The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation

We have determined the three-dimensional (3D) architecture of the Caulobacter crescentus genome by combining genome-wide chromatin interaction detection, live-cell imaging, and computational modeling. Using chromosome conformation capture carbon copy (5C), we derive ~13 kb resolution 3D models of th...

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Bibliographic Details

Published in:	Molecular cell Vol. 44; no. 2; p. 252
Main Authors:	Umbarger, Mark A, Toro, Esteban, Wright, Matthew A, Porreca, Gregory J, Baù, Davide, Hong, Sun-Hae, Fero, Michael J, Zhu, Lihua J, Marti-Renom, Marc A, McAdams, Harley H, Shapiro, Lucy, Dekker, Job, Church, George M
Format:	Journal Article
Language:	English
Published:	United States 21.10.2011
Subjects:	Caulobacter crescentus - genetics Chromatin - physiology Chromosome Segregation - physiology Chromosomes, Bacterial - physiology Computer Simulation Genome, Bacterial
ISSN:	1097-4164, 1097-4164
Online Access:	Get more information
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