Designing exercise clinical trials for older adults with cancer: Recommendations from 2015 Cancer and Aging Research Group NCI U13 Meeting

Cancer and its treatment can lead to a myriad of adverse events and negatively impact quality of life of older cancer patients and survivors. Unmet physical activity needs vary across the cancer continuum and remain an important yet understudied area of research in this population. Exercise interven...

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Bibliographic Details
Published in:Journal of geriatric oncology Vol. 7; no. 4; pp. 293 - 304
Main Authors: Kilari, Deepak, Soto-Perez-de-Celis, Enrique, Mohile, Supriya Gupta, Alibhai, Shabbir M.H., Presley, Carolyn J., Wildes, Tanya M., Klepin, Heidi D., Demark-Wahnefried, Wendy, Jatoi, Amina, Harrison, Robert, Won, Elizabeth, Mustian, Karen M.
Format: Journal Article
Language:English
Published: Netherlands Elsevier Ltd 01.07.2016
Subjects:
Age Factors
Aged
Cancer
Exercise
Geriatric recommendations
Geriatrics - methods
Geriatrics - trends
Health Knowledge, Attitudes, Practice
Hematology, Oncology, and Palliative Medicine
Humans
Internal Medicine
Male
Medical Oncology - methods
Medical Oncology - trends
Neoplasms - psychology
Neoplasms - therapy
Older patients
Outcome Assessment (Health Care)
Patient Selection
Quality of Life
Randomized Controlled Trials as Topic
Research Design
Older patients
Geriatric recommendations
Exercise
Cancer
ISSN:1879-4068, 1879-4076, 1879-4076
Online Access:Get full text
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Summary:Cancer and its treatment can lead to a myriad of adverse events and negatively impact quality of life of older cancer patients and survivors. Unmet physical activity needs vary across the cancer continuum and remain an important yet understudied area of research in this population. Exercise interventions have been shown to be effective in treating both the physical and psychological declines associated with cancer and its treatment, with a potential to improve cancer-related outcomes. Despite the current evidence, exercise is clearly underutilized due to several barriers and knowledge gaps in existing trials that include appropriate population identification, design, and outcome measures selection. The benefits of regular exercise in both the primary and secondary prevention of chronic conditions are well established in the non-cancer population. In older cancer patients and survivors, further research is needed before exercise gains widespread acceptance. The Cancer and Aging Research Group convened experts in exercise, aging and cancer to evaluate current scientific evidence and knowledge gaps in geriatric exercise oncology. This report summarizes these findings and provides future research directions.
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ISSN:1879-4068
1879-4076
1879-4076
DOI:10.1016/j.jgo.2016.04.007