Invited review: human air-liquid-interface organotypic airway tissue models derived from primary tracheobronchial epithelial cells—overview and perspectives

The lung is an organ that is directly exposed to the external environment. Given the large surface area and extensive ventilation of the lung, it is prone to exposure to airborne substances, such as pathogens, allergens, chemicals, and particulate matter. Highly elaborate and effective mechanisms ha...

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Bibliographic Details
Published in:	In vitro cellular & developmental biology. Animal Vol. 57; no. 2; pp. 104 - 132
Main Authors:	Cao, Xuefei, Coyle, Jayme P., Xiong, Rui, Wang, Yiying, Heflich, Robert H., Ren, Baiping, Gwinn, William M., Hayden, Patrick, Rojanasakul, Liying
Format:	Journal Article
Language:	English
Published:	Germany Springer Science & Business Media LLC 01.02.2021 Society for In Vitro Biology Springer US
Subjects:	Air pollution Allergens Animal models Biocompatibility breathing Cigarette smoke cigarettes electronic equipment Epithelial cells epithelium Exposure Gases Homeostasis human health humans Inhalation inhalation exposure INVITED REVIEW Lungs Mechanical ventilation Nanomaterials Nanotechnology Particulate emissions Particulate matter Particulates Pathogens Respiration Respiratory diseases Respiratory system Respiratory tract smoke Smoking Standardization surface area toxic substances Toxicants Toxicity Toxicology Vapors Air-liquid-interface (ALI) airway cultures Pulmonary drug testing Pathogen-host interaction Exposure system Inhalation toxicology
ISSN:	1071-2690, 1543-706X, 1543-706X
Online Access:	Get full text
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