Recent advances in biotechnological production of 2-phenylethanol

2-Phenylethanol (2-PE) is an important aromatic alcohol with a rose-like fragrance. It has been widely applied in the cosmetic, perfume, and food industries and is mainly produced by chemical synthesis. An alternative method for the production of natural flavors and fragrances is the microbial trans...

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Bibliographic Details
Published in:Biotechnology advances Vol. 29; no. 6; pp. 654 - 660
Main Authors: Hua, Dongliang, Xu, Ping
Format: Journal Article
Language:English
Published: Kidlington Elsevier Inc 01.11.2011
Elsevier
Subjects:
2-phenylethanol
Bioconversions. Hemisynthesis
Biological and medical sciences
Biotechnology
Biotechnology - methods
Biotransformation
Ehrlich pathway
flavor
food industry
Fundamental and applied biological sciences. Psychology
In situ product removal
industrialization
Kluyveromyces - metabolism
l-phenylalanine
Methods. Procedures. Technologies
odors
perfumes
phenylalanine
Phenylalanine - metabolism
phenylethyl alcohol
Phenylethyl Alcohol - metabolism
Saccharomyces cerevisiae - metabolism
synthesis
2-phenylethanol
Ehrlich pathway
In situ product removal
l-phenylalanine
Biotransformation
Biotechnology
L-phenylalanine
Phenylalanine
In situ
Production
ISSN:0734-9750, 1873-1899, 1873-1899
Online Access:Get full text
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Summary:2-Phenylethanol (2-PE) is an important aromatic alcohol with a rose-like fragrance. It has been widely applied in the cosmetic, perfume, and food industries and is mainly produced by chemical synthesis. An alternative method for the production of natural flavors and fragrances is the microbial transformation process, which is attracting increasing attention because it is an environmentally friendly process and the products are considered “natural”. The production of 2-PE from L-phenylalanine by biotransformation is possible through the Ehrlich pathway and considerable progress has been made in the development of this process. The present report reviews recent advances in biotechnological production of 2-PE, with emphasis on the strategies used to increase production and the applications of in situ product removal techniques. Future research should focus on product scale-up and product recovery processes for the industrialization of microbial processes.
Bibliography:http://dx.doi.org/10.1016/j.biotechadv.2011.05.001
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ISSN:0734-9750
1873-1899
1873-1899
DOI:10.1016/j.biotechadv.2011.05.001