Incidence and predictors of oral feeding intolerance in acute pancreatitis: A systematic review, meta-analysis, and meta-regression

Tolerance of oral food is an important criterion for hospital discharge in patients with acute pancreatitis. Patients who develop oral feeding intolerance have prolonged hospitalisation, use additional healthcare resources, and have impaired quality of life. This study aimed to quantify the incidenc...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Clinical nutrition (Edinburgh, Scotland) Ročník 36; číslo 3; s. 722 - 729
Hlavní autoři: Bevan, Melody G., Asrani, Varsha M., Bharmal, Sakina, Wu, Landy M., Windsor, John A., Petrov, Maxim S.
Médium: Journal Article
Jazyk:angličtina
Vydáno: England Elsevier Ltd 01.06.2017
Témata:
Acute Disease
Acute pancreatitis
blood serum
carboxylic ester hydrolases
Enteral Nutrition
etiology
Gastroenterology and Hepatology
health services
hospitals
Humans
Incidence
meta-analysis
Nutrition
Observational Studies as Topic
Oral feeding intolerance
pancreatitis
Pancreatitis - therapy
patients
Predictors
quality of life
Randomized Controlled Trials as Topic
refeeding
risk
systematic review
World Health Organization
Acute pancreatitis
Nutrition
Oral feeding intolerance
Predictors
Incidence
ISSN:0261-5614, 1532-1983, 1532-1983
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:Tolerance of oral food is an important criterion for hospital discharge in patients with acute pancreatitis. Patients who develop oral feeding intolerance have prolonged hospitalisation, use additional healthcare resources, and have impaired quality of life. This study aimed to quantify the incidence of oral feeding intolerance, the effect of confounders, and determine the best predictors of oral feeding intolerance. Clinical studies indexed in three electronic databases (EMBASE, MEDLINE, and the Cochrane Central Register of Controlled Trials) were reviewed. Incidence and predictor data were meta-analysed and possible confounders were investigated by meta-regression analysis. A total of 22 studies with 2024 patients met the inclusion criteria, 17 of which (with 1550 patients) were suitable for meta-analysis. The incidence of oral feeding intolerance was 16.3%, and was not affected by WHO region, age, sex, or aetiology of acute pancreatitis. Nine of the 22 studies investigated a total of 62 different predictors of oral feeding intolerance. Serum lipase level prior to refeeding, pleural effusions, (peri)pancreatic collections, Ranson score, and Balthazar score were found to be statistically significant in meta-analyses. Oral feeding intolerance affects approximately 1 in 6 patients with acute pancreatitis. Serum lipase levels of more than 2.5 times the upper limit of normal prior to refeeding is a potentially useful threshold to identify patients at high risk of developing oral feeding intolerance.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ObjectType-Undefined-4
ISSN:0261-5614
1532-1983
1532-1983
DOI:10.1016/j.clnu.2016.06.006