Highly Pathogenic Avian Influenza Virus (H5N8) Clade 2.3.4.4 Infection in Migratory Birds, Egypt

We isolated highly pathogenic avian influenza virus (H5N8) of clade 2.3.4.4 from the common coot (Fulica atra) in Egypt, documenting its introduction into Africa through migratory birds. This virus has a close genetic relationship with subtype H5N8 viruses circulating in Europe. Enhanced surveillanc...

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Published in:Emerging infectious diseases Vol. 23; no. 6; pp. 1048 - 1051
Main Authors: Selim, Abdullah A., Erfan, Ahmed M., Hagag, Naglaa, Zanaty, Ali, Samir, Abdel-Hafez, Samy, Mohamed, Abdelhalim, Ahmed, Arafa, Abdel-Satar A., Soliman, Mohamed A., Shaheen, Momtaz, Ibraheem, Essam M., Mahrous, Ibrahim, Hassan, Mohamed K., Naguib, Mahmoud M.
Format: Journal Article
Language:English
Published: United States U.S. National Center for Infectious Diseases 01.06.2017
Centers for Disease Control and Prevention
Subjects:
Amino Acid Sequence
Animal Migration - physiology
Animals
Animals, Wild
Avian influenza viruses
Birds
clade 2.3.4.4
Egypt
Egypt - epidemiology
Gene Expression
Hemagglutinin Glycoproteins, Influenza Virus - chemistry
Hemagglutinin Glycoproteins, Influenza Virus - genetics
Hemagglutinin Glycoproteins, Influenza Virus - metabolism
highly pathogenic avian influenza
influenza
Influenza A Virus, H5N8 Subtype - classification
Influenza A Virus, H5N8 Subtype - genetics
Influenza A Virus, H5N8 Subtype - isolation & purification
Influenza A Virus, H5N8 Subtype - pathogenicity
Influenza in Birds - epidemiology
Influenza in Birds - transmission
Influenza in Birds - virology
Migratory birds
Models, Molecular
Mutation
Phylogeny
Physiological aspects
Protein Conformation, alpha-Helical
Protein Conformation, beta-Strand
Reassortant Viruses - classification
Reassortant Viruses - genetics
Reassortant Viruses - isolation & purification
Reassortant Viruses - pathogenicity
Research Letter
subtype H5N8
Egypt
influenza
highly pathogenic avian influenza
viruses
subtype H5N8
Africa
Egypt
clade 2.3.4.4
zoonoses
migratory birds
ISSN:1080-6040, 1080-6059, 1080-6059
Online Access:Get full text
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Summary:We isolated highly pathogenic avian influenza virus (H5N8) of clade 2.3.4.4 from the common coot (Fulica atra) in Egypt, documenting its introduction into Africa through migratory birds. This virus has a close genetic relationship with subtype H5N8 viruses circulating in Europe. Enhanced surveillance to detect newly emerging viruses is warranted.
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ISSN:1080-6040
1080-6059
1080-6059
DOI:10.3201/eid2306.162056