14-3-3: A Case Study in PPI Modulation

In recent years, targeting the complex network of protein–protein interactions (PPIs) has been identified as a promising drug-discovery approach to develop new therapeutic strategies. 14-3-3 is a family of eukaryotic conserved regulatory proteins which are of high interest as potential targets for p...

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Bibliographic Details
Published in:	Molecules (Basel, Switzerland) Vol. 23; no. 6; p. 1386
Main Authors:	Ballone, Alice, Centorrino, Federica, Ottmann, Christian
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 08.06.2018 MDPI
Subjects:	14-3-3 PPIs 14-3-3 Proteins - metabolism 14-3-3 Proteins - physiology Amino acids Binding sites Bioinformatics Case studies Cell adhesion & migration Cell cycle Crystallography Humans Ligands Pathogenesis Peptides Physiology PPI modulation Protein Interaction Maps - physiology Proteins Regulation Review Signal transduction small molecules small molecules 14-3-3 PPIs PPI modulation
ISSN:	1420-3049, 1420-3049
Online Access:	Get full text
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