Clinical Burden and Healthcare Resource Utilization Associated With Managing Transfusion-dependent β-Thalassemia in England

•Endocrine complications are common in transfusion-dependent β-thalassemia.•Use of healthcare resources is high in transfusion-dependent β-thalassemia compared to matched general population controls.•Patients received a mean of 13.62 red blood cell transfusions per year. Patients with transfusion-de...

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Bibliographic Details
Published in:	Clinical therapeutics Vol. 47; no. 1; pp. 37 - 43
Main Authors:	Udeze, Chuka, Ly, Nelly F., Ingleby, Fiona C., Fleming, Sophia D., Conner, Sarah C., Howard, Jo, Li, Nanxin, Shah, Farrukh
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.01.2025 Elsevier Limited
Subjects:	Adolescent Adult Age beta-Thalassemia - complications beta-Thalassemia - economics beta-Thalassemia - mortality beta-Thalassemia - therapy Blood diseases Blood Transfusion Bone diseases Cell survival Chelation Chelation therapy Child Child, Preschool Clinical complications Cost of Illness Databases, Factual Demographics Diabetes mellitus Diagnosis Disease management DNA nucleotidylexotransferase Economics England - epidemiology Erythrocyte Transfusion - economics Erythrocytes Erythropoiesis Ethnicity Fatalities Female Health care Health services utilization Healthcare resource utilization Hemoglobin Humans Hypopituitarism Internal Medicine Iron Iron Chelating Agents - therapeutic use Longitudinal Studies Male Medical diagnosis Medical records Middle Aged Mortality Osteoporosis Patient Acceptance of Health Care - statistics & numerical data Patients Population Primary care Resource utilization Retrospective Studies Socioeconomic factors Socioeconomic status Survival analysis Thalassemia Transfusion-dependent β-thalassemia Young Adult England United Kingdom > UK Economics CPRD IMD TDT Mortality Transfusion-dependent β-thalassemia RBCT PPPY Clinical complications SD HES Healthcare resource utilization HCRU per patient per year red blood cell transfusion Index of Multiple Deprivation Hospital Episode Statistics Clinical Practice Research Datalink standard deviation
ISSN:	0149-2918, 1879-114X, 1879-114X
Online Access:	Get full text
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