Endothelial dysfunction and vascular disease

The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth muscle, by releasing vasodilator substances. The best characterized endothelium-derived relaxing factor (EDRF) is nitric oxide (NO). The endothelial cells also evoke hyperpolarization of the cell membrane of vascul...

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Bibliographic Details
Published in:	Acta Physiologica Vol. 196; no. 2; pp. 193 - 222
Main Authors:	Vanhoutte, P.M, Shimokawa, H, Tang, E.H.C, Feletou, M
Format:	Journal Article
Language:	English
Published:	Oxford, UK Oxford, UK : Blackwell Publishing Ltd 01.06.2009 Blackwell Publishing Ltd Wiley-Blackwell
Subjects:	Animals Biological and medical sciences cyclooxygenase diabetes Endothelium, Vascular - metabolism Endothelium, Vascular - physiology Endothelium, Vascular - physiopathology Fundamental and applied biological sciences. Psychology G-proteins Humans hypertension Models, Biological nitric oxide prostaglandin synthase prostaglandins prostanoids Vascular Diseases - metabolism Vascular Diseases - physiopathology Vasoconstriction - physiology Vasodilation - physiology Vertebrates: anatomy and physiology, studies on body, several organs or systems Endocrinopathy Hypertension Prostaglandin-endoperoxide synthase Enzyme Diabetes mellitus Cardiovascular disease cyclooxygenase Vascular disease Vertebrata Mammalia prostanoids Nitric oxide Prostanoid Endothelial dysfunction Oxidoreductases G-proteins diabetes G protein
ISSN:	1748-1708, 1748-1716, 1748-1716
Online Access:	Get full text
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