An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer

Mechanisms of therapeutic resistance and vulnerability evolve in metastatic cancers as tumor cells and extrinsic microenvironmental influences change during treatment. To support the development of methods for identifying these mechanisms in individual people, here we present an omic and multidimens...

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Veröffentlicht in:	Cell reports. Medicine Jg. 3; H. 2; S. 100525
Hauptverfasser:	Johnson, Brett E., Creason, Allison L., Stommel, Jayne M., Keck, Jamie M., Parmar, Swapnil, Betts, Courtney B., Blucher, Aurora, Boniface, Christopher, Bucher, Elmar, Burlingame, Erik, Camp, Todd, Chin, Koei, Eng, Jennifer, Estabrook, Joseph, Feiler, Heidi S., Heskett, Michael B., Hu, Zhi, Kolodzie, Annette, Kong, Ben L., Labrie, Marilyne, Lee, Jinho, Leyshock, Patrick, Mitri, Souraya, Patterson, Janice, Riesterer, Jessica L., Sivagnanam, Shamilene, Somers, Julia, Sudar, Damir, Thibault, Guillaume, Weeder, Benjamin R., Zheng, Christina, Nan, Xiaolin, Thompson, Reid F., Heiser, Laura M., Spellman, Paul T., Thomas, George, Demir, Emek, Chang, Young Hwan, Coussens, Lisa M., Guimaraes, Alexander R., Corless, Christopher, Goecks, Jeremy, Bergan, Raymond, Mitri, Zahi, Mills, Gordon B., Gray, Joe W.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Inc 15.02.2022 Elsevier
Schlagworte:	Advanced Basic Science Biopsy Breast Neoplasms - genetics Female human tumor atlas Humans metastatic breast cancer personalized medicine precision oncology Tumor Microenvironment - genetics precision oncology human tumor atlas metastatic breast cancer personalized medicine
ISSN:	2666-3791, 2666-3791
Online-Zugang:	Volltext
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