Epidemiology, Risk Factors, and Clinical Features of Intracerebral Hemorrhage: An Update

Intracerebral hemorrhage (ICH) is the second most common subtype of stroke and a critical disease usually leading to severe disability or death. ICH is more common in Asians, advanced age, male sex, and low- and middle-income countries. The case fatality rate of ICH is high (40% at 1 month and 54% a...

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Vydáno v:Journal of stroke Ročník 19; číslo 1; s. 3 - 10
Hlavní autoři: An, Sang Joon, Kim, Tae Jung, Yoon, Byung-Woo
Médium: Journal Article
Jazyk:angličtina
Vydáno: Korea (South) Korean Stroke Society 01.01.2017
대한뇌졸중학회
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ISSN:2287-6391, 1229-4101, 2287-6405
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Shrnutí:Intracerebral hemorrhage (ICH) is the second most common subtype of stroke and a critical disease usually leading to severe disability or death. ICH is more common in Asians, advanced age, male sex, and low- and middle-income countries. The case fatality rate of ICH is high (40% at 1 month and 54% at 1 year), and only 12% to 39% of survivors can achieve long-term functional independence. Risk factors of ICH are hypertension, current smoking, excessive alcohol consumption, hypocholesterolemia, and drugs. Old age, male sex, Asian ethnicity, chronic kidney disease, cerebral amyloid angiopathy (CAA), and cerebral microbleeds (CMBs) increase the risk of ICH. Clinical presentation varies according to the size and location of hematoma, and intraventricular extension of hemorrhage. Patients with CAA-related ICH frequently have concomitant cognitive impairment. Anticoagulation related ICH is increasing recently as the elderly population who have atrial fibrillation is increasing. As non-vitamin K antagonist oral anticoagulants (NOACs) are currently replacing warfarin, management of NOAC-associated ICH has become an emerging issue.
Bibliografie:ObjectType-Article-2
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G704-SER000008649.2017.19.1.017
ISSN:2287-6391
1229-4101
2287-6405
DOI:10.5853/jos.2016.00864