Hemodynamics of Mechanical Circulatory Support

An increasing number of devices can provide mechanical circulatory support (MCS) to patients with acute hemodynamic compromise and chronic end-stage heart failure. These devices work by different pumping mechanisms, have various flow capacities, are inserted by different techniques, and have differe...

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Bibliographic Details
Published in:Journal of the American College of Cardiology Vol. 66; no. 23; p. 2663
Main Authors: Burkhoff, Daniel, Sayer, Gabriel, Doshi, Darshan, Uriel, Nir
Format: Journal Article
Language:English
Published: United States 15.12.2015
Subjects:
Assisted Circulation - instrumentation
Assisted Circulation - methods
Cardiac Output
Extracorporeal Membrane Oxygenation - methods
Heart Failure - diagnosis
Heart Failure - physiopathology
Heart Failure - surgery
Heart-Assist Devices
Hemodynamics
Humans
Treatment Outcome
cardiac output
cardiac index
ventricular assist devices
pulmonary capillary wedge pressure
extracorporeal circulatory membrane oxygenation
central venous pressure
ISSN:1558-3597, 1558-3597
Online Access:Get more information
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Summary:An increasing number of devices can provide mechanical circulatory support (MCS) to patients with acute hemodynamic compromise and chronic end-stage heart failure. These devices work by different pumping mechanisms, have various flow capacities, are inserted by different techniques, and have different sites from which blood is withdrawn and returned to the body. These factors result in different primary hemodynamic effects and secondary responses of the body. However, these are not generally taken into account when choosing a device for a particular patient or while managing a patient undergoing MCS. In this review, we discuss fundamental principles of cardiac, vascular, and pump mechanics and illustrate how they provide a broad foundation for understanding the complex interactions between the heart, vasculature, and device, and how they may help guide future research to improve patient outcomes.
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ISSN:1558-3597
1558-3597
DOI:10.1016/j.jacc.2015.10.017