Metabolic Flexibility and Innate Immunity in Renal Ischemia Reperfusion Injury: The Fine Balance Between Adaptive Repair and Tissue Degeneration

Renal ischemia reperfusion injury (IRI), a common event after renal transplantation, causes acute kidney injury (AKI), increases the risk of delayed graft function (DGF), primes the donor kidney for rejection, and contributes to the long-term risk of graft loss. In the last decade, epidemiological s...

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Bibliographic Details
Published in:	Frontiers in Immunology Vol. 11; p. 1346
Main Authors:	Tammaro, Alessandra, Kers, Jesper, Scantlebery, Angelique M. L., Florquin, Sandrine
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media SA 07.07.2020 Frontiers Media S.A
Subjects:	Acute Kidney Injury Acute Kidney Injury - etiology Acute Kidney Injury - metabolism Acute Kidney Injury - pathology Animals Apoptosis cell death Cellular Senescence Computational Biology Computational Biology - methods Disease Progression Energy Metabolism Humans Immunity, Innate Immunologic diseases. Allergy Immunology innate immunity Kidney Transplantation Kidney Tubules Kidney Tubules - immunology Kidney Tubules - metabolism Kidney Tubules - pathology Ligands Mitochondria Mitochondria - genetics Mitochondria - immunology Mitochondria - metabolism RC581-607 Receptors, Pattern Recognition Receptors, Pattern Recognition - metabolism Reperfusion Injury Reperfusion Injury - etiology Reperfusion Injury - metabolism Reperfusion Injury - pathology senescence tubular repair Wound Healing senescence cell death innate immunity mitochondria kidney transplantation tubular repair
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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