Role of dietary fiber in promoting immune health—An EAACI position paper

Microbial metabolism of specific dietary components, such as fiber, contributes to the sophisticated inter‐kingdom dialogue in the gut that maintains a stable environment with important beneficial physiological, metabolic, and immunological effects on the host. Historical changes in fiber intake may...

Full description

Saved in:
Bibliographic Details
Published in:Allergy (Copenhagen) Vol. 77; no. 11; pp. 3185 - 3198
Main Authors: Venter, Carina, Meyer, Rosan W., Greenhawt, Matthew, Pali‐Schöll, Isabella, Nwaru, Bright, Roduit, Caroline, Untersmayr, Eva, Adel‐Patient, Karine, Agache, Ioana, Agostoni, Carlo, Akdis, Cezmi A., Feeney, Mary, Hoffmann‐Sommergruber, Karin, Lunjani, Nonhlanhla, Grimshaw, Kate, Reese, Imke, Smith, Peter K., Sokolowska, Milena, Vassilopoulou, Emilia, Vlieg‐Boerstra, Berber, Amara, Shriya, Walter, Jens, O'Mahony, Liam
Format: Journal Article
Language:English
Published: Denmark Blackwell Publishing Ltd 01.11.2022
Wiley
Subjects:
Allergic diseases
Allergic rhinitis
allergy
Arbetsmedicin och miljömedicin
Asthma
Atopic dermatitis
cell differentiation
Decision making
Dermatitis, Atopic - prevention & control
diet
Dietary Fiber
digestive system
Eczema
fiber
Folkhälsovetenskap, global hälsa och socialmedicin
Gastrointestinal Microbiome
Humans
Hypersensitivity
Immunology
Immunoregulation
ingredients
Intestinal microflora
intestinal microorganisms
Life Sciences
Meta-analysis
Metabolism
Metabolites
microbiome
Microbiomes
nutrition
Nutrition and Dietetics
Näringslära och dietkunskap
Occupational Health and Environmental Health
Prebiotics
Public Health, Global Health and Social Medicine
Rhinitis, Allergic
risk
allergy
prebiotics
fiber
nutrition
diet
allergy, diet, fiber, nutrition, prebiotics
ISSN:0105-4538, 1398-9995, 1398-9995
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Microbial metabolism of specific dietary components, such as fiber, contributes to the sophisticated inter‐kingdom dialogue in the gut that maintains a stable environment with important beneficial physiological, metabolic, and immunological effects on the host. Historical changes in fiber intake may be contributing to the increase of allergic and hypersensitivity disorders as fiber‐derived metabolites are evolutionarily hardwired into the molecular circuitry governing immune cell decision‐making processes. In this review, we highlight the importance of fiber as a dietary ingredient, its effects on the microbiome, its effects on immune regulation, the importance of appropriate timing of intervention to target any potential window of opportunity, and potential mechanisms for dietary fibers in the prevention and management of allergic diseases. In addition, we review the human studies examining fiber or prebiotic interventions on asthma and respiratory outcomes, allergic rhinitis, atopic dermatitis, and overall risk of atopic disorders. While exposures, interventions, and outcomes were too heterogeneous for meta‐analysis, there is significant potential for using fiber in targeted manipulations of the gut microbiome and its metabolic functions in promoting immune health.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Article-2
ObjectType-Feature-1
ObjectType-Review-3
content type line 23
ISSN:0105-4538
1398-9995
1398-9995
DOI:10.1111/all.15430