects of Carbon Dots Derived from Phellodendri Chinensis Cortex Carbonisata against Deinagkistrodon acutus Venom-Induced Acute Kidney Injury
Background As an emerging nanomaterial, carbon dots (CDs) have been the focus of tremendous attention for biomedical applications. However, little information is available on their bioactivity of inhibiting acute kidney injury (AKI) induced by snake venom. Methods This study reports the development...
Gespeichert in:
| Veröffentlicht in: | Nanoscale research letters Jg. 14; H. 1; S. 377 - 13 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
New York
Springer US
16.12.2019
Springer Nature B.V SpringerOpen |
| Schlagworte: | |
| ISSN: | 1931-7573, 1556-276X |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Abstract | Background
As an emerging nanomaterial, carbon dots (CDs) have been the focus of tremendous attention for biomedical applications. However, little information is available on their bioactivity of inhibiting acute kidney injury (AKI) induced by snake venom.
Methods
This study reports the development of a green, one-step pyrolysis process to synthesize CDs using Phellodendri Chinensis Cortex (PCC) as the sole precursor, and their potential application as a protectant against
Deinagkistrodon acutus (D. acutus)
venom-induced AKI was investigated for the first time. The AKI model was established by injecting
D. acutus
venom into the abdominal cavity of mice and the potential protective effects of PCC Carbonisata-CDs (PCCC-CDs) on renal abnormalities including dysfunction, inflammatory reactions, tissue damage, and thrombocytopenia at six time points (1, 3, and 12 h, and 1, 2, and 5 days) were investigated.
Results
These results demonstrated that PCCC-CDs significantly inhibited the kidney dysfunction (reduced serum creatinine (SCR), blood urea nitrogen (BUN), urinary total protein (UTP), and microalbuminuria (MALB) concentrations) and the production of chemoattractant (monocyte chemotactic protein 1 (MCP-1)), proinflammatory cytokines (interleukin (IL)-1β), and anti-inflammatory cytokine (IL-10) in response to intraperitoneal injection of
D. acutus
venom. The beneficial effect of PCCC-CDs on the envenomed mice was similar to that on the change in renal histology and thrombocytopenia.
Conclusions
These results demonstrated the remarkable protective effects of PCCC-CDs against AKI induced by
D. acutus
venom, which would not only broaden the biomedical applications of CDs but also provide a potential target for the development of new therapeutic drugs for AKI induced by
D. acutus
snakebite envenomation. |
|---|---|
| AbstractList | Background
As an emerging nanomaterial, carbon dots (CDs) have been the focus of tremendous attention for biomedical applications. However, little information is available on their bioactivity of inhibiting acute kidney injury (AKI) induced by snake venom.
Methods
This study reports the development of a green, one-step pyrolysis process to synthesize CDs using Phellodendri Chinensis Cortex (PCC) as the sole precursor, and their potential application as a protectant against
Deinagkistrodon acutus (D. acutus)
venom-induced AKI was investigated for the first time. The AKI model was established by injecting
D. acutus
venom into the abdominal cavity of mice and the potential protective effects of PCC Carbonisata-CDs (PCCC-CDs) on renal abnormalities including dysfunction, inflammatory reactions, tissue damage, and thrombocytopenia at six time points (1, 3, and 12 h, and 1, 2, and 5 days) were investigated.
Results
These results demonstrated that PCCC-CDs significantly inhibited the kidney dysfunction (reduced serum creatinine (SCR), blood urea nitrogen (BUN), urinary total protein (UTP), and microalbuminuria (MALB) concentrations) and the production of chemoattractant (monocyte chemotactic protein 1 (MCP-1)), proinflammatory cytokines (interleukin (IL)-1β), and anti-inflammatory cytokine (IL-10) in response to intraperitoneal injection of
D. acutus
venom. The beneficial effect of PCCC-CDs on the envenomed mice was similar to that on the change in renal histology and thrombocytopenia.
Conclusions
These results demonstrated the remarkable protective effects of PCCC-CDs against AKI induced by
D. acutus
venom, which would not only broaden the biomedical applications of CDs but also provide a potential target for the development of new therapeutic drugs for AKI induced by
D. acutus
snakebite envenomation. BackgroundAs an emerging nanomaterial, carbon dots (CDs) have been the focus of tremendous attention for biomedical applications. However, little information is available on their bioactivity of inhibiting acute kidney injury (AKI) induced by snake venom.MethodsThis study reports the development of a green, one-step pyrolysis process to synthesize CDs using Phellodendri Chinensis Cortex (PCC) as the sole precursor, and their potential application as a protectant against Deinagkistrodon acutus (D. acutus) venom-induced AKI was investigated for the first time. The AKI model was established by injecting D. acutus venom into the abdominal cavity of mice and the potential protective effects of PCC Carbonisata-CDs (PCCC-CDs) on renal abnormalities including dysfunction, inflammatory reactions, tissue damage, and thrombocytopenia at six time points (1, 3, and 12 h, and 1, 2, and 5 days) were investigated.ResultsThese results demonstrated that PCCC-CDs significantly inhibited the kidney dysfunction (reduced serum creatinine (SCR), blood urea nitrogen (BUN), urinary total protein (UTP), and microalbuminuria (MALB) concentrations) and the production of chemoattractant (monocyte chemotactic protein 1 (MCP-1)), proinflammatory cytokines (interleukin (IL)-1β), and anti-inflammatory cytokine (IL-10) in response to intraperitoneal injection of D. acutus venom. The beneficial effect of PCCC-CDs on the envenomed mice was similar to that on the change in renal histology and thrombocytopenia.ConclusionsThese results demonstrated the remarkable protective effects of PCCC-CDs against AKI induced by D. acutus venom, which would not only broaden the biomedical applications of CDs but also provide a potential target for the development of new therapeutic drugs for AKI induced by D. acutus snakebite envenomation. As an emerging nanomaterial, carbon dots (CDs) have been the focus of tremendous attention for biomedical applications. However, little information is available on their bioactivity of inhibiting acute kidney injury (AKI) induced by snake venom.BACKGROUNDAs an emerging nanomaterial, carbon dots (CDs) have been the focus of tremendous attention for biomedical applications. However, little information is available on their bioactivity of inhibiting acute kidney injury (AKI) induced by snake venom.This study reports the development of a green, one-step pyrolysis process to synthesize CDs using Phellodendri Chinensis Cortex (PCC) as the sole precursor, and their potential application as a protectant against Deinagkistrodon acutus (D. acutus) venom-induced AKI was investigated for the first time. The AKI model was established by injecting D. acutus venom into the abdominal cavity of mice and the potential protective effects of PCC Carbonisata-CDs (PCCC-CDs) on renal abnormalities including dysfunction, inflammatory reactions, tissue damage, and thrombocytopenia at six time points (1, 3, and 12 h, and 1, 2, and 5 days) were investigated.METHODSThis study reports the development of a green, one-step pyrolysis process to synthesize CDs using Phellodendri Chinensis Cortex (PCC) as the sole precursor, and their potential application as a protectant against Deinagkistrodon acutus (D. acutus) venom-induced AKI was investigated for the first time. The AKI model was established by injecting D. acutus venom into the abdominal cavity of mice and the potential protective effects of PCC Carbonisata-CDs (PCCC-CDs) on renal abnormalities including dysfunction, inflammatory reactions, tissue damage, and thrombocytopenia at six time points (1, 3, and 12 h, and 1, 2, and 5 days) were investigated.These results demonstrated that PCCC-CDs significantly inhibited the kidney dysfunction (reduced serum creatinine (SCR), blood urea nitrogen (BUN), urinary total protein (UTP), and microalbuminuria (MALB) concentrations) and the production of chemoattractant (monocyte chemotactic protein 1 (MCP-1)), proinflammatory cytokines (interleukin (IL)-1β), and anti-inflammatory cytokine (IL-10) in response to intraperitoneal injection of D. acutus venom. The beneficial effect of PCCC-CDs on the envenomed mice was similar to that on the change in renal histology and thrombocytopenia.RESULTSThese results demonstrated that PCCC-CDs significantly inhibited the kidney dysfunction (reduced serum creatinine (SCR), blood urea nitrogen (BUN), urinary total protein (UTP), and microalbuminuria (MALB) concentrations) and the production of chemoattractant (monocyte chemotactic protein 1 (MCP-1)), proinflammatory cytokines (interleukin (IL)-1β), and anti-inflammatory cytokine (IL-10) in response to intraperitoneal injection of D. acutus venom. The beneficial effect of PCCC-CDs on the envenomed mice was similar to that on the change in renal histology and thrombocytopenia.These results demonstrated the remarkable protective effects of PCCC-CDs against AKI induced by D. acutus venom, which would not only broaden the biomedical applications of CDs but also provide a potential target for the development of new therapeutic drugs for AKI induced by D. acutus snakebite envenomation.CONCLUSIONSThese results demonstrated the remarkable protective effects of PCCC-CDs against AKI induced by D. acutus venom, which would not only broaden the biomedical applications of CDs but also provide a potential target for the development of new therapeutic drugs for AKI induced by D. acutus snakebite envenomation. Abstract Background As an emerging nanomaterial, carbon dots (CDs) have been the focus of tremendous attention for biomedical applications. However, little information is available on their bioactivity of inhibiting acute kidney injury (AKI) induced by snake venom. Methods This study reports the development of a green, one-step pyrolysis process to synthesize CDs using Phellodendri Chinensis Cortex (PCC) as the sole precursor, and their potential application as a protectant against Deinagkistrodon acutus (D. acutus) venom-induced AKI was investigated for the first time. The AKI model was established by injecting D. acutus venom into the abdominal cavity of mice and the potential protective effects of PCC Carbonisata-CDs (PCCC-CDs) on renal abnormalities including dysfunction, inflammatory reactions, tissue damage, and thrombocytopenia at six time points (1, 3, and 12 h, and 1, 2, and 5 days) were investigated. Results These results demonstrated that PCCC-CDs significantly inhibited the kidney dysfunction (reduced serum creatinine (SCR), blood urea nitrogen (BUN), urinary total protein (UTP), and microalbuminuria (MALB) concentrations) and the production of chemoattractant (monocyte chemotactic protein 1 (MCP-1)), proinflammatory cytokines (interleukin (IL)-1β), and anti-inflammatory cytokine (IL-10) in response to intraperitoneal injection of D. acutus venom. The beneficial effect of PCCC-CDs on the envenomed mice was similar to that on the change in renal histology and thrombocytopenia. Conclusions These results demonstrated the remarkable protective effects of PCCC-CDs against AKI induced by D. acutus venom, which would not only broaden the biomedical applications of CDs but also provide a potential target for the development of new therapeutic drugs for AKI induced by D. acutus snakebite envenomation. As an emerging nanomaterial, carbon dots (CDs) have been the focus of tremendous attention for biomedical applications. However, little information is available on their bioactivity of inhibiting acute kidney injury (AKI) induced by snake venom. This study reports the development of a green, one-step pyrolysis process to synthesize CDs using Phellodendri Chinensis Cortex (PCC) as the sole precursor, and their potential application as a protectant against Deinagkistrodon acutus (D. acutus) venom-induced AKI was investigated for the first time. The AKI model was established by injecting D. acutus venom into the abdominal cavity of mice and the potential protective effects of PCC Carbonisata-CDs (PCCC-CDs) on renal abnormalities including dysfunction, inflammatory reactions, tissue damage, and thrombocytopenia at six time points (1, 3, and 12 h, and 1, 2, and 5 days) were investigated. These results demonstrated that PCCC-CDs significantly inhibited the kidney dysfunction (reduced serum creatinine (SCR), blood urea nitrogen (BUN), urinary total protein (UTP), and microalbuminuria (MALB) concentrations) and the production of chemoattractant (monocyte chemotactic protein 1 (MCP-1)), proinflammatory cytokines (interleukin (IL)-1β), and anti-inflammatory cytokine (IL-10) in response to intraperitoneal injection of D. acutus venom. The beneficial effect of PCCC-CDs on the envenomed mice was similar to that on the change in renal histology and thrombocytopenia. These results demonstrated the remarkable protective effects of PCCC-CDs against AKI induced by D. acutus venom, which would not only broaden the biomedical applications of CDs but also provide a potential target for the development of new therapeutic drugs for AKI induced by D. acutus snakebite envenomation. |
| ArticleNumber | 377 |
| Author | Kong, Hui Zhang, Yue Cheng, Jinjun Sun, Ziwei Zhang, Meiling Wang, Xiaoke Wang, Suna Zhao, Yan Qu, Huihua |
| Author_xml | – sequence: 1 givenname: Meiling surname: Zhang fullname: Zhang, Meiling organization: School of Traditional Chinese Medicine, Beijing University of Chinese Medicine – sequence: 2 givenname: Jinjun surname: Cheng fullname: Cheng, Jinjun organization: School of Traditional Chinese Medicine, Beijing University of Chinese Medicine – sequence: 3 givenname: Ziwei surname: Sun fullname: Sun, Ziwei organization: School of Traditional Chinese Medicine, Beijing University of Chinese Medicine – sequence: 4 givenname: Hui surname: Kong fullname: Kong, Hui organization: School of Traditional Chinese Medicine, Beijing University of Chinese Medicine – sequence: 5 givenname: Yue surname: Zhang fullname: Zhang, Yue organization: School of Life Sciences, Beijing University of Chinese Medicine – sequence: 6 givenname: Suna surname: Wang fullname: Wang, Suna organization: School of Traditional Chinese Medicine, Beijing University of Chinese Medicine – sequence: 7 givenname: Xiaoke surname: Wang fullname: Wang, Xiaoke organization: School of Traditional Chinese Medicine, Beijing University of Chinese Medicine – sequence: 8 givenname: Yan orcidid: 0000-0002-4336-0028 surname: Zhao fullname: Zhao, Yan email: zhaoyandr@gmail.com organization: School of Traditional Chinese Medicine, Beijing University of Chinese Medicine – sequence: 9 givenname: Huihua surname: Qu fullname: Qu, Huihua organization: Center of Scientific Experiment, Beijing University of Chinese Medicine |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31845094$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9ks1uEzEUhUeoiP7AA7BBltiwGZg7M7bHG6QqLRBRiS4AsbMc-zpxSOxieyryKLwtTpMCrUQlS_4759P19TmuDnzwWFXPoXkNMLA3CYBxqBsQdQdiqOFRdQSUsrrl7NtBWYsOak55d1gdp7Rsmp43nD2pDjsYetqI_qj6dRlDRp3dNZJza8sqkWDJRMVZ8OQslO0ZxnJriI1hTS4XuFoFg95ERyYL59Enl8gkxIw_9zaXVFZEzZXzKRe782r-3aUcgylMpcc8JvIVfVjXU29GXdin5RDJR2c8bsjUL8e4eVo9tmqV8Nl-Pqm-vDv_PPlQX3x6P52cXtSasj7XnebGtp2ljcaGzYZBMWA9FVwPbdNR2_aMc60Q0PbWGK4bQFRdN-Nm1toeupNquuOaoJbyKrq1ihsZlJM3ByHOpYrZ6RVK1tmBaW1gUKLXFAYrsAwhSmdbJrCw3u5YV-NsjUajz1Gt7kDv3ni3kPNwLZkAWn6rAF7tATH8GDFluXZJl5Yrj2FMsu1aLnpoBC3Sl_ekyzBGX1olSxhKLlqg_UOqLasF4DesF__W_afg25wUAd8JdAwpRbRSu6yyC9tnuJWERm4TKXeJlCWR2yIGuW0v3HPewh_ytDtPKlo_x_i36P-bfgP2W_TL |
| CitedBy_id | crossref_primary_10_1039_D2NR03321F crossref_primary_10_2147_IJN_S338886 crossref_primary_10_3389_fphar_2023_1118550 crossref_primary_10_3389_fmolb_2023_1223621 crossref_primary_10_1186_s12951_021_01072_3 crossref_primary_10_3389_fphar_2022_815479 crossref_primary_10_1016_j_biopha_2024_116967 crossref_primary_10_3390_molecules26061512 crossref_primary_10_1016_j_biopha_2022_113900 crossref_primary_10_1016_j_scib_2024_08_011 crossref_primary_10_1016_j_ijbiomac_2024_135041 crossref_primary_10_2147_IJN_S431061 crossref_primary_10_3390_molecules28062720 crossref_primary_10_3390_toxins17060280 crossref_primary_10_2147_IJN_S497892 crossref_primary_10_1016_j_colsurfb_2023_113447 crossref_primary_10_1016_j_nxnano_2023_100034 crossref_primary_10_1039_D1NR03740D crossref_primary_10_1186_s12951_023_01795_5 crossref_primary_10_2217_nnm_2019_0369 crossref_primary_10_1002_slct_202500180 crossref_primary_10_1080_10799893_2021_1967392 crossref_primary_10_1039_D3NH00120B crossref_primary_10_1155_2023_3076119 crossref_primary_10_2147_IJN_S291670 crossref_primary_10_1007_s12274_020_3067_3 crossref_primary_10_3390_molecules28041830 crossref_primary_10_1186_s12951_021_00847_y |
| Cites_doi | 10.1084/jem.185.7.1371 10.1186/s12951-017-0296-z 10.1039/C4RA09546D 10.1002/anie.200906154 10.1016/0952-7915(94)90006-X 10.1186/s40409-017-0112-0 10.1016/j.jep.2018.07.002 10.1016/0041-0101(92)90046-8 10.1159/000324228 10.1016/j.ympev.2007.05.019 10.1186/s40409-017-0111-1 10.1038/s41581-018-0015-5 10.1038/ki.1989.70 10.1021/acsnano.7b01023 10.2217/nnm-2018-0285 10.1016/j.toxicon.2010.01.027 10.1111/nep.12327 10.4269/ajtmh.2000.63.313 10.3390/toxins7051532 10.1155/2014/781857 10.6061/clinics/2013(06)13 10.1016/j.carbon.2013.03.009 10.1186/1556-276X-8-276 10.1039/c1cc11943e 10.1590/S0036-46652013000500001 10.1039/C4NR02657H 10.1055/s-2004-835678 10.4103/1947-2714.120795 10.1007/s00795-011-0559-y 10.1016/j.fct.2018.05.016 10.1111/jpi.12123 10.1016/j.thromres.2011.10.010 10.1039/C4NR04267K 10.1039/C5RA27662D 10.1016/j.biomaterials.2016.08.047 10.2217/nnm-2017-0297 10.1016/j.toxicon.2014.04.001 10.1016/j.snb.2015.02.104 10.1007/s00204-014-1264-0 10.1128/AEM.02608-15 |
| ContentType | Journal Article |
| Copyright | The Author(s). 2019 Nanoscale Research Letters is a copyright of Springer, (2019). All Rights Reserved. © 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Copyright Springer Nature B.V. Dec 2019 |
| Copyright_xml | – notice: The Author(s). 2019 – notice: Nanoscale Research Letters is a copyright of Springer, (2019). All Rights Reserved. © 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: Copyright Springer Nature B.V. Dec 2019 |
| DBID | C6C AAYXX CITATION NPM 7QF 7QO 7QQ 7SC 7SE 7SP 7SR 7TA 7TB 7U5 8BQ 8FD 8FE 8FG 8FH ABJCF ABUWG AEUYN AFKRA AZQEC BBNVY BENPR BGLVJ BHPHI CCPQU D1I DWQXO F28 FR3 GNUQQ H8D H8G HCIFZ JG9 JQ2 KB. KR7 L7M LK8 L~C L~D M7P P64 PDBOC PHGZM PHGZT PIMPY PKEHL PQEST PQGLB PQQKQ PQUKI PRINS 7X8 5PM DOA |
| DOI | 10.1186/s11671-019-3198-1 |
| DatabaseName | Springer Nature OA Free Journals CrossRef PubMed Aluminium Industry Abstracts Biotechnology Research Abstracts Ceramic Abstracts Computer and Information Systems Abstracts Corrosion Abstracts Electronics & Communications Abstracts Engineered Materials Abstracts Materials Business File Mechanical & Transportation Engineering Abstracts Solid State and Superconductivity Abstracts METADEX Technology Research Database ProQuest SciTech Collection ProQuest Technology Collection ProQuest Natural Science Collection ProQuest Materials Science & Engineering ProQuest Central (Alumni) ProQuest One Sustainability ProQuest Central UK/Ireland ProQuest Central Essentials Biological Science Collection ProQuest Central Technology Collection Natural Science Collection ProQuest One ProQuest Materials Science Collection ProQuest Central ANTE: Abstracts in New Technology & Engineering Engineering Research Database ProQuest Central Student Aerospace Database Copper Technical Reference Library SciTech Premium Collection Materials Research Database ProQuest Computer Science Collection Materials Science Database Civil Engineering Abstracts Advanced Technologies Database with Aerospace ProQuest Biological Science Collection Computer and Information Systems Abstracts Academic Computer and Information Systems Abstracts Professional Biological Science Database Biotechnology and BioEngineering Abstracts Materials Science Collection ProQuest Central Premium ProQuest One Academic Publicly Available Content Database ProQuest One Academic Middle East (New) ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic (retired) ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic PubMed Central (Full Participant titles) Directory of Open Access Journals |
| DatabaseTitle | CrossRef PubMed Publicly Available Content Database Materials Research Database ProQuest Central Student ProQuest Central Essentials ProQuest Computer Science Collection Computer and Information Systems Abstracts SciTech Premium Collection ProQuest Central China Materials Business File ProQuest One Applied & Life Sciences ProQuest One Sustainability Engineered Materials Abstracts Natural Science Collection Biological Science Collection ProQuest Central (New) ANTE: Abstracts in New Technology & Engineering Aluminium Industry Abstracts ProQuest Biological Science Collection ProQuest One Academic Eastern Edition Electronics & Communications Abstracts ProQuest Technology Collection Ceramic Abstracts Biological Science Database Biotechnology and BioEngineering Abstracts ProQuest One Academic UKI Edition Solid State and Superconductivity Abstracts Engineering Research Database ProQuest One Academic ProQuest One Academic (New) Technology Collection Technology Research Database Computer and Information Systems Abstracts – Academic ProQuest One Academic Middle East (New) Mechanical & Transportation Engineering Abstracts Materials Science Collection ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest Natural Science Collection ProQuest Central Aerospace Database Copper Technical Reference Library Biotechnology Research Abstracts ProQuest Central Korea Materials Science Database Advanced Technologies Database with Aerospace ProQuest Materials Science Collection Civil Engineering Abstracts ProQuest SciTech Collection METADEX Computer and Information Systems Abstracts Professional Materials Science & Engineering Collection Corrosion Abstracts MEDLINE - Academic |
| DatabaseTitleList | Publicly Available Content Database MEDLINE - Academic PubMed Publicly Available Content Database |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: PIMPY name: Publicly Available Content Database url: http://search.proquest.com/publiccontent sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Engineering |
| EISSN | 1556-276X |
| EndPage | 13 |
| ExternalDocumentID | oai_doaj_org_article_63f86ccd18a94c518f9ef9e99004269e PMC6915193 31845094 10_1186_s11671_019_3198_1 |
| Genre | Journal Article |
| GrantInformation_xml | – fundername: Young Teacher Special Projects of Beijing University of Chinese Medicine grantid: 81503344 – fundername: National Natural Science Foundation of China grantid: 81573573; 81473338 funderid: http://dx.doi.org/10.13039/501100001809 – fundername: National Natural Science Foundation of China grantid: 81573573 – fundername: National Natural Science Foundation of China grantid: 81473338 – fundername: ; grantid: 81503344 – fundername: ; grantid: 81573573; 81473338 |
| GroupedDBID | -A0 .4S .86 .DC 0R~ 123 29M 2VQ 2WC 4.4 40G 5VS 6NX 8FE 8FG 8FH AAFWJ ABJCF ABMNI ACGFO ACGFS ACIWK ACPRK ADBBV ADINQ ADRAZ AEGXH AENEX AEUYN AFGCZ AFKRA AFPKN AFRAH AHBYD AHSBF AHYZX ALMA_UNASSIGNED_HOLDINGS AMKLP AMTXH AOIJS ARCSS BAPOH BBNVY BCNDV BENPR BGLVJ BGNMA BHPHI C1A C24 C6C CAG CCPQU COF CS3 D1I DU5 EBS EDO EJD F5P GROUPED_DOAJ GX1 H13 HCIFZ HH5 HYE HZ~ I09 IAO IPNFZ IZQ KB. KDC KQ8 LK8 M48 M4Y M7P MM. M~E NU0 O5R O5S O9- OK1 P2P PDBOC PGMZT PIMPY PROAC RIG RNS RPM RPX RSV SCM SDH SOJ TR2 TSK TUS U2A ~KM AAYXX AFFHD CITATION OVT PHGZM PHGZT PQGLB NPM 7QF 7QO 7QQ 7SC 7SE 7SP 7SR 7TA 7TB 7U5 8BQ 8FD ABUWG AZQEC DWQXO F28 FR3 GNUQQ H8D H8G JG9 JQ2 KR7 L7M L~C L~D P64 PKEHL PQEST PQQKQ PQUKI PRINS 7X8 5PM |
| ID | FETCH-LOGICAL-c564t-3c7df23f50ce06b88a6164597c82035f24677cae1ef4fdd7c01eea33b7db2f413 |
| IEDL.DBID | DOA |
| ISICitedReferencesCount | 32 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000509988800002&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1931-7573 |
| IngestDate | Fri Oct 03 12:40:34 EDT 2025 Tue Nov 04 01:53:06 EST 2025 Sun Nov 09 09:39:34 EST 2025 Wed Oct 08 14:21:20 EDT 2025 Wed Oct 08 14:21:06 EDT 2025 Wed Feb 19 02:31:49 EST 2025 Tue Nov 18 22:20:04 EST 2025 Sat Nov 29 02:31:08 EST 2025 Fri Feb 21 02:34:36 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | Protective effect venom Phellodendri Chinensis Cortex Carbonisata-carbon dots Acute kidney injury Deinagkistrodon acutus venom |
| Language | English |
| License | Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c564t-3c7df23f50ce06b88a6164597c82035f24677cae1ef4fdd7c01eea33b7db2f413 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| ORCID | 0000-0002-4336-0028 |
| OpenAccessLink | https://doaj.org/article/63f86ccd18a94c518f9ef9e99004269e |
| PMID | 31845094 |
| PQID | 2327211795 |
| PQPubID | 2034687 |
| PageCount | 13 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_63f86ccd18a94c518f9ef9e99004269e pubmedcentral_primary_oai_pubmedcentral_nih_gov_6915193 proquest_miscellaneous_2327941095 proquest_journals_3196712154 proquest_journals_2327211795 pubmed_primary_31845094 crossref_citationtrail_10_1186_s11671_019_3198_1 crossref_primary_10_1186_s11671_019_3198_1 springer_journals_10_1186_s11671_019_3198_1 |
| PublicationCentury | 2000 |
| PublicationDate | 2019-12-16 |
| PublicationDateYYYYMMDD | 2019-12-16 |
| PublicationDate_xml | – month: 12 year: 2019 text: 2019-12-16 day: 16 |
| PublicationDecade | 2010 |
| PublicationPlace | New York |
| PublicationPlace_xml | – name: New York – name: United States – name: Heidelberg |
| PublicationTitle | Nanoscale research letters |
| PublicationTitleAbbrev | Nanoscale Res Lett |
| PublicationTitleAlternate | Nanoscale Res Lett |
| PublicationYear | 2019 |
| Publisher | Springer US Springer Nature B.V SpringerOpen |
| Publisher_xml | – name: Springer US – name: Springer Nature B.V – name: SpringerOpen |
| References | Ding, Wei, Xiong (CR12) 2014; 6 de Stoppelaar, van’t Veer, van der Poll (CR42) 2014; 112 Torrez, Said, Quiroga, Duarte, Franca (CR34) 2014; 85 Yan, Zhao, Luo, Xiong, Liu, Cheng, Wang, Zhang, Qu (CR19) 2017; 15 Rucavado, Escalante, Franceschi, Chaves, Leon, Cury, Ovadia, Gutierrez (CR6) 2000; 63 Ruan, Qian, Shen, Zhu, Jiang, He, Gao (CR11) 2014; 6 Xiong, Li, Huang, He, Yu (CR1) 2018; 225 Albuquerque, Jacinto, Silva Junior, Lima, Veras Mdo, Daher (CR32) 2013; 55 Berger, Santi, Beys-da-Silva, Oliveira, Caliari, Yates, Vieira, Guimaraes (CR35) 2015; 89 Valente, Soares, Rocha, Cardoso, Maccariello (CR44) 2013; 68 Shi, Wang, Long, Cheng, Chen, Zheng, Huang (CR20) 2011; 47 Jansen, Florquin, Roelofs (CR26) 2018; 14 Lloyd, Minto, Dorf, Proudfoot, Wells, Salant, Gutierrezramos (CR39) 1997; 185 Pan, Zhu, Lou, Mao, Lin, Tian, Zhang (CR13) 2014; 5 Schall, Bacon (CR38) 1994; 6 Cheng, Mao, Liu, Chiang, Liao, Yang (CR3) 2017; 23 Dharod, Patil, Deshpande, Gulhane, Patil, Bansod (CR33) 2013; 5 Ghoshal, Bhattacharyya (CR40) 2014; 2014 Liu, He, Wang, Zhou, Li, Zhang, Luo, Chen, Tang, Yu (CR7) 2017; 23 Katkar, Sundaram, Hemshekhar, Sharma, Santhosh, Sunitha, Rangappa, Girish, Kemparaju (CR36) 2014; 56 Tang, Dong, Kong (CR2) 2010; 56 Alexandra, Mónica, Teresa, Loría, Raghuvir, José María (CR45) 2005; 93 Huang, He, Peng, Zhao, Zhao (CR29) 2007; 44 Chugh (CR4) 1989; 35 Ziwei Sun, Cheng, Zhang, Zhang, Xiong, Zhao, Qu (CR22) 2018; 46 Mehta, Jha, Basu, Singhal, Kailasa, Chemical (CR14) 2015; 213 Kawazu, Nishino, Obata, Furusu, Miyazaki, Abe, Koji, Kohno (CR30) 2012; 45 Cerletti, Tamburrelli, Izzi, Gianfagna, de Gaetano (CR41) 2012; 129 Boccardo, Remuzzi, Galbusera (CR43) 2004; 30 Li, He, Kang, Huang, Liu, Liu, Lian, Tsang, Yang, Lee (CR17) 2010; 49 Blasgarcia, Baldoví, Polo, Victor, Garcia, Herance (CR28) 2016; 6 Al-Asmari, Khan, Manthiri, Al-Khlaiwi, Al-Asmari, Ibrahim (CR31) 2018; 118 Albuquerque, Silva, Jacinto, Lima, Lima, Amaral, Veras Mdo, Mota, Daher (CR5) 2014; 19 Cheng, Zhang, Sun, Lu, Xiong, Luo, Kong, Wang, Qu, Zhao (CR15) 2019; 14 Carroll, Thalley, Theakston, Laing (CR8) 1992; 30 Lee, Lee, Liang, Leu, Lin, Chiang, Yang (CR9) 2016; 82 Jian, Wu, Lin, Li, Lin, Harroun, Lai, Huang (CR18) 2017; 11 Patino, Quintana, Gutierrez, Rucavado, Benjumea, Pereanez (CR37) 2015; 7 Hu, Song, Xu, Zhong, Peng, Ji, Zhu, Yang, Zhou, Su, Chen, He, He (CR21) 2016; 108 Barsoum, Francis, Sitprija (CR24) 1999 Rodrigues Sgrignolli, Florido Mendes, Carlos, Burdmann (CR25) 2011; 119 Liu, Wang, Yan, Zhang, Zhang, Cheng, Lu, Qu, Wang, Zhao (CR23) 2018; 13 Xiaoyou, Robert, Yunlong, Ploehn, Latha, Kyle, Scrivens (CR10) 2015; 126 Wang, Huang, Long, Wang, Zhang, Rui, Liang, Ping, Zheng (CR16) 2013; 59 Gao, Shen, Zhao, Dong, Jia, Wu, Cui, Zhang, Wang (CR27) 2013; 8 A Blasgarcia (3198_CR28) 2016; 6 TJ Schall (3198_CR38) 1994; 6 Q Wang (3198_CR16) 2013; 59 M Berger (3198_CR35) 2015; 89 L Rodrigues Sgrignolli (3198_CR25) 2011; 119 J Cheng (3198_CR15) 2019; 14 PL Albuquerque (3198_CR5) 2014; 19 C Valente (3198_CR44) 2013; 68 H Pan (3198_CR13) 2014; 5 MV Dharod (3198_CR33) 2013; 5 SF de Stoppelaar (3198_CR42) 2014; 112 P Boccardo (3198_CR43) 2004; 30 MPB Jansen (3198_CR26) 2018; 14 K Ghoshal (3198_CR40) 2014; 2014 CL Cheng (3198_CR3) 2017; 23 C Cerletti (3198_CR41) 2012; 129 RS Barsoum (3198_CR24) 1999 Y Xiong (3198_CR1) 2018; 225 X Xiaoyou (3198_CR10) 2015; 126 GD Katkar (3198_CR36) 2014; 56 AC Patino (3198_CR37) 2015; 7 SB Carroll (3198_CR8) 1992; 30 KS Chugh (3198_CR4) 1989; 35 CH Lee (3198_CR9) 2016; 82 FL Ziwei Sun (3198_CR22) 2018; 46 Z Hu (3198_CR21) 2016; 108 R Alexandra (3198_CR45) 2005; 93 HJ Jian (3198_CR18) 2017; 11 X Yan (3198_CR19) 2017; 15 PP Torrez (3198_CR34) 2014; 85 S Huang (3198_CR29) 2007; 44 J Liu (3198_CR7) 2017; 23 H Ding (3198_CR12) 2014; 6 VN Mehta (3198_CR14) 2015; 213 AK Al-Asmari (3198_CR31) 2018; 118 W Shi (3198_CR20) 2011; 47 Z Gao (3198_CR27) 2013; 8 PL Albuquerque (3198_CR32) 2013; 55 T Kawazu (3198_CR30) 2012; 45 A Rucavado (3198_CR6) 2000; 63 H Li (3198_CR17) 2010; 49 CM Lloyd (3198_CR39) 1997; 185 Y Tang (3198_CR2) 2010; 56 S Ruan (3198_CR11) 2014; 6 X Liu (3198_CR23) 2018; 13 |
| References_xml | – volume: 185 start-page: 1371 issue: 7 year: 1997 end-page: 1380 ident: CR39 article-title: RANTES and monocyte chemoattractant protein–1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis publication-title: J Exp Med doi: 10.1084/jem.185.7.1371 – volume: 15 start-page: 60 issue: 1 year: 2017 ident: CR19 article-title: Hemostatic bioactivity of novel pollen Typhae Carbonisata-derived carbon quantum dots publication-title: J Nanobiotechnol doi: 10.1186/s12951-017-0296-z – volume: 5 start-page: 6543 issue: 9 year: 2014 end-page: 6552 ident: CR13 article-title: Graphene-based photocatalysts for oxygen evolution from water publication-title: RSC Adv doi: 10.1039/C4RA09546D – volume: 49 start-page: 4430 issue: 26 year: 2010 end-page: 4434 ident: CR17 article-title: Water-soluble fluorescent carbon quantum dots and photocatalyst design publication-title: Angew Chem Int Ed Engl doi: 10.1002/anie.200906154 – volume: 6 start-page: 865 issue: 6 year: 1994 end-page: 873 ident: CR38 article-title: Chemokines, leukocyte trafficking, and inflammation publication-title: Curr Opin Immunol doi: 10.1016/0952-7915(94)90006-X – volume: 23 start-page: 22 year: 2017 ident: CR7 article-title: Preparation and neutralization efficacy of IgY antibodies raised against Deinagkistrodon acutus venom publication-title: J Venom Anim Toxins Trop Dis doi: 10.1186/s40409-017-0112-0 – volume: 225 start-page: 189 year: 2018 end-page: 197 ident: CR1 article-title: Anti-Deinagkistrodon acutus venom properties of ethanolic root extract from Cynanchum paniculatum (Bunge) kitag and its GC-MS analysis publication-title: J Ethnopharmacol doi: 10.1016/j.jep.2018.07.002 – volume: 30 start-page: 1017 issue: 9 year: 1992 end-page: 1025 ident: CR8 article-title: Comparison of the purity and efficacy of affinity purified avian antivenoms with commercial equine crotalid antivenoms publication-title: Toxicon doi: 10.1016/0041-0101(92)90046-8 – volume: 119 start-page: c131 issue: 2 year: 2011 end-page: c136 ident: CR25 article-title: Acute kidney injury caused by bothrops snake venom publication-title: Nephron Clin Pract doi: 10.1159/000324228 – year: 1999 ident: CR24 publication-title: Renal involvement in tropical diseases – volume: 44 start-page: 942 issue: 3 year: 2007 end-page: 952 ident: CR29 article-title: Molecular phylogeography of endangered sharp-snouted pitviper (Deinagkistrodon acutus; Reptilia, Viperidae) in Mainland China publication-title: Mol Phylogenet Evol doi: 10.1016/j.ympev.2007.05.019 – volume: 23 start-page: 20 issue: 1 year: 2017 ident: CR3 article-title: Deinagkistrodon acutus envenomation: a report of three cases publication-title: J Venom Anim Toxins Trop Dis doi: 10.1186/s40409-017-0111-1 – volume: 14 start-page: 457 issue: Suppl. 1 year: 2018 end-page: 471 ident: CR26 article-title: The role of platelets in acute kidney injury publication-title: Nat Rev Nephrol doi: 10.1038/s41581-018-0015-5 – volume: 35 start-page: 891 issue: 3 year: 1989 end-page: 907 ident: CR4 article-title: Snake-bite-induced acute renal failure in India publication-title: Kidney Int doi: 10.1038/ki.1989.70 – volume: 11 start-page: 6703 issue: 7 year: 2017 end-page: 6716 ident: CR18 article-title: Super-cationic carbon quantum dots synthesized from spermidine as an eye drop formulation for topical treatment of bacterial keratitis publication-title: ACS Nano doi: 10.1021/acsnano.7b01023 – volume: 14 start-page: 431 issue: 4 year: 2019 end-page: 446 ident: CR15 article-title: Hemostatic and hepatoprotective bioactivity of Junci Medulla Carbonisata-derived carbon dots publication-title: Nanomedicine (Lond) doi: 10.2217/nnm-2018-0285 – volume: 56 start-page: 45 issue: 1 year: 2010 end-page: 54 ident: CR2 article-title: Effects of heating on the immunogenicity and biological toxicity of Deinagkistrodon acutus venom and its fractions publication-title: Toxicon doi: 10.1016/j.toxicon.2010.01.027 – volume: 46 start-page: S308 year: 2018 end-page: S317 ident: CR22 article-title: Hemostatic bioactivity of novel Schizonepetae Spica Carbonisata-derived carbon dots via platelet counts elevation publication-title: Artif Cells Blood Substitutes Biotechnol – volume: 19 start-page: 764 issue: 12 year: 2014 end-page: 770 ident: CR5 article-title: Acute kidney injury after snakebite accident treated in a Brazilian tertiary care centre publication-title: Nephrology (Carlton) doi: 10.1111/nep.12327 – volume: 63 start-page: 313 issue: 5–6 year: 2000 end-page: 319 ident: CR6 article-title: Inhibition of local hemorrhage and dermonecrosis induced by Bothrops asper snake venom: effectiveness of early in situ administration of the peptidomimetic metalloproteinase inhibitor batimastat and the chelating agent CaNa2EDTA publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.2000.63.313 – volume: 7 start-page: 1532 issue: 5 year: 2015 end-page: 1543 ident: CR37 article-title: Extracts of Renealmia alpinia (Rottb.) MAAS protect against lethality and systemic hemorrhage induced by Bothrops asper venom: insights from a model with extract administration before venom injection publication-title: Toxins doi: 10.3390/toxins7051532 – volume: 2014 start-page: 781857 year: 2014 ident: CR40 article-title: Overview of platelet physiology: its hemostatic and nonhemostatic role in disease pathogenesis publication-title: TheScientificWorldJournal doi: 10.1155/2014/781857 – volume: 68 start-page: 803 issue: 6 year: 2013 end-page: 808 ident: CR44 article-title: The evaluation of sequential platelet counts has prognostic value for acute kidney injury patients requiring dialysis in the intensive care setting publication-title: Clinics (Sao Paulo) doi: 10.6061/clinics/2013(06)13 – volume: 59 start-page: 192 issue: 4 year: 2013 end-page: 199 ident: CR16 article-title: Hollow luminescent carbon dots for drug delivery publication-title: Carbon doi: 10.1016/j.carbon.2013.03.009 – volume: 8 start-page: 276 issue: 1 year: 2013 ident: CR27 article-title: Carbon dots: a safe nanoscale substance for the immunologic system of mice publication-title: Nanoscale Res Lett doi: 10.1186/1556-276X-8-276 – volume: 47 start-page: 6695 issue: 23 year: 2011 end-page: 6697 ident: CR20 article-title: Carbon nanodots as peroxidase mimetics and their applications to glucose detection publication-title: Chem Commun (Camb) doi: 10.1039/c1cc11943e – volume: 112 start-page: 666 issue: 4 year: 2014 end-page: 677 ident: CR42 article-title: The role of platelets in sepsis publication-title: Thromb Haemost – volume: 55 start-page: 295 issue: 5 year: 2013 end-page: 301 ident: CR32 article-title: Acute kidney injury caused by Crotalus and Bothrops snake venom: a review of epidemiology, clinical manifestations and treatment publication-title: Rev Inst Med Trop Sao Paulo doi: 10.1590/S0036-46652013000500001 – volume: 6 start-page: 10040 issue: 17 year: 2014 end-page: 10047 ident: CR11 article-title: A simple one-step method to prepare fluorescent carbon dots and their potential application in non-invasive glioma imaging publication-title: Nanoscale doi: 10.1039/C4NR02657H – volume: 30 start-page: 579 issue: 5 year: 2004 end-page: 589 ident: CR43 article-title: Platelet dysfunction in renal failure publication-title: Semin Thromb Hemost doi: 10.1055/s-2004-835678 – volume: 93 start-page: 123 issue: 01 year: 2005 end-page: 131 ident: CR45 article-title: Haemostasis, thrombocytopenia and platelet hypoaggregation induced by Bothrops asper snake venom publication-title: Toxins Involved Contrib Metalloproteinase-Induced Pulmon Hemorr – volume: 5 start-page: 594 issue: 10 year: 2013 end-page: 599 ident: CR33 article-title: Clinical predictors of acute kidney injury following snake bite envenomation publication-title: N Am J Med Sci doi: 10.4103/1947-2714.120795 – volume: 45 start-page: 190 issue: 4 year: 2012 end-page: 198 ident: CR30 article-title: Production and degradation of extracellular matrix in reversible glomerular lesions in rat model of habu snake venom-induced glomerulonephritis publication-title: Med Mol Morphol doi: 10.1007/s00795-011-0559-y – volume: 118 start-page: 105 year: 2018 end-page: 110 ident: CR31 article-title: Protective effects of a natural herbal compound quercetin against snake venom-induced hepatic and renal toxicities in rats publication-title: Food Chem Toxicol doi: 10.1016/j.fct.2018.05.016 – volume: 56 start-page: 295 issue: 3 year: 2014 end-page: 312 ident: CR36 article-title: Melatonin alleviates Echis carinatus venom-induced toxicities by modulating inflammatory mediators and oxidative stress publication-title: J Pineal Res doi: 10.1111/jpi.12123 – volume: 129 start-page: 263 issue: 3 year: 2012 end-page: 266 ident: CR41 article-title: Platelet-leukocyte interactions in thrombosis publication-title: Thromb Res doi: 10.1016/j.thromres.2011.10.010 – volume: 6 start-page: 13817 issue: 22 year: 2014 end-page: 13823 ident: CR12 article-title: Nitrogen and sulfur co-doped carbon dots with strong blue luminescence publication-title: Nanoscale doi: 10.1039/C4NR04267K – volume: 6 start-page: 30611 issue: 36 year: 2016 end-page: 30622 ident: CR28 article-title: Toxicological properties of two fluorescent carbon quantum dots with onion ring morphology and their usefulness as bioimaging agents publication-title: RSC Adv doi: 10.1039/C5RA27662D – volume: 126 start-page: 12736 issue: 40 year: 2015 end-page: 12737 ident: CR10 article-title: Electrophoretic analysis and purification of fluorescent single-walled carbon nanotube fragments publication-title: J Am Chem Soc – volume: 108 start-page: 187 year: 2016 end-page: 196 ident: CR21 article-title: Aqueous synthesized quantum dots interfere with the NF-kappaB pathway and confer anti-tumor, anti-viral and anti-inflammatory effects publication-title: Biomaterials doi: 10.1016/j.biomaterials.2016.08.047 – volume: 13 start-page: 391 issue: 4 year: 2018 end-page: 405 ident: CR23 article-title: Novel Phellodendri cortex (Huang Bo)-derived carbon dots and their hemostatic effect publication-title: Nanomedicine (Lond) doi: 10.2217/nnm-2017-0297 – volume: 85 start-page: 27 year: 2014 end-page: 30 ident: CR34 article-title: Forest pit viper (Bothriopsis bilineata bilineata) bite in the Brazilian Amazon with acute kidney injury and persistent thrombocytopenia publication-title: Toxicon doi: 10.1016/j.toxicon.2014.04.001 – volume: 213 start-page: 434 issue: 5 year: 2015 end-page: 443 ident: CR14 article-title: One-step hydrothermal approach to fabricate carbon dots from apple juice for imaging of mycobacterium and fungal cells ☆ publication-title: Sensors Actuators B Chem doi: 10.1016/j.snb.2015.02.104 – volume: 89 start-page: 459 issue: 3 year: 2015 end-page: 483 ident: CR35 article-title: Mechanisms of acute kidney injury induced by experimental Lonomia obliqua envenomation publication-title: Arch Toxicol doi: 10.1007/s00204-014-1264-0 – volume: 82 start-page: 71 issue: 1 year: 2016 end-page: 80 ident: CR9 article-title: Antibodies against venom of the Snake Deinagkistrodon acutus publication-title: Appl Environ Microbiol doi: 10.1128/AEM.02608-15 – volume: 129 start-page: 263 issue: 3 year: 2012 ident: 3198_CR41 publication-title: Thromb Res doi: 10.1016/j.thromres.2011.10.010 – volume: 30 start-page: 579 issue: 5 year: 2004 ident: 3198_CR43 publication-title: Semin Thromb Hemost doi: 10.1055/s-2004-835678 – volume: 11 start-page: 6703 issue: 7 year: 2017 ident: 3198_CR18 publication-title: ACS Nano doi: 10.1021/acsnano.7b01023 – volume: 46 start-page: S308 year: 2018 ident: 3198_CR22 publication-title: Artif Cells Blood Substitutes Biotechnol – volume-title: Renal involvement in tropical diseases year: 1999 ident: 3198_CR24 – volume: 5 start-page: 6543 issue: 9 year: 2014 ident: 3198_CR13 publication-title: RSC Adv doi: 10.1039/C4RA09546D – volume: 14 start-page: 457 issue: Suppl. 1 year: 2018 ident: 3198_CR26 publication-title: Nat Rev Nephrol doi: 10.1038/s41581-018-0015-5 – volume: 213 start-page: 434 issue: 5 year: 2015 ident: 3198_CR14 publication-title: Sensors Actuators B Chem doi: 10.1016/j.snb.2015.02.104 – volume: 8 start-page: 276 issue: 1 year: 2013 ident: 3198_CR27 publication-title: Nanoscale Res Lett doi: 10.1186/1556-276X-8-276 – volume: 47 start-page: 6695 issue: 23 year: 2011 ident: 3198_CR20 publication-title: Chem Commun (Camb) doi: 10.1039/c1cc11943e – volume: 5 start-page: 594 issue: 10 year: 2013 ident: 3198_CR33 publication-title: N Am J Med Sci doi: 10.4103/1947-2714.120795 – volume: 6 start-page: 865 issue: 6 year: 1994 ident: 3198_CR38 publication-title: Curr Opin Immunol doi: 10.1016/0952-7915(94)90006-X – volume: 59 start-page: 192 issue: 4 year: 2013 ident: 3198_CR16 publication-title: Carbon doi: 10.1016/j.carbon.2013.03.009 – volume: 2014 start-page: 781857 year: 2014 ident: 3198_CR40 publication-title: TheScientificWorldJournal doi: 10.1155/2014/781857 – volume: 23 start-page: 22 year: 2017 ident: 3198_CR7 publication-title: J Venom Anim Toxins Trop Dis doi: 10.1186/s40409-017-0112-0 – volume: 108 start-page: 187 year: 2016 ident: 3198_CR21 publication-title: Biomaterials doi: 10.1016/j.biomaterials.2016.08.047 – volume: 112 start-page: 666 issue: 4 year: 2014 ident: 3198_CR42 publication-title: Thromb Haemost – volume: 68 start-page: 803 issue: 6 year: 2013 ident: 3198_CR44 publication-title: Clinics (Sao Paulo) doi: 10.6061/clinics/2013(06)13 – volume: 126 start-page: 12736 issue: 40 year: 2015 ident: 3198_CR10 publication-title: J Am Chem Soc – volume: 19 start-page: 764 issue: 12 year: 2014 ident: 3198_CR5 publication-title: Nephrology (Carlton) doi: 10.1111/nep.12327 – volume: 30 start-page: 1017 issue: 9 year: 1992 ident: 3198_CR8 publication-title: Toxicon doi: 10.1016/0041-0101(92)90046-8 – volume: 6 start-page: 13817 issue: 22 year: 2014 ident: 3198_CR12 publication-title: Nanoscale doi: 10.1039/C4NR04267K – volume: 49 start-page: 4430 issue: 26 year: 2010 ident: 3198_CR17 publication-title: Angew Chem Int Ed Engl doi: 10.1002/anie.200906154 – volume: 225 start-page: 189 year: 2018 ident: 3198_CR1 publication-title: J Ethnopharmacol doi: 10.1016/j.jep.2018.07.002 – volume: 118 start-page: 105 year: 2018 ident: 3198_CR31 publication-title: Food Chem Toxicol doi: 10.1016/j.fct.2018.05.016 – volume: 6 start-page: 30611 issue: 36 year: 2016 ident: 3198_CR28 publication-title: RSC Adv doi: 10.1039/C5RA27662D – volume: 44 start-page: 942 issue: 3 year: 2007 ident: 3198_CR29 publication-title: Mol Phylogenet Evol doi: 10.1016/j.ympev.2007.05.019 – volume: 63 start-page: 313 issue: 5–6 year: 2000 ident: 3198_CR6 publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.2000.63.313 – volume: 93 start-page: 123 issue: 01 year: 2005 ident: 3198_CR45 publication-title: Toxins Involved Contrib Metalloproteinase-Induced Pulmon Hemorr – volume: 35 start-page: 891 issue: 3 year: 1989 ident: 3198_CR4 publication-title: Kidney Int doi: 10.1038/ki.1989.70 – volume: 14 start-page: 431 issue: 4 year: 2019 ident: 3198_CR15 publication-title: Nanomedicine (Lond) doi: 10.2217/nnm-2018-0285 – volume: 45 start-page: 190 issue: 4 year: 2012 ident: 3198_CR30 publication-title: Med Mol Morphol doi: 10.1007/s00795-011-0559-y – volume: 185 start-page: 1371 issue: 7 year: 1997 ident: 3198_CR39 publication-title: J Exp Med doi: 10.1084/jem.185.7.1371 – volume: 13 start-page: 391 issue: 4 year: 2018 ident: 3198_CR23 publication-title: Nanomedicine (Lond) doi: 10.2217/nnm-2017-0297 – volume: 82 start-page: 71 issue: 1 year: 2016 ident: 3198_CR9 publication-title: Appl Environ Microbiol doi: 10.1128/AEM.02608-15 – volume: 55 start-page: 295 issue: 5 year: 2013 ident: 3198_CR32 publication-title: Rev Inst Med Trop Sao Paulo doi: 10.1590/S0036-46652013000500001 – volume: 89 start-page: 459 issue: 3 year: 2015 ident: 3198_CR35 publication-title: Arch Toxicol doi: 10.1007/s00204-014-1264-0 – volume: 23 start-page: 20 issue: 1 year: 2017 ident: 3198_CR3 publication-title: J Venom Anim Toxins Trop Dis doi: 10.1186/s40409-017-0111-1 – volume: 6 start-page: 10040 issue: 17 year: 2014 ident: 3198_CR11 publication-title: Nanoscale doi: 10.1039/C4NR02657H – volume: 15 start-page: 60 issue: 1 year: 2017 ident: 3198_CR19 publication-title: J Nanobiotechnol doi: 10.1186/s12951-017-0296-z – volume: 85 start-page: 27 year: 2014 ident: 3198_CR34 publication-title: Toxicon doi: 10.1016/j.toxicon.2014.04.001 – volume: 56 start-page: 45 issue: 1 year: 2010 ident: 3198_CR2 publication-title: Toxicon doi: 10.1016/j.toxicon.2010.01.027 – volume: 7 start-page: 1532 issue: 5 year: 2015 ident: 3198_CR37 publication-title: Toxins doi: 10.3390/toxins7051532 – volume: 119 start-page: c131 issue: 2 year: 2011 ident: 3198_CR25 publication-title: Nephron Clin Pract doi: 10.1159/000324228 – volume: 56 start-page: 295 issue: 3 year: 2014 ident: 3198_CR36 publication-title: J Pineal Res doi: 10.1111/jpi.12123 |
| SSID | ssj0047076 |
| Score | 2.4161286 |
| Snippet | Background
As an emerging nanomaterial, carbon dots (CDs) have been the focus of tremendous attention for biomedical applications. However, little information... As an emerging nanomaterial, carbon dots (CDs) have been the focus of tremendous attention for biomedical applications. However, little information is... BackgroundAs an emerging nanomaterial, carbon dots (CDs) have been the focus of tremendous attention for biomedical applications. However, little information... Abstract Background As an emerging nanomaterial, carbon dots (CDs) have been the focus of tremendous attention for biomedical applications. However, little... |
| SourceID | doaj pubmedcentral proquest pubmed crossref springer |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 377 |
| SubjectTerms | Abnormalities Acute kidney injury Biological activity Biomedical materials Carbon Carbon dots Chemistry and Materials Science Creatinine Cytokines Deinagkistrodon acutus Deinagkistrodon acutus venom Drug development Histology Inflammation Interleukins Kidney diseases Kidneys Materials Science Molecular Medicine Monocyte chemoattractant protein 1 Monocytes Nano Express Nanochemistry Nanomaterials Nanoscale Science and Technology Nanotechnology Nanotechnology and Microengineering Phellodendri Chinensis Cortex Carbonisata-carbon dots Protective effect Proteins Pyrolysis Renal function Snake bites Sustainable development Thrombocytopenia Urea Venom |
| SummonAdditionalLinks | – databaseName: Biological Science Database dbid: M7P link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3JbtRAEG1B4EAO7ARDQI3ECdSK20svJxQmRCBQNAeIcrPavQxGyA72TASfwt9S5WXCQMgFaS7jXuSeef26ylV-RchzZ5QRWamYjINlmfQJ04nImeEOAJAay_vo-fEHeXSkTk70fHzg1o1plRMn9kTtGovPyPfg5EdnRer81ek3hlWjMLo6ltC4Sq6hSkLap-7NJybOZNwXlwMbhTOZy3SManIl9jqMP6AjrYGFNDhSG-dSL99_kc35d-rkH_HT_lg6vPW_C7pNbo4GKd0fEHSHXPH1XbL9m0zhPfJzPog5ADHSQe24o02gM9OWTU0PGvh6AF3PvKP4tgqdY3JpA4Tm2opigW5Mku_oDPN6v4_DMIvIULMwFdinMLyqzQJtWeBzmNPY1XLV0WNfA4VjdRELc-_DRU_fV672P-i7-gug4T75dPjm4-wtG0s6MJuLbMlSK11I0pDH1seiVAAUjnI20oIlkuYhAd6W1njuQxackzbm3ps0LaUrkwAH7gOyVTe1f0hoHryTZTClACvIhKRMpAqxLmHWgNHbiMTTH1rYUe8cy258LXq_R4liwEABGCgQAwWPyIv1kNNB7OOyzq8RJeuOqNPdX2jaRTFu-0KkQQlrHVdGZzbnKmgPHzAB0HfVPiK7EziKkTy64hwZFzYjaUqEexaRZ-tmYAUM9ZjaN6thCp3xGKfYGRC7vlFg8QxlEyMiN7C8sZLNlrr63CuPC83R4o_Iywn157f1zx_q0eVrfExuJLgNecK42CVby3bln5Dr9mxZde3TfkP_ArijU8M priority: 102 providerName: ProQuest |
| Title | Protective Effects of Carbon Dots Derived from Phellodendri Chinensis Cortex Carbonisata against Deinagkistrodon acutus Venom-Induced Acute Kidney Injury |
| URI | https://link.springer.com/article/10.1186/s11671-019-3198-1 https://www.ncbi.nlm.nih.gov/pubmed/31845094 https://www.proquest.com/docview/2327211795 https://www.proquest.com/docview/3196712154 https://www.proquest.com/docview/2327941095 https://pubmed.ncbi.nlm.nih.gov/PMC6915193 https://doaj.org/article/63f86ccd18a94c518f9ef9e99004269e |
| Volume | 14 |
| WOSCitedRecordID | wos000509988800002&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 1556-276X dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0047076 issn: 1931-7573 databaseCode: DOA dateStart: 20060101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVPQU databaseName: Biological Science Database customDbUrl: eissn: 1556-276X dateEnd: 20191231 omitProxy: false ssIdentifier: ssj0047076 issn: 1931-7573 databaseCode: M7P dateStart: 20160101 isFulltext: true titleUrlDefault: http://search.proquest.com/biologicalscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: Materials Science Database (ProQuest) customDbUrl: eissn: 1556-276X dateEnd: 20191231 omitProxy: false ssIdentifier: ssj0047076 issn: 1931-7573 databaseCode: KB. dateStart: 20160101 isFulltext: true titleUrlDefault: http://search.proquest.com/materialsscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1556-276X dateEnd: 20191231 omitProxy: false ssIdentifier: ssj0047076 issn: 1931-7573 databaseCode: BENPR dateStart: 20160101 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: Publicly Available Content Database customDbUrl: eissn: 1556-276X dateEnd: 20191231 omitProxy: false ssIdentifier: ssj0047076 issn: 1931-7573 databaseCode: PIMPY dateStart: 20160101 isFulltext: true titleUrlDefault: http://search.proquest.com/publiccontent providerName: ProQuest |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9NAEF5B4QAHxLMYSrRInECmXj_2cWzSVlSFyEJQhZO13kcxquwqTir4KfxbZmwnNFDgghRFine9sndmv_1WM_mGkBdWS83TUoYi8iZMhYtDFfMs1MyCAyTasC56fvJWTKdyNlP5pVJfmBPWywP3E7fLEy-5MZZJrVKTMemVgw-AKLJ_5RB9gfWsDlM9Bqci6srKATthochEMsQzmeS7LUYe8AitAH8UHKE2dqROuP8qtvl70uQvkdNuQzq8S-4MTJLu9W9wj1xz9X1y-5K-4APyPe9VGADRaC9T3NLG04mel01N9xv4uQ9dL5yl-DcTmmNWaANIZOcVxcramN3e0gkm5H4dbsP0H031qa6AWMLtVa1PkYQCEMOY2iwXy5aeuBqwF8uCGBh7Dy46elzZ2n2jR_UXMOND8vHw4MPkTTjUYghNxtNFmBhhfZz4LDIu4qUECzPUoREGKESS-RgAVxjtmPOpt1aYiDmnk6QUtow97JSPyFbd1O4xoZl3VpRelxzoi_ZxGQvpI1XCqB7DrgGJVvYozCBUjvUyzoruwCJ50ZuwABMWaMKCBeTl-pbzXqXjb53HaOR1RxTY7i6A2xWD2xX_cruA7KxcpBhWfVsAO8UDtVDZlc2IdgLVPNKAPF83w3LGGI2uXbPsh1Api3CI7d7h1g8K8Jui3mFAxIYrbrzJZktdfe4kw7liSNUD8mrltD8f648T9eR_TNRTcivGtcbikPEdsrWYL90zctNcLKp2PiLXxUyOyI3xwTR_P-rWMHwfj1-PMAk3h5b86F3-6QdSn0uy |
| linkProvider | Directory of Open Access Journals |
| linkToHtml | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1LbxMxELZKigQceD8WChgJLqBV1_vy7gGhklA1SlrlUKpyMl4_wiK0W7JJoT-FP8FvZGYfKYHSWw9IuWRtj7zO529mMvYMIc-1TGQcZonLPavckBvfTf04ciXTAIBAKlZHzw_GfG8vOTxMJ2vkZ3cXBo9VdpxYE7UuFf5HvgmaH50VnkZvjr66WDUKo6tdCY0GFiNz8g1ctur1cAC_7wvf3363399x26oCroricO4GimvrBzbylPHiLIG5MsyowhUowyCyPlAHV9IwY0OrNVceM0YGQcZ15lvgfJB7iayHAPakR9Ynw93Jh477Q-7V5ezAKmIuj3jQxlFZEm9WGPFA1z0F3kvBdVvRhHXBgLOs3L8Pa_4Rsa0V4faN_20Jb5LrrclNt5o9cousmeI2ufZbIsY75MekSVcB1E-bfM4VLS3ty1lWFnRQwtcBdD02muJ9HDrB47MlULae5RRLkOM1gIr28eTy93YYnpOSVE5lDhY4DM8LOUVrHTQWyJRqMV9U9MAUoKSwfooC2Vvw0NBRrgtzQofFZ8D7XfL-QtbmHukVZWEeEBpZo3lmZRaDnSetn_k8sV6agVSL8WmHeB2AhGozumNhkS-i9uySWDSYE4A5gZgTzCEvl0OOmnQm53V-i6hcdsRM5PWDcjYVLbGJOLBJrJRmiUxDFbHEpgY-YOSgd54ah2x0YBQtPVbiFIlnNqNa4Jj2JHTIs2Uz8B4Gs2RhykUjIg2ZhyLuNztkOVHQUyEmhnQIX9k7K2-y2lLkn-rc6nHK0KdxyKtul51O658L9fD8d3xKruzs747FeLg3ekSu-kgBzHdZvEF689nCPCaX1fE8r2ZPWjqh5ONFb79fzzmzAQ |
| linkToPdf | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9NAEF6VghAceD8MBRYJLiArXr_We0CoJEREqaIcoOrNrPcRjJBd7KTQn8Jf4dcx40dKoPTWA1Iu8e6O1pt5Zma_IeSZlomMwyxxuWeVG3Lju8KPI1cyDQwQSMWa7Pn-Hp_NkoMDMd8iP_u7MFhW2evERlHrUuF_5AOw_BiscBENbFcWMR-NXx9-dbGDFGZa-3YaLYtMzfE3CN_qV5MR_NbPfX_89v3wndt1GHBVFIdLN1BcWz-wkaeMF2cJ7JshugpXYBiDyPqgRriShhkbWq258pgxMggyrjPfgv4HuhfIRY6g5U3Z4Ly3AiH3msZ24B8xl0c86DKqLIkHNeY-MIgXoAEFBHEbNrFpHXCav_t32eYfudvGJI6v_8-HeYNc6xxxuttKzk2yZYpb5Opv8Iy3yY95C2IBBoG2KM81LS0dyiorCzoq4esIph4ZTfGWDp1jUW0JilxXOcXG5Hg5oKZDrGf-3i3D6ilJ5ULm4JfD8ryQC_ThwY4BTalWy1VN900Bpgu7qiigvQsPDZ3mujDHdFJ8Bim4Qz6cy9ncJdtFWZj7hEbWaJ5ZmcXg_UnrZz5PrCcyoGoxa-0Qr2emVHU479hu5EvaxHtJnLb8lwL_pch_KXPIi_WSwxbk5KzJb5BD1xMRn7x5UFaLtFN3aRzYJFZKs0SKUEUsscLAB1wfjNmFcchOz5hppzTr9IQrTx1GY8ERDCV0yNP1MGhDTHHJwpSrloQImYck7rXSst4oWK8Q4SIdwjfkaONNNkeK_FODuB4LhpGOQ172EneyrX8e1IOz3_EJuQwyl-5NZtOH5IqP2oD5Lot3yPayWplH5JI6WuZ19bjRK5R8PG_Z-wW-HrpA |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Protective+Effects+of+Carbon+Dots+Derived+from+Phellodendri+Chinensis+Cortex+Carbonisata+against+Deinagkistrodon+acutus+Venom-Induced+Acute+Kidney+Injury&rft.jtitle=Nanoscale+research+letters&rft.au=Zhang%2C+Meiling&rft.au=Cheng%2C+Jinjun&rft.au=Sun%2C+Ziwei&rft.au=Kong%2C+Hui&rft.date=2019-12-16&rft.issn=1931-7573&rft.volume=14&rft.issue=1&rft.spage=377&rft_id=info:doi/10.1186%2Fs11671-019-3198-1&rft_id=info%3Apmid%2F31845094&rft.externalDocID=31845094 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1931-7573&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1931-7573&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1931-7573&client=summon |