Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

At the cellular level, development progresses through successive regulatory states, each characterized by their specific gene expression profile. However, the molecular mechanisms regulating first the priming and then maintenance of gene expression within one developmental pathway are essentially un...

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Veröffentlicht in:	Blood Jg. 114; H. 2; S. 299
Hauptverfasser:	Hoogenkamp, Maarten, Lichtinger, Monika, Krysinska, Hanna, Lancrin, Christophe, Clarke, Deborah, Williamson, Andrew, Mazzarella, Luca, Ingram, Richard, Jorgensen, Helle, Fisher, Amanda, Tenen, Daniel G, Kouskoff, Valerie, Lacaud, Georges, Bonifer, Constanze
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 09.07.2009
Schlagworte:	Animals Blood Cells - metabolism Cells, Cultured Chromatin - genetics Chromatin - metabolism Core Binding Factor Alpha 2 Subunit - deficiency Core Binding Factor Alpha 2 Subunit - genetics Core Binding Factor Alpha 2 Subunit - metabolism DNA Methylation Gene Expression Regulation Mice Promoter Regions, Genetic - genetics Protein Binding RNA, Messenger - genetics Time Factors
ISSN:	1528-0020, 1528-0020
Online-Zugang:	Weitere Angaben
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