Prevalence, incidence, predictive factors and prognosis of silent myocardial infarction: A review of the literature
The prevalence, incidence, risk factors and prognosis of silent myocardial infarction are less well known than those of silent myocardial ischaemia. The aims of this article are to evaluate the prevalence and incidence of silent myocardial infarction in subjects with or without a history of cardiova...
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| Published in: | Archives of cardiovascular diseases Vol. 104; no. 3; pp. 178 - 188 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Amsterdam
Elsevier Masson SAS
01.03.2011
Elsevier |
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| ISSN: | 1875-2136, 1875-2128, 1875-2128 |
| Online Access: | Get full text |
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| Abstract | The prevalence, incidence, risk factors and prognosis of silent myocardial infarction are less well known than those of silent myocardial ischaemia. The aims of this article are to evaluate the prevalence and incidence of silent myocardial infarction in subjects with or without a history of cardiovascular disease and in diabetic patients, and to identify potential risk factors and estimate prognosis through a review of the literature. A Medline search identified studies that provided data on the prevalence, incidence, potential risk factors and/or prognosis of silent myocardial infarction, among cohorts from the general population and large clinical studies of at-risk patients (with hypertension or a history of cardiovascular disease or diabetes). The search identified 15 studies in subjects from the general population, five in hypertensive patients, six in patients with a history of cardiovascular disease, and 10 in diabetic patients. The prevalence and incidence of silent myocardial infarction appear highly variable depending on the population studied, the patients’ ages, and the method used to detect silent myocardial infarction. In the general population, the prevalence of silent myocardial infarction increased markedly with increasing age (up to>5% in elderly subjects). Hypertension causes only a moderate increase in prevalence, whereas underlying cardiovascular diseases and diabetes are associated with marked increases in prevalence. The incidence of silent myocardial infarction changes in the same way. The main predictive factors of silent myocardial infarction are hypertension, history of cardiovascular diseases and diabetes duration. Silent myocardial infarction is associated with as poor a prognosis as clinical myocardial infarction. The frequency of silent myocardial infarction and the poor prognosis in at-risk patients amply justify its systematic early detection and active management.
Comparativement à l’ischémie myocardique silencieuse, la prévalence et l’incidence de l’infarctus du myocarde silencieux (IDMs), ses facteurs de risque et son pronostic sont mal connus. Évaluer la prévalence et l’incidence de l’IDMs chez des sujets avec/sans antécédents cardiovasculaires et chez des diabétiques, identifier ses facteurs de risque et estimer son pronostic, à partir des données de la littérature. La recherche a été effectuée dans Medline pour identifier, parmi les cohortes de sujets de population générale et les grandes études de patients à risque (hypertension, maladies cardio-vasculaires, diabète), celles évaluant la prévalence et l’incidence de l’IDMs, ses facteurs de risque et son pronostic. La recherche a identifié 15 études en population générale, cinq chez des patients hypertendus, six chez des patients avec antécédents cardiovasculaires et dix chez des patients diabétiques. La prévalence et l’incidence de l’IDMs apparaissent très variables selon la population étudiée, l’âge des patients et la méthode de détection. En population générale, la prévalence de l’IDMs augmente nettement avec l’âge (jusqu’à>5 % chez les sujets âgés). L’hypertension augmente modérément la prévalence, tandis que les maladies cardiovasculaires sous-jacentes et le diabète induisent une nette augmentation de la prévalence de l’IDMs. L’incidence de l’IDMs varie parallèlement. Les principaux facteurs pronostiques sont l’hypertension, les maladies cardiovasculaires et la durée du diabète. Enfin, le pronostic de l’IDMs est aussi péjoratif que celui de l’IDMs clinique. La fréquence et le mauvais pronostic de l’IDMs chez les patients à risque justifient son diagnostic systématique précoce et une prise en charge active. |
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| AbstractList | Summary The prevalence, incidence, risk factors and prognosis of silent myocardial infarction are less well known than those of silent myocardial ischaemia. The aims of this article are to evaluate the prevalence and incidence of silent myocardial infarction in subjects with or without a history of cardiovascular disease and in diabetic patients, and to identify potential risk factors and estimate prognosis through a review of the literature. A Medline search identified studies that provided data on the prevalence, incidence, potential risk factors and/or prognosis of silent myocardial infarction, among cohorts from the general population and large clinical studies of at-risk patients (with hypertension or a history of cardiovascular disease or diabetes). The search identified 15 studies in subjects from the general population, five in hypertensive patients, six in patients with a history of cardiovascular disease, and 10 in diabetic patients. The prevalence and incidence of silent myocardial infarction appear highly variable depending on the population studied, the patients’ ages, and the method used to detect silent myocardial infarction. In the general population, the prevalence of silent myocardial infarction increased markedly with increasing age (up to > 5% in elderly subjects). Hypertension causes only a moderate increase in prevalence, whereas underlying cardiovascular diseases and diabetes are associated with marked increases in prevalence. The incidence of silent myocardial infarction changes in the same way. The main predictive factors of silent myocardial infarction are hypertension, history of cardiovascular diseases and diabetes duration. Silent myocardial infarction is associated with as poor a prognosis as clinical myocardial infarction. The frequency of silent myocardial infarction and the poor prognosis in at-risk patients amply justify its systematic early detection and active management. The prevalence, incidence, risk factors and prognosis of silent myocardial infarction are less well known than those of silent myocardial ischaemia. The aims of this article are to evaluate the prevalence and incidence of silent myocardial infarction in subjects with or without a history of cardiovascular disease and in diabetic patients, and to identify potential risk factors and estimate prognosis through a review of the literature. A Medline search identified studies that provided data on the prevalence, incidence, potential risk factors and/or prognosis of silent myocardial infarction, among cohorts from the general population and large clinical studies of at-risk patients (with hypertension or a history of cardiovascular disease or diabetes). The search identified 15 studies in subjects from the general population, five in hypertensive patients, six in patients with a history of cardiovascular disease, and 10 in diabetic patients. The prevalence and incidence of silent myocardial infarction appear highly variable depending on the population studied, the patients' ages, and the method used to detect silent myocardial infarction. In the general population, the prevalence of silent myocardial infarction increased markedly with increasing age (up to>5% in elderly subjects). Hypertension causes only a moderate increase in prevalence, whereas underlying cardiovascular diseases and diabetes are associated with marked increases in prevalence. The incidence of silent myocardial infarction changes in the same way. The main predictive factors of silent myocardial infarction are hypertension, history of cardiovascular diseases and diabetes duration. Silent myocardial infarction is associated with as poor a prognosis as clinical myocardial infarction. The frequency of silent myocardial infarction and the poor prognosis in at-risk patients amply justify its systematic early detection and active management.The prevalence, incidence, risk factors and prognosis of silent myocardial infarction are less well known than those of silent myocardial ischaemia. The aims of this article are to evaluate the prevalence and incidence of silent myocardial infarction in subjects with or without a history of cardiovascular disease and in diabetic patients, and to identify potential risk factors and estimate prognosis through a review of the literature. A Medline search identified studies that provided data on the prevalence, incidence, potential risk factors and/or prognosis of silent myocardial infarction, among cohorts from the general population and large clinical studies of at-risk patients (with hypertension or a history of cardiovascular disease or diabetes). The search identified 15 studies in subjects from the general population, five in hypertensive patients, six in patients with a history of cardiovascular disease, and 10 in diabetic patients. The prevalence and incidence of silent myocardial infarction appear highly variable depending on the population studied, the patients' ages, and the method used to detect silent myocardial infarction. In the general population, the prevalence of silent myocardial infarction increased markedly with increasing age (up to>5% in elderly subjects). Hypertension causes only a moderate increase in prevalence, whereas underlying cardiovascular diseases and diabetes are associated with marked increases in prevalence. The incidence of silent myocardial infarction changes in the same way. The main predictive factors of silent myocardial infarction are hypertension, history of cardiovascular diseases and diabetes duration. Silent myocardial infarction is associated with as poor a prognosis as clinical myocardial infarction. The frequency of silent myocardial infarction and the poor prognosis in at-risk patients amply justify its systematic early detection and active management. The prevalence, incidence, risk factors and prognosis of silent myocardial infarction are less well known than those of silent myocardial ischaemia. The aims of this article are to evaluate the prevalence and incidence of silent myocardial infarction in subjects with or without a history of cardiovascular disease and in diabetic patients, and to identify potential risk factors and estimate prognosis through a review of the literature. A Medline search identified studies that provided data on the prevalence, incidence, potential risk factors and/or prognosis of silent myocardial infarction, among cohorts from the general population and large clinical studies of at-risk patients (with hypertension or a history of cardiovascular disease or diabetes). The search identified 15 studies in subjects from the general population, five in hypertensive patients, six in patients with a history of cardiovascular disease, and 10 in diabetic patients. The prevalence and incidence of silent myocardial infarction appear highly variable depending on the population studied, the patients' ages, and the method used to detect silent myocardial infarction. In the general population, the prevalence of silent myocardial infarction increased markedly with increasing age (up to>5% in elderly subjects). Hypertension causes only a moderate increase in prevalence, whereas underlying cardiovascular diseases and diabetes are associated with marked increases in prevalence. The incidence of silent myocardial infarction changes in the same way. The main predictive factors of silent myocardial infarction are hypertension, history of cardiovascular diseases and diabetes duration. Silent myocardial infarction is associated with as poor a prognosis as clinical myocardial infarction. The frequency of silent myocardial infarction and the poor prognosis in at-risk patients amply justify its systematic early detection and active management. The prevalence, incidence, risk factors and prognosis of silent myocardial infarction are less well known than those of silent myocardial ischaemia. The aims of this article are to evaluate the prevalence and incidence of silent myocardial infarction in subjects with or without a history of cardiovascular disease and in diabetic patients, and to identify potential risk factors and estimate prognosis through a review of the literature. A Medline search identified studies that provided data on the prevalence, incidence, potential risk factors and/or prognosis of silent myocardial infarction, among cohorts from the general population and large clinical studies of at-risk patients (with hypertension or a history of cardiovascular disease or diabetes). The search identified 15 studies in subjects from the general population, five in hypertensive patients, six in patients with a history of cardiovascular disease, and 10 in diabetic patients. The prevalence and incidence of silent myocardial infarction appear highly variable depending on the population studied, the patients’ ages, and the method used to detect silent myocardial infarction. In the general population, the prevalence of silent myocardial infarction increased markedly with increasing age (up to>5% in elderly subjects). Hypertension causes only a moderate increase in prevalence, whereas underlying cardiovascular diseases and diabetes are associated with marked increases in prevalence. The incidence of silent myocardial infarction changes in the same way. The main predictive factors of silent myocardial infarction are hypertension, history of cardiovascular diseases and diabetes duration. Silent myocardial infarction is associated with as poor a prognosis as clinical myocardial infarction. The frequency of silent myocardial infarction and the poor prognosis in at-risk patients amply justify its systematic early detection and active management. Comparativement à l’ischémie myocardique silencieuse, la prévalence et l’incidence de l’infarctus du myocarde silencieux (IDMs), ses facteurs de risque et son pronostic sont mal connus. Évaluer la prévalence et l’incidence de l’IDMs chez des sujets avec/sans antécédents cardiovasculaires et chez des diabétiques, identifier ses facteurs de risque et estimer son pronostic, à partir des données de la littérature. La recherche a été effectuée dans Medline pour identifier, parmi les cohortes de sujets de population générale et les grandes études de patients à risque (hypertension, maladies cardio-vasculaires, diabète), celles évaluant la prévalence et l’incidence de l’IDMs, ses facteurs de risque et son pronostic. La recherche a identifié 15 études en population générale, cinq chez des patients hypertendus, six chez des patients avec antécédents cardiovasculaires et dix chez des patients diabétiques. La prévalence et l’incidence de l’IDMs apparaissent très variables selon la population étudiée, l’âge des patients et la méthode de détection. En population générale, la prévalence de l’IDMs augmente nettement avec l’âge (jusqu’à>5 % chez les sujets âgés). L’hypertension augmente modérément la prévalence, tandis que les maladies cardiovasculaires sous-jacentes et le diabète induisent une nette augmentation de la prévalence de l’IDMs. L’incidence de l’IDMs varie parallèlement. Les principaux facteurs pronostiques sont l’hypertension, les maladies cardiovasculaires et la durée du diabète. Enfin, le pronostic de l’IDMs est aussi péjoratif que celui de l’IDMs clinique. La fréquence et le mauvais pronostic de l’IDMs chez les patients à risque justifient son diagnostic systématique précoce et une prise en charge active. |
| Author | Valensi, Paul Cottin, Yves Lorgis, Luc |
| Author_xml | – sequence: 1 givenname: Paul surname: Valensi fullname: Valensi, Paul email: paul.valensi@jvr.aphp.fr organization: Department of Endocrinology–Diabetology–Nutrition, Paris-Nord University, Jean-Verdier Hospital, AP–HP, CNRH-IdF, avenue du 14-Juillet, 93143 Bondy cedex, France – sequence: 2 givenname: Luc surname: Lorgis fullname: Lorgis, Luc organization: Department of Cardiology, University Hospital, 21000 Dijon, France – sequence: 3 givenname: Yves surname: Cottin fullname: Cottin, Yves organization: Department of Cardiology, University Hospital, 21000 Dijon, France |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24073341$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/21497307$$D View this record in MEDLINE/PubMed |
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| Copyright | 2011 Elsevier Masson SAS Elsevier Masson SAS 2015 INIST-CNRS Copyright © 2011 Elsevier Masson SAS. All rights reserved. |
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| Keywords | Myocardial infarction Hypertension Prévalence Prevalence Diabetes mellitus Maladie cardiovasculaire Infarctus du myocarde Diabète Cardiovascular diseases Incidence Endocrinopathy Prognosis Cardiovascular disease Asymptomatic Review Coronary heart disease Epidemiology Myocardial disease Cardiology Predictive factor Bibliographic review |
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| SubjectTerms | Adult Age Factors Aged Aged, 80 and over Arterial hypertension. Arterial hypotension Asymptomatic Diseases Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cardiovascular Cardiovascular diseases Coronary heart disease Diabetes mellitus Diabetes Mellitus - epidemiology Diabetes. Impaired glucose tolerance Diabète Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Heart Humans Hypertension Hypertension - epidemiology Incidence Infarctus du myocarde Internal Medicine Maladie cardiovasculaire Male Medical sciences Middle Aged Myocardial infarction Myocardial Infarction - diagnosis Myocardial Infarction - epidemiology Myocardial Infarction - therapy Prevalence Prognosis Prévalence Risk Assessment Risk Factors |
| Title | Prevalence, incidence, predictive factors and prognosis of silent myocardial infarction: A review of the literature |
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