Pneumococcal infection in adults: burden of disease

To overview the present global burden of pneumococcal disease is important because new preventive measures such as the pneumococcal conjugate vaccine 13 are currently being evaluated. Pneumococcal disease is roughly divided into non-invasive and invasive disease. The burden of non-invasive pneumococ...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Clinical microbiology and infection Ročník 20; číslo s5; s. 45 - 51
Hlavní autoři: Drijkoningen, J.J.C., Rohde, G.G.U.
Médium: Journal Article
Jazyk:angličtina
Vydáno: England Elsevier Ltd 01.05.2014
Elsevier Limited
Témata:
Adult
Community-Acquired Infections - economics
Community-Acquired Infections - epidemiology
Community-acquired pneumonia
Comorbidity
Disease
disease burden
Disease prevention
elderly
Epidemiology
Health risks
Humans
Incidence
invasive pneumococcal disease
Meningitis
Mortality
Mortality risk
outcome
pneumococcal conjugate vaccine
Pneumococcal Infections - economics
Pneumococcal Infections - epidemiology
pneumococcal pneumonia
Pneumococcal Vaccines - therapeutic use
Pneumonia
Streptococcus pneumoniae
Vaccination
Vaccines
Vaccines, Conjugate - therapeutic use
pneumococcal pneumonia
elderly
invasive pneumococcal disease
Community-acquired pneumonia
disease burden
incidence
outcome
pneumococcal conjugate vaccine
Streptococcus pneumoniae
ISSN:1198-743X, 1469-0691, 1469-0691
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:To overview the present global burden of pneumococcal disease is important because new preventive measures such as the pneumococcal conjugate vaccine 13 are currently being evaluated. Pneumococcal disease is roughly divided into non-invasive and invasive disease. The burden of non-invasive pneumococcal disease in adults is mainly determined by community-acquired pneumonia. Pneumococcal pneumonia has high incidence rates and carries a high mortality risk, especially in the elderly. Within the cluster of invasive pneumococcal diseases, pneumonia also represents the most common infectious source. Incidence and mortality rates of both non-invasive and invasive disease have changed as a result of pneumococcal vaccination in children. However, especially elderly patients with comorbidities remain vulnerable to morbidity and mortality caused by pneumococcal disease. The current review summarizes the current knowledge on the epidemiology including outcome of the main clinical forms of pneumococcal disease, with a special focus on elderly patients. Furthermore, the economic burden and future vaccine strategies are briefly discussed.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
ObjectType-Article-2
ObjectType-Feature-1
ISSN:1198-743X
1469-0691
1469-0691
DOI:10.1111/1469-0691.12461