Long-Term Risk of Infective Endocarditis After Transcatheter Aortic Valve Replacement
Patients undergoing surgical aortic valve replacement (SAVR) are considered at high risk of infective endocarditis (IE). However, data on the risk of IE following transcatheter aortic valve replacement (TAVR) are sparse and limited by the lack of long-term follow-up as well as a direct comparison wi...
Uloženo v:
| Vydáno v: | Journal of the American College of Cardiology Ročník 73; číslo 13; s. 1646 |
|---|---|
| Hlavní autoři: | , , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
United States
09.04.2019
|
| Témata: | |
| ISSN: | 1558-3597, 1558-3597 |
| On-line přístup: | Zjistit podrobnosti o přístupu |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
| Abstract | Patients undergoing surgical aortic valve replacement (SAVR) are considered at high risk of infective endocarditis (IE). However, data on the risk of IE following transcatheter aortic valve replacement (TAVR) are sparse and limited by the lack of long-term follow-up as well as a direct comparison with patients undergoing SAVR.
This study sought to investigate the long-term incidence of IE in patients undergoing TAVR and to compare the long-term risk of IE with patients undergoing isolated SAVR.
In this nationwide observational cohort study, all patients undergoing TAVR and isolated SAVR from January 1, 2008, to December 31, 2016, with no history of IE and alive at discharge were identified using data from Danish nationwide registries.
A total of 2,632 patients undergoing TAVR and 3,777 patients undergoing isolated SAVR were identified. During a mean follow-up of 3.6 years, 115 patients (4.4%) with TAVR and 186 patients (4.9%) with SAVR were admitted with IE. The median time from procedure to IE hospitalization was 352 days (25th to 75th percentile: 133 to 778 days) in the TAVR group and 625 days (25th to 75th percentile: 209 to 1,385 days) in the SAVR group. The crude incidence rates of IE were 1.6 (95% confidence interval [CI]: 1.4 to 1.9) and 1.2 (95% CI: 1.0 to 1.4) events per 100 person-years in TAVR and SAVR patients, respectively. The cumulative 1-year risk of IE was 2.3% (95% CI: 1.8% to 2.9%) and 1.8% (95% CI: 1.4% to 2.3%) in TAVR and SAVR patients, respectively. Correspondingly, the cumulative 5-year risk of IE was 5.8% (95% CI: 4.7% to 7.0%) and 5.1% (95% CI: 4.4% to 6.0%), respectively. In multivariable Cox proportional hazard analysis, TAVR was not associated with a statistically significant different risk of IE compared with SAVR (hazard ratio: 1.12; 95% CI: 0.84 to 1.49).
The 5-year incidence of IE following TAVR was 5.8% and not significantly different than the incidence following SAVR. |
|---|---|
| AbstractList | Patients undergoing surgical aortic valve replacement (SAVR) are considered at high risk of infective endocarditis (IE). However, data on the risk of IE following transcatheter aortic valve replacement (TAVR) are sparse and limited by the lack of long-term follow-up as well as a direct comparison with patients undergoing SAVR.
This study sought to investigate the long-term incidence of IE in patients undergoing TAVR and to compare the long-term risk of IE with patients undergoing isolated SAVR.
In this nationwide observational cohort study, all patients undergoing TAVR and isolated SAVR from January 1, 2008, to December 31, 2016, with no history of IE and alive at discharge were identified using data from Danish nationwide registries.
A total of 2,632 patients undergoing TAVR and 3,777 patients undergoing isolated SAVR were identified. During a mean follow-up of 3.6 years, 115 patients (4.4%) with TAVR and 186 patients (4.9%) with SAVR were admitted with IE. The median time from procedure to IE hospitalization was 352 days (25th to 75th percentile: 133 to 778 days) in the TAVR group and 625 days (25th to 75th percentile: 209 to 1,385 days) in the SAVR group. The crude incidence rates of IE were 1.6 (95% confidence interval [CI]: 1.4 to 1.9) and 1.2 (95% CI: 1.0 to 1.4) events per 100 person-years in TAVR and SAVR patients, respectively. The cumulative 1-year risk of IE was 2.3% (95% CI: 1.8% to 2.9%) and 1.8% (95% CI: 1.4% to 2.3%) in TAVR and SAVR patients, respectively. Correspondingly, the cumulative 5-year risk of IE was 5.8% (95% CI: 4.7% to 7.0%) and 5.1% (95% CI: 4.4% to 6.0%), respectively. In multivariable Cox proportional hazard analysis, TAVR was not associated with a statistically significant different risk of IE compared with SAVR (hazard ratio: 1.12; 95% CI: 0.84 to 1.49).
The 5-year incidence of IE following TAVR was 5.8% and not significantly different than the incidence following SAVR. Patients undergoing surgical aortic valve replacement (SAVR) are considered at high risk of infective endocarditis (IE). However, data on the risk of IE following transcatheter aortic valve replacement (TAVR) are sparse and limited by the lack of long-term follow-up as well as a direct comparison with patients undergoing SAVR.BACKGROUNDPatients undergoing surgical aortic valve replacement (SAVR) are considered at high risk of infective endocarditis (IE). However, data on the risk of IE following transcatheter aortic valve replacement (TAVR) are sparse and limited by the lack of long-term follow-up as well as a direct comparison with patients undergoing SAVR.This study sought to investigate the long-term incidence of IE in patients undergoing TAVR and to compare the long-term risk of IE with patients undergoing isolated SAVR.OBJECTIVESThis study sought to investigate the long-term incidence of IE in patients undergoing TAVR and to compare the long-term risk of IE with patients undergoing isolated SAVR.In this nationwide observational cohort study, all patients undergoing TAVR and isolated SAVR from January 1, 2008, to December 31, 2016, with no history of IE and alive at discharge were identified using data from Danish nationwide registries.METHODSIn this nationwide observational cohort study, all patients undergoing TAVR and isolated SAVR from January 1, 2008, to December 31, 2016, with no history of IE and alive at discharge were identified using data from Danish nationwide registries.A total of 2,632 patients undergoing TAVR and 3,777 patients undergoing isolated SAVR were identified. During a mean follow-up of 3.6 years, 115 patients (4.4%) with TAVR and 186 patients (4.9%) with SAVR were admitted with IE. The median time from procedure to IE hospitalization was 352 days (25th to 75th percentile: 133 to 778 days) in the TAVR group and 625 days (25th to 75th percentile: 209 to 1,385 days) in the SAVR group. The crude incidence rates of IE were 1.6 (95% confidence interval [CI]: 1.4 to 1.9) and 1.2 (95% CI: 1.0 to 1.4) events per 100 person-years in TAVR and SAVR patients, respectively. The cumulative 1-year risk of IE was 2.3% (95% CI: 1.8% to 2.9%) and 1.8% (95% CI: 1.4% to 2.3%) in TAVR and SAVR patients, respectively. Correspondingly, the cumulative 5-year risk of IE was 5.8% (95% CI: 4.7% to 7.0%) and 5.1% (95% CI: 4.4% to 6.0%), respectively. In multivariable Cox proportional hazard analysis, TAVR was not associated with a statistically significant different risk of IE compared with SAVR (hazard ratio: 1.12; 95% CI: 0.84 to 1.49).RESULTSA total of 2,632 patients undergoing TAVR and 3,777 patients undergoing isolated SAVR were identified. During a mean follow-up of 3.6 years, 115 patients (4.4%) with TAVR and 186 patients (4.9%) with SAVR were admitted with IE. The median time from procedure to IE hospitalization was 352 days (25th to 75th percentile: 133 to 778 days) in the TAVR group and 625 days (25th to 75th percentile: 209 to 1,385 days) in the SAVR group. The crude incidence rates of IE were 1.6 (95% confidence interval [CI]: 1.4 to 1.9) and 1.2 (95% CI: 1.0 to 1.4) events per 100 person-years in TAVR and SAVR patients, respectively. The cumulative 1-year risk of IE was 2.3% (95% CI: 1.8% to 2.9%) and 1.8% (95% CI: 1.4% to 2.3%) in TAVR and SAVR patients, respectively. Correspondingly, the cumulative 5-year risk of IE was 5.8% (95% CI: 4.7% to 7.0%) and 5.1% (95% CI: 4.4% to 6.0%), respectively. In multivariable Cox proportional hazard analysis, TAVR was not associated with a statistically significant different risk of IE compared with SAVR (hazard ratio: 1.12; 95% CI: 0.84 to 1.49).The 5-year incidence of IE following TAVR was 5.8% and not significantly different than the incidence following SAVR.CONCLUSIONSThe 5-year incidence of IE following TAVR was 5.8% and not significantly different than the incidence following SAVR. |
| Author | Butt, Jawad H Ihlemann, Nikolaj Gislason, Gunnar H De Backer, Ole Havers-Borgersen, Eva Fosbøl, Emil L Søndergaard, Lars Køber, Lars Torp-Pedersen, Christian |
| Author_xml | – sequence: 1 givenname: Jawad H surname: Butt fullname: Butt, Jawad H email: jawad_butt91@hotmail.com organization: Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. Electronic address: jawad_butt91@hotmail.com – sequence: 2 givenname: Nikolaj surname: Ihlemann fullname: Ihlemann, Nikolaj organization: Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark – sequence: 3 givenname: Ole surname: De Backer fullname: De Backer, Ole organization: Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark – sequence: 4 givenname: Lars surname: Søndergaard fullname: Søndergaard, Lars organization: Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark – sequence: 5 givenname: Eva surname: Havers-Borgersen fullname: Havers-Borgersen, Eva organization: Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark – sequence: 6 givenname: Gunnar H surname: Gislason fullname: Gislason, Gunnar H organization: Department of Cardiovascular Epidemiology and Research, The Danish Heart Foundation, Copenhagen, Denmark; Department of Cardiology, Herlev and Gentofte University Hospital, Hellerup, Denmark; National Institute of Public Health, University of Southern Denmark, Odense, Denmark – sequence: 7 givenname: Christian surname: Torp-Pedersen fullname: Torp-Pedersen, Christian organization: Department of Health Science and Technology, Aalborg University, Aalborg, Denmark – sequence: 8 givenname: Lars surname: Køber fullname: Køber, Lars organization: Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark – sequence: 9 givenname: Emil L surname: Fosbøl fullname: Fosbøl, Emil L organization: Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/30947917$$D View this record in MEDLINE/PubMed |
| BookMark | eNpNkN1KwzAcxYNM3Ie-gBfSS29ak7RJmssxpg4GwpjiXUmTf7WzTWeSDXybPcuezIoTvDrnwO-cizNGA9tZQOia4IRgwu82yUZpnVBM8oTQBIv8DI0IY3mcMikG__wQjb3fYIx5TuQFGqZYZkISMUKvy86-xWtwbbSq_UfUVdHCVqBDvYdobk2nlTN1qP3xMK0CuGjtlPVahXf4SdPOhVofDy-q2cPxsIJtozS0YMMlOq9U4-HqpBP0fD9fzx7j5dPDYjZdxpoxHmKlKo0FVVQyoCQFXVKoDKSGU51xmepcMaWFMCXONJfcgOGM96msaN81dIJuf3e3rvvcgQ9FW3sNTaMsdDtfUIr7nYylokdvTuiubMEUW1e3yn0Vf2_Qb_bnaKs |
| CitedBy_id | crossref_primary_10_1080_00015385_2021_1894726 crossref_primary_10_1016_S0140_6736_24_01098_5 crossref_primary_10_3390_jcm13154532 crossref_primary_10_3390_pathogens13121039 crossref_primary_10_1016_j_cjca_2021_10_004 crossref_primary_10_1053_j_jvca_2022_12_030 crossref_primary_10_1080_24748706_2020_1733718 crossref_primary_10_1111_jocs_16486 crossref_primary_10_1016_j_amjcard_2022_02_034 crossref_primary_10_1093_eurheartj_ehaf219 crossref_primary_10_1002_ccd_30694 crossref_primary_10_3390_antibiotics10010050 crossref_primary_10_1016_j_jacc_2020_04_057 crossref_primary_10_1093_eurheartj_ehab375 crossref_primary_10_1016_j_lpm_2019_04_009 crossref_primary_10_1186_s42825_022_00105_3 crossref_primary_10_3389_fcvm_2019_00145 crossref_primary_10_2478_rjc_2024_0020 crossref_primary_10_7759_cureus_49048 crossref_primary_10_1016_j_ijid_2025_108011 crossref_primary_10_1016_j_amjcard_2021_04_007 crossref_primary_10_3390_antibiotics10121446 crossref_primary_10_1007_s00392_023_02356_4 crossref_primary_10_3390_prosthesis6060110 crossref_primary_10_1007_s15010_024_02302_0 crossref_primary_10_1016_j_eimce_2019_11_003 crossref_primary_10_3389_fcell_2022_995508 crossref_primary_10_1016_j_jtcvs_2021_12_027 crossref_primary_10_1093_eurheartj_ehz734 crossref_primary_10_1093_cid_ciab1004 crossref_primary_10_1016_j_jtcvs_2021_04_086 crossref_primary_10_1053_j_jvca_2019_10_011 crossref_primary_10_1161_JAHA_120_017347 crossref_primary_10_1016_j_ihj_2024_01_007 crossref_primary_10_1016_j_cmi_2020_01_028 crossref_primary_10_7759_cureus_70268 crossref_primary_10_1093_eurheartj_ehad193 crossref_primary_10_1016_j_cmi_2020_01_036 crossref_primary_10_1016_j_eimce_2019_12_002 crossref_primary_10_1016_j_acvd_2024_12_007 crossref_primary_10_3390_life13101980 crossref_primary_10_1016_j_ancard_2020_07_013 crossref_primary_10_1007_s12471_020_01420_2 crossref_primary_10_1053_j_jvca_2023_04_030 crossref_primary_10_1016_j_jacc_2018_12_077 crossref_primary_10_2459_JCM_0000000000001001 crossref_primary_10_1007_s12350_020_02035_1 crossref_primary_10_2459_JCM_0000000000000961 crossref_primary_10_7759_cureus_29254 crossref_primary_10_1155_2021_5569533 crossref_primary_10_1053_j_ro_2022_07_002 crossref_primary_10_1161_CIRCULATIONAHA_119_041399 crossref_primary_10_1016_j_jacadv_2024_101571 crossref_primary_10_1093_eurheartj_ehz588 crossref_primary_10_1038_s41569_019_0215_0 crossref_primary_10_1007_s00380_022_02119_7 crossref_primary_10_1016_j_jcin_2020_05_012 crossref_primary_10_1007_s40520_019_01401_5 crossref_primary_10_1186_s12872_021_02364_0 crossref_primary_10_3390_jcm9092694 crossref_primary_10_1016_j_circv_2025_07_001 crossref_primary_10_1007_s12471_020_01494_y crossref_primary_10_1016_j_jacc_2022_11_028 crossref_primary_10_1007_s12928_020_00675_1 crossref_primary_10_1016_j_mmifmc_2023_01_007 crossref_primary_10_3390_ph15010014 crossref_primary_10_1007_s11845_022_02991_2 crossref_primary_10_1093_ejcts_ezac075 crossref_primary_10_3390_diagnostics13111908 crossref_primary_10_1007_s00392_022_01998_0 crossref_primary_10_1080_14779072_2020_1839419 crossref_primary_10_3390_diagnostics14121259 crossref_primary_10_1007_s11886_024_02076_9 crossref_primary_10_1111_jce_16099 crossref_primary_10_1016_j_ancard_2020_09_036 crossref_primary_10_3390_pathogens12020255 crossref_primary_10_1016_j_jacc_2020_04_044 crossref_primary_10_7759_cureus_59398 crossref_primary_10_1016_j_jtcvs_2019_07_149 crossref_primary_10_1161_JAHA_120_020368 crossref_primary_10_1016_j_jacc_2021_11_056 crossref_primary_10_1007_s11886_024_02137_z crossref_primary_10_1053_j_optechstcvs_2021_09_005 crossref_primary_10_1007_s12350_019_01963_x crossref_primary_10_1016_j_cjca_2025_09_012 crossref_primary_10_3390_jcm14113866 |
| ContentType | Journal Article |
| Copyright | Copyright © 2019 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. |
| Copyright_xml | – notice: Copyright © 2019 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. |
| DBID | CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1016/j.jacc.2018.12.078 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | no_fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1558-3597 |
| ExternalDocumentID | 30947917 |
| Genre | Journal Article Observational Study |
| GeographicLocations | Denmark |
| GeographicLocations_xml | – name: Denmark |
| GroupedDBID | --- --K --M .1- .FO .~1 0R~ 18M 1B1 1P~ 1~. 1~5 2WC 4.4 457 4G. 53G 5GY 5RE 5VS 6PF 7-5 71M 8P~ AABNK AABVL AACTN AAEDT AAEDW AAIKJ AAKUH AALRI AAOAW AAQFI AAQQT AAXUO ABBQC ABFNM ABFRF ABLJU ABMAC ABMZM ABOCM ACGFO ACGFS ACIUM ACJTP ACPRK ADBBV ADEZE ADVLN AEFWE AEKER AENEX AEVXI AEXQZ AFCTW AFETI AFRAH AFRHN AFTJW AGYEJ AHMBA AITUG AJRQY AKRWK ALMA_UNASSIGNED_HOLDINGS AMRAJ BAWUL BLXMC CGR CS3 CUY CVF DIK DU5 E3Z EBS ECM EIF EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FNPLU G-Q GBLVA GX1 HVGLF IHE IXB J1W K-O KQ8 L7B MO0 N9A NPM O-L O9- OA. OAUVE OK1 OL~ OZT P-8 P-9 P2P PC. PQQKQ Q38 RIG ROL RPZ SCC SDF SDG SDP SES SSZ TR2 UNMZH UV1 W8F WH7 WOQ WOW YYM YZZ Z5R 7X8 ACVFH ADCNI AEUPX AFPUW AIGII AKBMS AKYEP EFKBS EFLBG ~HD |
| ID | FETCH-LOGICAL-c556t-aafc072a295e213ecb2efde3d62c4693c8a5ac77db04c696ded656db0bf2aafd2 |
| IEDL.DBID | 7X8 |
| ISICitedReferencesCount | 98 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000462853800007&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1558-3597 |
| IngestDate | Sun Sep 28 01:39:13 EDT 2025 Thu Apr 03 07:05:33 EDT 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 13 |
| Keywords | aortic valve replacement epidemiology infective endocarditis |
| Language | English |
| License | Copyright © 2019 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c556t-aafc072a295e213ecb2efde3d62c4693c8a5ac77db04c696ded656db0bf2aafd2 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Undefined-3 |
| OpenAccessLink | https://www.clinicalkey.com/#!/content/1-s2.0-S0735109719304814 |
| PMID | 30947917 |
| PQID | 2204694537 |
| PQPubID | 23479 |
| ParticipantIDs | proquest_miscellaneous_2204694537 pubmed_primary_30947917 |
| PublicationCentury | 2000 |
| PublicationDate | 2019-04-09 |
| PublicationDateYYYYMMDD | 2019-04-09 |
| PublicationDate_xml | – month: 04 year: 2019 text: 2019-04-09 day: 09 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Journal of the American College of Cardiology |
| PublicationTitleAlternate | J Am Coll Cardiol |
| PublicationYear | 2019 |
| References | 30947918 - J Am Coll Cardiol. 2019 Apr 9;73(13):1656-1658 |
| References_xml | – reference: 30947918 - J Am Coll Cardiol. 2019 Apr 9;73(13):1656-1658 |
| SSID | ssj0006819 |
| Score | 2.5838075 |
| Snippet | Patients undergoing surgical aortic valve replacement (SAVR) are considered at high risk of infective endocarditis (IE). However, data on the risk of IE... |
| SourceID | proquest pubmed |
| SourceType | Aggregation Database Index Database |
| StartPage | 1646 |
| SubjectTerms | Aged Aged, 80 and over Denmark - epidemiology Endocarditis - epidemiology Endocarditis - etiology Female Follow-Up Studies Humans Incidence Male Transcatheter Aortic Valve Replacement - adverse effects Transcatheter Aortic Valve Replacement - mortality |
| Title | Long-Term Risk of Infective Endocarditis After Transcatheter Aortic Valve Replacement |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/30947917 https://www.proquest.com/docview/2204694537 |
| Volume | 73 |
| WOSCitedRecordID | wos000462853800007&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1bS8MwFA7qRHzxfpk3IvgabJOmaZ9kyIaCG0M22VtJc5GptNPO_X5P0o49CYIvhUDTy-npyXcuOR9CN-BvBUkea8LThJMIrDDJBWMk9fsWjeWptZ5sQgwGyWSSDpuAW9WUVS5tojfUulQuRn5LqfPkIs7E3eyTONYol11tKDTWUYsBlHElXWKy6hYeJ57YA5bMhDBAzs2mmbq-600q18IwTHw4UCS_Q0y_1PR2__uQe2inAZm4U2vFPlozxQHa6jdp9EM0fiqLVzICo4yfp9U7Li1-rIuyFgZ3C7iP05v5tMIdRyGO_YLmG7y6Uad018Uv8gPOBgDvAvEuxniExr3u6P6BNPwKRHEez4mUVgWCSppyQ0NmVE6N1YbpmCp4DaYSyaUSQudBpOI01kYD-oNRbinM1fQYbRRlYU4R1lJxAIvMxNpGMjWSSWHDMI-M60dHZRtdLwWWgf66pIQsTPldZSuRtdFJLfVsVjfayBj4ngL8ybM_zD5H2_AxfaInSC9Qy8Lfay7RplqAtL6uvGLAcTDs_wDE1cQG |
| linkProvider | ProQuest |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Long-Term+Risk+of+Infective+Endocarditis+After+Transcatheter+Aortic+Valve+Replacement&rft.jtitle=Journal+of+the+American+College+of+Cardiology&rft.au=Butt%2C+Jawad+H&rft.au=Ihlemann%2C+Nikolaj&rft.au=De+Backer%2C+Ole&rft.au=S%C3%B8ndergaard%2C+Lars&rft.date=2019-04-09&rft.issn=1558-3597&rft.eissn=1558-3597&rft.volume=73&rft.issue=13&rft.spage=1646&rft_id=info:doi/10.1016%2Fj.jacc.2018.12.078&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1558-3597&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1558-3597&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1558-3597&client=summon |