Improving the Breadth of the Host’s Immune Response to Lassa Virus

In 2017, the global Coalition for Epidemic Preparedness (CEPI) declared Lassa virus disease to be one of the world’s foremost biothreats. In January 2018, World Health Organization experts met to address the Lassa biothreat. It was commonly recognized that the diversity of Lassa virus (LASV) isolate...

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Veröffentlicht in:	Pathogens (Basel) Jg. 7; H. 4; S. 84
Hauptverfasser:	Zapata, Juan, Medina-Moreno, Sandra, Guzmán-Cardozo, Camila, Salvato, Maria
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 28.10.2018 MDPI
Schlagworte:	Antigens B cell anergy broadly-neutralizing antibodies Chemokines conformational antigens conserved antigens cross-restriction Cytokines Dendritic cells Disease dominant and subdominant epitopes Ebola virus Edema Epidemics Fc-gamma receptors focused immunity Genetic diversity Hearing loss Immune response Immune system Infections Influenza Interferon Lassa virus disease (LVD) Medical research mimicry Pathogenesis Pathogens Public health Review vaccine breadth Vaccines Viral diseases Viruses West Africa focused immunity Lassa virus disease (LVD) conserved antigens broadly-neutralizing antibodies vaccine breadth mimicry dominant and subdominant epitopes conformational antigens cross-restriction B cell anergy Fc-gamma receptors
ISSN:	2076-0817, 2076-0817
Online-Zugang:	Volltext
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