Role of Human Epicardial Adipose Tissue-Derived miR-92a-3p in Myocardial Redox State

Visceral obesity is directly linked to increased cardiovascular risk, including heart failure. This study explored the ability of human epicardial adipose tissue (EAT)-derived microRNAs (miRNAs) to regulate the myocardial redox state and clinical outcomes. This study screened for miRNAs expressed an...

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Veröffentlicht in:	Journal of the American College of Cardiology Jg. 82; H. 4; S. 317
Hauptverfasser:	Carena, Maria Cristina, Badi, Ileana, Polkinghorne, Murray, Akoumianakis, Ioannis, Psarros, Costas, Wahome, Elizabeth, Kotanidis, Christos P, Akawi, Nadia, Antonopoulos, Alexios S, Chauhan, Jagat, Sayeed, Rana, Krasopoulos, George, Srivastava, Vivek, Farid, Shakil, Walcot, Nicholas, Douglas, Gillian, Channon, Keith M, Casadei, Barbara, Antoniades, Charalambos
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 25.07.2023
Schlagworte:	Adipose Tissue - metabolism Animals Genome-Wide Association Study Humans Mice Mice, Transgenic MicroRNAs - genetics MicroRNAs - metabolism Myocardium - metabolism Oxidation-Reduction Wnt5a signaling microRNAs epicardial adipose tissue myocardial NADPH oxidase activity myocardial oxidative stress
ISSN:	1558-3597, 1558-3597
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