Pattern recognition receptors and the inflammasome in kidney disease

Key Points Toll-like receptors (TLRs), nucleotide-binding oligomerization domain receptors (NLRs) and the NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome regulate inflammatory and repair processes in the kidneys TLRs prevent invasion and growth of pathogens in the urinary tract...

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Bibliographic Details
Published in:	Nature reviews. Nephrology Vol. 10; no. 7; pp. 398 - 414
Main Authors:	Leemans, Jaklien C., Kors, Lotte, Anders, Hans-Joachim, Florquin, Sandrine
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.07.2014 Nature Publishing Group
Subjects:	692/420/254 692/420/256 692/699/1585/1681 692/699/1585/4 Acute Kidney Injury - microbiology Acute Kidney Injury - physiopathology Adaptor Proteins, Signal Transducing - physiology Animals Carrier Proteins - immunology Cell receptors Cytokines Development and progression Genetic aspects Homeostasis Humans Immune response Infections Inflammasomes - immunology Inflammation Kidney - immunology Kidney diseases Kidney Diseases - immunology Kidney Transplantation Kinases Medical research Medicine & Public Health Medicine, Experimental Mice Nephrology NLR Family, Pyrin Domain-Containing 3 Protein Pathogens Pathology Pattern recognition Properties Proteins Receptors, Pattern Recognition - immunology review-article Sepsis - complications Toll-Like Receptors - genetics Toll-Like Receptors - immunology Urinary Tract Infections - immunology Urogenital system
ISSN:	1759-5061, 1759-507X, 1759-507X
Online Access:	Get full text
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