Personalized EEG-guided brain stimulation targeting in major depression via network controllability and multi-objective optimization

Background Major depressive disorder (MDD) is associated with widespread disruptions in brain network dynamics. Although noninvasive brain stimulation (NIBS) has shown promise as an alternative treatment, its efficacy remains limited due to a lack of individualized targeting strategies that account...

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Bibliographic Details
Published in:	BMC psychiatry Vol. 25; no. 1; pp. 723 - 11
Main Authors:	Wang, Aihua, Sun, Jingnan
Format:	Journal Article
Language:	English
Published:	London BioMed Central 23.07.2025 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Adult Algorithms Brain - physiopathology Brain network controllability Brain research Case-Control Studies Depressive Disorder, Major - physiopathology Depressive Disorder, Major - therapy EEG Electroencephalography Electroencephalography - methods Embedding Female Frequency dependence Humans Major depressive disorder Male Mathematical optimization Medicine Medicine & Public Health Mental depression Mental disorders Middle Aged Nerve Net - physiopathology Neural networks Neuromodulation Neurophysiology Noninvasive brain stimulation for mental disorders Optimization Personalized stimulation Precision Medicine - methods Psychiatry Psychotherapy Research methodology Time series Transcranial magnetic stimulation Personalized stimulation EEG Brain network controllability Major depressive disorder
ISSN:	1471-244X, 1471-244X
Online Access:	Get full text
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