Facilitated diffusion with DNA coiling

When DNA-binding proteins search for their specific binding site on a DNA molecule they alternate between linear 1-dimensional diffusion along the DNA molecule, mediated by nonspecific binding, and 3-dimensional volume excursion events between successive dissociation from and rebinding to DNA. If th...

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Vydané v:	Proceedings of the National Academy of Sciences - PNAS Ročník 106; číslo 20; s. 8204
Hlavní autori:	Lomholt, Michael A, van den Broek, Bram, Kalisch, Svenja-Marei J, Wuite, Gijs J L, Metzler, Ralf
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 19.05.2009
Predmet:	Diffusion DNA - chemistry DNA-Binding Proteins - metabolism Models, Molecular Nucleic Acid Conformation Protein Binding
ISSN:	1091-6490, 1091-6490
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