Detecting and estimating contamination of human DNA samples in sequencing and array-based genotype data

DNA sample contamination is a serious problem in DNA sequencing studies and may result in systematic genotype misclassification and false positive associations. Although methods exist to detect and filter out cross-species contamination, few methods to detect within-species sample contamination are...

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Bibliographic Details

Published in:	American journal of human genetics Vol. 91; no. 5; p. 839
Main Authors:	Jun, Goo, Flickinger, Matthew, Hetrick, Kurt N, Romm, Jane M, Doheny, Kimberly F, Abecasis, Gonçalo R, Boehnke, Michael, Kang, Hyun Min
Format:	Journal Article
Language:	English
Published:	United States 02.11.2012
Subjects:	Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - genetics DNA Contamination Genotype Humans Sequence Analysis, DNA
ISSN:	1537-6605, 1537-6605
Online Access:	Get more information
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