Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing

Periodontitis has a polymicrobial etiology within the framework of a complex microbial ecosystem. With advances in sequencing technologies, comprehensive studies to elucidate bacterial community differences have recently become possible. We used 454 sequencing of 16S rRNA genes to compare subgingiva...

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Bibliographic Details
Published in:	The ISME Journal Vol. 6; no. 6; pp. 1176 - 1185
Main Authors:	Griffen, Ann L, Beall, Clifford J, Campbell, James H, Firestone, Noah D, Kumar, Purnima S, Yang, Zamin K, Podar, Mircea, Leys, Eugene J
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.06.2012 Oxford University Press Nature Publishing Group
Subjects:	Adult Bacilli Bacteria Bacteria - classification Bacteria - genetics Bacteria - growth & development Base Sequence Biomedical and Life Sciences Case-Control Studies Chronic Periodontitis - microbiology Community composition DNA, Bacterial - genetics Ecology Etiology Evolutionary Biology Female Firmicutes Genes, Bacterial Humans Life Sciences Male Microbial Ecology Microbial Genetics and Genomics Microbiology Middle Aged Mouth - microbiology Original original-article Periodontitis Phylogeny Proteobacteria RNA, Ribosomal, 16S - genetics rRNA 16S Sequence Analysis, DNA Spirochetes Taxa oral microbiome 16S rRNA pyrosequencing bacteria periodontitis
ISSN:	1751-7362, 1751-7370, 1751-7370
Online Access:	Get full text
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