La Crosse Encephalitis in Children

La Crosse virus is the most pathogenic member of the California encephalitis serogroup. It was first isolated from the brain of a four-year-old child who had died of “rural encephalitis” in La Crosse County, Wisconsin. 1 The virus is transmitted by the tree-hole mosquito, Aedes triseriatus, and caus...

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Bibliographic Details
Published in:The New England journal of medicine Vol. 344; no. 11; pp. 801 - 807
Main Authors: McJunkin, James E, de los Reyes, Emily C, Irazuzta, Jose E, Caceres, Manuel J, Khan, Raheel R, Minnich, Linda L, Fu, Kai D, Lovett, Gretchen D, Tsai, Theodore, Thompson, Ann
Format: Journal Article
Language:English
Published: Boston, MA Massachusetts Medical Society 15.03.2001
Subjects:
Adolescent
Analysis of Variance
Biological and medical sciences
Brain - diagnostic imaging
Brain - pathology
Child
Child, Preschool
Drug therapy
Electroencephalography
Encephalitis
Encephalitis, California - complications
Encephalitis, California - diagnosis
Encephalitis, California - physiopathology
Encephalitis, California - therapy
Female
Fever
Fever - etiology
Human viral diseases
Humans
Hyponatremia - etiology
Infant
Infectious diseases
La Crosse virus
Male
Medical sciences
Meningitis, Aseptic - etiology
Nervous System Diseases - etiology
Retrospective Studies
Risk Factors
Statistics, Nonparametric
Tomography, X-Ray Computed
Viral diseases
Viral diseases of the nervous system
Vomiting - etiology
La Crosse Wisconsin
West Virginia
United States > US
California encephalitis group virus
Bunyavirus
Insecta
Serology
La Crosse virus
Bunyaviridae
Arbovirus disease
Evolution
Diagnosis
Child
Human
Nervous system diseases
Antibody
Aedes triseriatus
Clinical form
Differential diagnostic
California encephalitis
Cerebral disorder
Infection
Virus
Symptomatology
Arthropoda
Viral disease
Culicidae
Central nervous system disease
Invertebrata
Diptera
ISSN:0028-4793, 1533-4406
Online Access:Get full text
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Summary:La Crosse virus is the most pathogenic member of the California encephalitis serogroup. It was first isolated from the brain of a four-year-old child who had died of “rural encephalitis” in La Crosse County, Wisconsin. 1 The virus is transmitted by the tree-hole mosquito, Aedes triseriatus, and causes the most prevalent arboviral infection in children in North America. 1 – 7 Nevertheless, La Crosse encephalitis often goes unrecognized. The virus typically cannot be recovered from cerebrospinal fluid, and the disease can masquerade as enteroviral meningitis when mild and as herpes simplex encephalitis when severe. 8 – 14 Currently, there is no antiviral therapy that has . . .
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ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM200103153441103