Multi-generational impacts of arsenic exposure on genome-wide DNA methylation and the implications for arsenic-induced skin lesions

As a nonmutagenic human carcinogen, arsenic (As)'s carcinogenic activity is likely the result of epigenetic changes, particularly alterations in DNA methylation. While increasing studies indicate a potentially important role for timing of As exposure on DNA methylation patterns and the subseque...

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Bibliographic Details
Published in:Environment international Vol. 119; pp. 250 - 263
Main Authors: Guo, Xiaojuan, Chen, Xushen, Wang, Jie, Liu, Zhiyue, Gaile, Daniel, Wu, Hongmei, Yu, Guan, Mao, Guangyun, Yang, Zuopeng, Di, Zhen, Guo, Xiuqing, Cao, Li, Chang, Peiye, Kang, Binxian, Chen, Jinyu, Gao, Wen, Ren, Xuefeng
Format: Journal Article
Language:English
Published: Netherlands Elsevier Ltd 01.10.2018
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ISSN:0160-4120, 1873-6750, 1873-6750
Online Access:Get full text
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