p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents

The Mitogen Activated Protein Kinase (MAPK) signaling plays a critical role in the outcome and the sensitivity to anticancer therapies. Activated MAPK can transmit extracellular signals to regulate cell growth, proliferation, differentiation, migration, apoptosis and so on. Apoptosis as well as macr...

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Bibliographic Details
Published in:	Cancer letters Vol. 344; no. 2; pp. 174 - 179
Main Authors:	Sui, Xinbing, Kong, Na, Ye, Li, Han, Weidong, Zhou, Jichun, Zhang, Qin, He, Chao, Pan, Hongming
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier Ireland Ltd 28.03.2014 Elsevier Limited
Subjects:	Antineoplastic Agents - pharmacology Apoptosis Apoptosis - drug effects Apoptosis - physiology Autophagy Autophagy - drug effects Autophagy - physiology Cancer Cancer therapies Chemoresistance Hematology, Oncology and Palliative Medicine Humans JNK Kinases MAP Kinase Kinase 4 - metabolism MAP Kinase Signaling System - drug effects MAP Kinase Signaling System - physiology Neoplasms - drug therapy Neoplasms - enzymology Neoplasms - pathology P38 p38 Mitogen-Activated Protein Kinases - metabolism P38 Autophagy JNK Chemoresistance Apoptosis
ISSN:	0304-3835, 1872-7980, 1872-7980
Online Access:	Get full text
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