PV Interneurons: Critical Regulators of E/I Balance for Prefrontal Cortex-Dependent Behavior and Psychiatric Disorders

Elucidating the prefrontal cortical microcircuit has been challenging, given its role in multiple complex behaviors, including working memory, cognitive flexibility, attention, social interaction and emotional regulation. Additionally, previous methodological limitations made it difficult to parse o...

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Bibliographic Details
Published in:	Frontiers in neural circuits Vol. 12; p. 37
Main Authors:	Ferguson, Brielle R., Gao, Wen-Jun
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Research Foundation 16.05.2018 Frontiers Media S.A
Subjects:	Autism Behavior Brain research cognition Cognitive ability Complications excitation/inhibition balance Flexibility GABA Information processing Interneurons Memory Mental disorders Neurons Neuroscience Neurosciences Parvalbumin Prefrontal cortex psychiatric disorders PV interneurons Schizophrenia Short term memory Therapeutic applications γ-Aminobutyric acid United States > US GABA PV interneurons excitation/inhibition balance cognition prefrontal cortex psychiatric disorders
ISSN:	1662-5110, 1662-5110
Online Access:	Get full text
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