COVID-19 related neuroimaging findings: A signal of thromboembolic complications and a strong prognostic marker of poor patient outcome
To investigate the incidence and spectrum of neuroimaging findings and their prognostic role in hospitalized COVID-19 patients in New York City. This is a retrospective cohort study of 3218 COVID-19 confirmed patients admitted to a major healthcare system (three hospitals) in New York City between M...
Saved in:
| Published in: | Journal of the neurological sciences Vol. 414; p. 116923 |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Netherlands
Elsevier B.V
15.07.2020
|
| Subjects: | |
| ISSN: | 0022-510X, 1878-5883, 1878-5883 |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | To investigate the incidence and spectrum of neuroimaging findings and their prognostic role in hospitalized COVID-19 patients in New York City.
This is a retrospective cohort study of 3218 COVID-19 confirmed patients admitted to a major healthcare system (three hospitals) in New York City between March 1, 2020 and April 13, 2020. Clinical data were extracted from electronic medical records, and particularly data of all neurological symptoms were extracted from the imaging reports. Four neuroradiologists evaluated all neuroimaging studies for acute neuroimaging findings related to COVID-19.
14.1% of admitted COVID-19 patients had neuroimaging and this accounted for only 5.5% of the total imaging studies. Acute stroke was the most common finding on neuro-imaging, seen in 92.5% of patients with positive neuro-imaging studies, and present in 1.1% of hospitalized COVID-19 patients. Patients with acute large ischemic and hemorrhagic stroke had much higher mortality risk adjusted for age, BMI and hypertension compared to those COVID-19 patients without neuroimaging. (Odds Ratio 6.02 by LR; Hazard Ratio 2.28 by CRR).
Our study demonstrates acute stroke is the most common neuroimaging finding among hospitalized COVID-19 patients. Detection of an acute stroke is a strong prognostic marker of poor outcome. Our study also highlights the fact there is limited use of neuroimaging in these patients due to multiple logistical constraints. |
|---|---|
| AbstractList | To investigate the incidence and spectrum of neuroimaging findings and their prognostic role in hospitalized COVID-19 patients in New York City.
This is a retrospective cohort study of 3218 COVID-19 confirmed patients admitted to a major healthcare system (three hospitals) in New York City between March 1, 2020 and April 13, 2020. Clinical data were extracted from electronic medical records, and particularly data of all neurological symptoms were extracted from the imaging reports. Four neuroradiologists evaluated all neuroimaging studies for acute neuroimaging findings related to COVID-19.
14.1% of admitted COVID-19 patients had neuroimaging and this accounted for only 5.5% of the total imaging studies. Acute stroke was the most common finding on neuro-imaging, seen in 92.5% of patients with positive neuro-imaging studies, and present in 1.1% of hospitalized COVID-19 patients. Patients with acute large ischemic and hemorrhagic stroke had much higher mortality risk adjusted for age, BMI and hypertension compared to those COVID-19 patients without neuroimaging. (Odds Ratio 6.02 by LR; Hazard Ratio 2.28 by CRR).
Our study demonstrates acute stroke is the most common neuroimaging finding among hospitalized COVID-19 patients. Detection of an acute stroke is a strong prognostic marker of poor outcome. Our study also highlights the fact there is limited use of neuroimaging in these patients due to multiple logistical constraints. To investigate the incidence and spectrum of neuroimaging findings and their prognostic role in hospitalized COVID-19 patients in New York City.OBJECTIVETo investigate the incidence and spectrum of neuroimaging findings and their prognostic role in hospitalized COVID-19 patients in New York City.This is a retrospective cohort study of 3218 COVID-19 confirmed patients admitted to a major healthcare system (three hospitals) in New York City between March 1, 2020 and April 13, 2020. Clinical data were extracted from electronic medical records, and particularly data of all neurological symptoms were extracted from the imaging reports. Four neuroradiologists evaluated all neuroimaging studies for acute neuroimaging findings related to COVID-19.METHODSThis is a retrospective cohort study of 3218 COVID-19 confirmed patients admitted to a major healthcare system (three hospitals) in New York City between March 1, 2020 and April 13, 2020. Clinical data were extracted from electronic medical records, and particularly data of all neurological symptoms were extracted from the imaging reports. Four neuroradiologists evaluated all neuroimaging studies for acute neuroimaging findings related to COVID-19.14.1% of admitted COVID-19 patients had neuroimaging and this accounted for only 5.5% of the total imaging studies. Acute stroke was the most common finding on neuro-imaging, seen in 92.5% of patients with positive neuro-imaging studies, and present in 1.1% of hospitalized COVID-19 patients. Patients with acute large ischemic and hemorrhagic stroke had much higher mortality risk adjusted for age, BMI and hypertension compared to those COVID-19 patients without neuroimaging. (Odds Ratio 6.02 by LR; Hazard Ratio 2.28 by CRR).RESULTS14.1% of admitted COVID-19 patients had neuroimaging and this accounted for only 5.5% of the total imaging studies. Acute stroke was the most common finding on neuro-imaging, seen in 92.5% of patients with positive neuro-imaging studies, and present in 1.1% of hospitalized COVID-19 patients. Patients with acute large ischemic and hemorrhagic stroke had much higher mortality risk adjusted for age, BMI and hypertension compared to those COVID-19 patients without neuroimaging. (Odds Ratio 6.02 by LR; Hazard Ratio 2.28 by CRR).Our study demonstrates acute stroke is the most common neuroimaging finding among hospitalized COVID-19 patients. Detection of an acute stroke is a strong prognostic marker of poor outcome. Our study also highlights the fact there is limited use of neuroimaging in these patients due to multiple logistical constraints.CONCLUSIONSOur study demonstrates acute stroke is the most common neuroimaging finding among hospitalized COVID-19 patients. Detection of an acute stroke is a strong prognostic marker of poor outcome. Our study also highlights the fact there is limited use of neuroimaging in these patients due to multiple logistical constraints. AbstractObjectiveTo investigate the incidence and spectrum of neuroimaging findings and their prognostic role in hospitalized COVID-19 patients in New York City. MethodsThis is a retrospective cohort study of 3218 COVID-19 confirmed patients admitted to a major healthcare system (three hospitals) in New York City between March 1, 2020 and April 13, 2020. Clinical data were extracted from electronic medical records, and particularly data of all neurological symptoms were extracted from the imaging reports. Four neuroradiologists evaluated all neuroimaging studies for acute neuroimaging findings related to COVID-19. Results14.1% of admitted COVID-19 patients had neuroimaging and this accounted for only 5.5% of the total imaging studies. Acute stroke was the most common finding on neuro-imaging, seen in 92.5% of patients with positive neuro-imaging studies, and present in 1.1% of hospitalized COVID-19 patients. Patients with acute large ischemic and hemorrhagic stroke had much higher mortality risk adjusted for age, BMI and hypertension compared to those COVID-19 patients without neuroimaging. (Odds Ratio 6.02 by LR; Hazard Ratio 2.28 by CRR). ConclusionsOur study demonstrates acute stroke is the most common neuroimaging finding among hospitalized COVID-19 patients. Detection of an acute stroke is a strong prognostic marker of poor outcome. Our study also highlights the fact there is limited use of neuroimaging in these patients due to multiple logistical constraints. |
| ArticleNumber | 116923 |
| Author | Jones, Simon Dogra, Siddhant Nguyen, Vinh Bilaloglu, Seda Horwtiz, Leora Jain, Rajan Hochman, Katherine Raz, Eytan Kennedy, Helena Galetta, Steven Young, Matthew |
| Author_xml | – sequence: 1 givenname: Rajan surname: Jain fullname: Jain, Rajan email: rajan.jain@nyulangone.org organization: Department of Radiology, New York University Langone Health, New York, NY, United States of America – sequence: 2 givenname: Matthew surname: Young fullname: Young, Matthew organization: Department of Radiology, New York University Langone Health, New York, NY, United States of America – sequence: 3 givenname: Siddhant surname: Dogra fullname: Dogra, Siddhant organization: Department of Radiology, New York University Langone Health, New York, NY, United States of America – sequence: 4 givenname: Helena surname: Kennedy fullname: Kennedy, Helena organization: Department of Radiology, New York University Langone Health, New York, NY, United States of America – sequence: 5 givenname: Vinh surname: Nguyen fullname: Nguyen, Vinh organization: Department of Radiology, New York University Langone Health, New York, NY, United States of America – sequence: 6 givenname: Simon surname: Jones fullname: Jones, Simon organization: Department of Population Health, New York University Langone Health, New York, NY, United States of America – sequence: 7 givenname: Seda surname: Bilaloglu fullname: Bilaloglu, Seda organization: Department of Population Health, New York University Langone Health, New York, NY, United States of America – sequence: 8 givenname: Katherine surname: Hochman fullname: Hochman, Katherine organization: Department of Medicine, New York University Langone Health, New York, NY, United States of America – sequence: 9 givenname: Eytan surname: Raz fullname: Raz, Eytan organization: Department of Radiology, New York University Langone Health, New York, NY, United States of America – sequence: 10 givenname: Steven surname: Galetta fullname: Galetta, Steven organization: Department of Neurology, New York University Langone Health, New York, NY, United States of America – sequence: 11 givenname: Leora surname: Horwtiz fullname: Horwtiz, Leora organization: Department of Medicine, New York University Langone Health, New York, NY, United States of America |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32447193$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkttu1DAQhi1URLeFB-AG-ZKbLD4kTgJSpWo5VarUCw7izvI6k623iR1sp1KfgNdmli0VVKJcWCMr__ePM_8ckQMfPBDynLMlZ1y92i63Pi0FE3jnqhXyEVnwpm6KqmnkAVkwJkRRcfbtkByltGWMqaZpn5BDKcqy5q1ckB-ri69nbwve0giDydBRD3MMbjQb5ze0d77Dml7TU5rcxpuBhp7myxjGdQA8g7PUhnHCarILPlHjO2poyjEgP8Ww8SFlVI0mXkHc4VMIkU4oB59pmDPy8JQ87s2Q4NltPSZf3r_7vPpYnF98OFudnhe2qlQuWtFYA63hZdmvhe1sW6m6lH1leytk3SnDatNYLhQYVZZdB61VQvSNkLKpK5DH5GTvO83rETqLT4hm0FPEP443Ohin__7i3aXehGtdC6mUqtHg5a1BDN9nSFmPLlkYBuMhzEmLkqmqZqwSKH3xZ6-7Jr-njwK-F9gYUorQ30k407uE9VZjwnqXsN4njEx9j7Eu_xo9PtcND5Jv9iTgfK8dRJ0sRmChcxFs1l1wD9In92g7OI-pD1dwA2kb5ojbkTTXSWimP-12b7d6gkkmFCvRoP23wX-a_wRriesN |
| CitedBy_id | crossref_primary_10_3389_fneur_2021_711026 crossref_primary_10_1007_s11940_023_00747_6 crossref_primary_10_1186_s12879_021_06185_6 crossref_primary_10_3389_fmolb_2021_627723 crossref_primary_10_3390_neurolint13010010 crossref_primary_10_1016_j_jstrokecerebrovasdis_2020_104984 crossref_primary_10_1161_STROKEAHA_121_038056 crossref_primary_10_3171_CASE21160 crossref_primary_10_12688_f1000research_27971_1 crossref_primary_10_1007_s00415_020_10285_9 crossref_primary_10_3389_fneur_2021_664599 crossref_primary_10_1111_jon_12790 crossref_primary_10_17826_cumj_1133013 crossref_primary_10_1007_s40134_021_00379_1 crossref_primary_10_4103_0028_3886_314531 crossref_primary_10_1007_s13365_020_00903_7 crossref_primary_10_1016_j_jstrokecerebrovasdis_2020_105549 crossref_primary_10_1007_s42399_020_00388_9 crossref_primary_10_3389_fendo_2020_583006 crossref_primary_10_1007_s00259_021_05375_3 crossref_primary_10_1155_2021_2013371 crossref_primary_10_17116_jnevro2024124041159 crossref_primary_10_1016_j_radcr_2021_01_025 crossref_primary_10_1161_STROKEAHA_120_031786 crossref_primary_10_1097_CCM_0000000000004895 crossref_primary_10_1097_WNO_0000000000001454 crossref_primary_10_1186_s41983_021_00322_3 crossref_primary_10_1016_j_ejrad_2020_109393 crossref_primary_10_1016_j_rx_2021_03_005 crossref_primary_10_12688_f1000research_42308_1 crossref_primary_10_1007_s11239_020_02288_0 crossref_primary_10_1016_j_wneu_2020_06_220 crossref_primary_10_1007_s10072_020_04946_w crossref_primary_10_1016_j_wneu_2021_06_004 crossref_primary_10_3389_fcvm_2021_819318 crossref_primary_10_1016_j_jstrokecerebrovasdis_2022_106591 crossref_primary_10_1016_j_thromres_2020_08_017 crossref_primary_10_1002_ana_26076 crossref_primary_10_1055_a_1522_3155 crossref_primary_10_1007_s00415_020_09978_y crossref_primary_10_1016_j_jstrokecerebrovasdis_2021_105863 crossref_primary_10_1016_j_acra_2020_08_026 crossref_primary_10_1148_rg_2020200195 crossref_primary_10_1259_bjr_20210149 crossref_primary_10_1067_j_cpradiol_2021_06_015 crossref_primary_10_3390_brainsci10110845 crossref_primary_10_7759_cureus_19200 crossref_primary_10_1212_WNL_0000000000013184 crossref_primary_10_1177_25166085241262574 crossref_primary_10_1371_journal_pone_0282045 crossref_primary_10_1111_jon_12819 crossref_primary_10_1007_s10072_020_04801_y crossref_primary_10_1002_alz_12255 crossref_primary_10_1093_psyrad_kkab019 crossref_primary_10_3390_cells9112360 crossref_primary_10_1001_jama_2024_1059 crossref_primary_10_1111_bpa_13013 crossref_primary_10_3389_fpsyt_2021_765106 crossref_primary_10_1007_s11055_021_01144_9 crossref_primary_10_1007_s00415_021_10425_9 crossref_primary_10_3389_fneur_2020_579070 crossref_primary_10_1016_j_jstrokecerebrovasdis_2021_105881 crossref_primary_10_1161_STROKEAHA_120_032711 crossref_primary_10_1080_21681163_2022_2144762 crossref_primary_10_1111_ene_15072 crossref_primary_10_1007_s11920_021_01237_9 crossref_primary_10_2174_0929867329666220701124945 crossref_primary_10_1007_s12028_021_01297_y crossref_primary_10_1186_s13054_022_04080_3 crossref_primary_10_1177_1756286420978004 crossref_primary_10_1016_j_clinimag_2021_08_003 crossref_primary_10_1177_15910199211035302 crossref_primary_10_1016_j_jns_2020_117085 crossref_primary_10_1016_j_clinimag_2020_08_029 crossref_primary_10_1007_s12035_020_02094_y crossref_primary_10_1016_j_crad_2020_09_002 crossref_primary_10_1016_j_brainresbull_2022_06_014 crossref_primary_10_1161_STROKEAHA_120_032328 crossref_primary_10_1002_acn3_51166 crossref_primary_10_1161_STROKEAHA_120_030940 crossref_primary_10_3389_fneur_2023_1338593 crossref_primary_10_1002_ana_25967 crossref_primary_10_1053_j_sult_2024_03_003 crossref_primary_10_1007_s00415_021_10406_y crossref_primary_10_1161_ATVBAHA_120_314513 crossref_primary_10_3389_fneur_2025_1486887 crossref_primary_10_3390_brainsci10121017 crossref_primary_10_1055_s_0043_1768060 crossref_primary_10_1007_s42399_020_00598_1 crossref_primary_10_1016_j_nic_2022_07_003 crossref_primary_10_1111_ene_15008 crossref_primary_10_3389_fnagi_2021_827273 crossref_primary_10_7759_cureus_28633 crossref_primary_10_1007_s12028_021_01359_1 crossref_primary_10_1016_j_neulet_2020_135564 crossref_primary_10_1111_ene_15493 crossref_primary_10_1038_s41598_021_85906_y crossref_primary_10_7759_cureus_67644 crossref_primary_10_1016_j_wneu_2020_11_166 crossref_primary_10_1007_s12035_021_02347_4 crossref_primary_10_1016_j_rxeng_2021_03_004 |
| Cites_doi | 10.1001/jamaneurol.2020.1127 10.1056/NEJMc2008597 10.12788/jhm.3167 10.33588/rn.7009.2020179 10.1056/NEJMc2009787 10.2119/molmed.2009.00091 10.1056/NEJMc2014816 |
| ContentType | Journal Article |
| Copyright | 2020 Elsevier B.V. Copyright © 2020 Elsevier B.V. All rights reserved. 2020 Elsevier B.V. All rights reserved. 2020 Elsevier B.V. |
| Copyright_xml | – notice: 2020 Elsevier B.V. – notice: Copyright © 2020 Elsevier B.V. All rights reserved. – notice: 2020 Elsevier B.V. All rights reserved. 2020 Elsevier B.V. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 5PM |
| DOI | 10.1016/j.jns.2020.116923 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1878-5883 |
| EndPage | 116923 |
| ExternalDocumentID | PMC7236667 32447193 10_1016_j_jns_2020_116923 S0022510X20302604 1_s2_0_S0022510X20302604 |
| Genre | Multicenter Study Journal Article |
| GeographicLocations | New York City |
| GeographicLocations_xml | – name: New York City |
| GroupedDBID | --- --K --M .1- .FO .~1 0R~ 1B1 1P~ 1RT 1~. 1~5 4.4 457 4G. 53G 5GY 5RE 5VS 7-5 71M 8P~ 9JM AABNK AAEDT AAEDW AAIKJ AAKOC AALRI AAOAW AAQFI AATTM AAXKI AAXLA AAXUO AAYWO ABBQC ABCQJ ABFNM ABFRF ABGSF ABIVO ABJNI ABLJU ABMAC ABMZM ABTEW ABUDA ACDAQ ACGFO ACGFS ACIEU ACIUM ACLOT ACRLP ACVFH ADBBV ADCNI ADEZE ADUVX AEBSH AEFWE AEHWI AEIPS AEKER AENEX AEUPX AEVXI AFPUW AFRHN AFTJW AFXIZ AGHFR AGUBO AGWIK AGYEJ AHHHB AIEXJ AIIUN AIKHN AITUG AJRQY AJUYK AKBMS AKRWK AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ ANKPU ANZVX APXCP AXJTR BKOJK BLXMC BNPGV CS3 EBS EFJIC EFKBS EFLBG EO8 EO9 EP2 EP3 F5P FDB FIRID FNPLU FYGXN G-Q GBLVA IHE J1W KOM L7B LX8 M29 M2V M41 MO0 MOBAO N9A O-L O9- OAUVE OP~ OZT P-8 P-9 P2P PC. Q38 ROL RPZ SAE SCC SDF SDG SDP SEL SES SPCBC SSH SSN SSU SSZ T5K Z5R ~G- ~HD .55 .GJ 29L AACTN AAQXK ABWVN ABXDB ACRPL ADMUD ADNMO AFCTW AFJKZ AFKWA AGRDE AJOXV AKRLJ AMFUW ASPBG AVWKF AZFZN EJD FEDTE FGOYB G-2 HDW HMK HMO HMQ HVGLF HZ~ R2- RIG SEW SNS WUQ X7M ZGI ZXP AADPK AAIAV ABLVK ABYKQ DOVZS LCYCR ZA5 9DU AAYXX AGQPQ AIGII CITATION CGR CUY CVF ECM EIF NPM 7X8 5PM |
| ID | FETCH-LOGICAL-c556t-928cae9a144fb2cdc956743f5cfc237d6a07a8c126ea644dde9c622f8233875e3 |
| ISICitedReferencesCount | 124 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000540458100052&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 0022-510X 1878-5883 |
| IngestDate | Tue Sep 30 16:36:43 EDT 2025 Sun Sep 28 06:25:01 EDT 2025 Thu Apr 03 07:00:15 EDT 2025 Sat Nov 29 07:26:22 EST 2025 Tue Nov 18 22:11:29 EST 2025 Fri Feb 23 02:43:11 EST 2024 Tue Feb 25 20:00:48 EST 2025 Tue Oct 14 19:30:41 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Keywords | COVID-19 Neuro-imaging Stroke |
| Language | English |
| License | Copyright © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c556t-928cae9a144fb2cdc956743f5cfc237d6a07a8c126ea644dde9c622f8233875e3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://pubmed.ncbi.nlm.nih.gov/PMC7236667 |
| PMID | 32447193 |
| PQID | 2406570052 |
| PQPubID | 23479 |
| PageCount | 1 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_7236667 proquest_miscellaneous_2406570052 pubmed_primary_32447193 crossref_primary_10_1016_j_jns_2020_116923 crossref_citationtrail_10_1016_j_jns_2020_116923 elsevier_sciencedirect_doi_10_1016_j_jns_2020_116923 elsevier_clinicalkeyesjournals_1_s2_0_S0022510X20302604 elsevier_clinicalkey_doi_10_1016_j_jns_2020_116923 |
| PublicationCentury | 2000 |
| PublicationDate | 2020-07-15 |
| PublicationDateYYYYMMDD | 2020-07-15 |
| PublicationDate_xml | – month: 07 year: 2020 text: 2020-07-15 day: 15 |
| PublicationDecade | 2020 |
| PublicationPlace | Netherlands |
| PublicationPlace_xml | – name: Netherlands |
| PublicationTitle | Journal of the neurological sciences |
| PublicationTitleAlternate | J Neurol Sci |
| PublicationYear | 2020 |
| Publisher | Elsevier B.V |
| Publisher_xml | – name: Elsevier B.V |
| References | Oxley, Mocco, Majidi, Kellner, Shoirah, Singh, De Leacy, Shigematsu, Ladner, Yaeger, Skliut, Weinberger, Dangayach, Bederson, Tuhrim, Fifi (bb0035) 2020 Apr 28 HCUP Clinical Classifications Software (CCS). Healthcare Cost and Utilization Project (HCUP). August 2006. U.S. Agency for Healthcare Research and Quality, Rockville, MD. www.hcup-us.ahrq.gov/toolssoftware/ccs/ccs.jsp. Herman, Mayer, Sarwal (bb0015) 2020 Apr; 28 Mao, Jin, Wang, Hu, Chen, He, Chang, Hong, Zhou, Wang, Miao, Li, Hu (bb0005) 2020 Apr 10 Helms, Kremer, Merdji (bb0010) 2020 Chow, McWilliams, Kaplan, Stephens (bb0060) 2019 Jul 1; 14 Carod-Artal (bb0020) 2020 may 1; 70 Klok, Kruip, van der Meer, Arbous, DAMPJ, Kant, FHJ, van Paassen, MAM, Huisman, Endeman (bb0030) 2020 Apr 10 Centers for Disease Control and Prevention. Interim Guidelines for Collecting, Handling, and Testing Clinical Specimens from Persons for Coronavirus Disease 2019 (COVID-19). Accessed at on 27 March 2020. [Ref list]. Milbrandt, Reade, Lee (bb0025) 2009; 15 Kansagra, Goyal, Hamilton, Albers (bb0055) 2020 May 8 Zhou (bb0040) 9 March 2020 Carod-Artal (10.1016/j.jns.2020.116923_bb0020) 2020; 70 Helms (10.1016/j.jns.2020.116923_bb0010) 2020 Herman (10.1016/j.jns.2020.116923_bb0015) 2020; 28 Zhou (10.1016/j.jns.2020.116923_bb0040) Milbrandt (10.1016/j.jns.2020.116923_bb0025) 2009; 15 10.1016/j.jns.2020.116923_bb0050 Klok (10.1016/j.jns.2020.116923_bb0030) 2020 Chow (10.1016/j.jns.2020.116923_bb0060) 2019; 14 Oxley (10.1016/j.jns.2020.116923_bb0035) 2020 10.1016/j.jns.2020.116923_bb0045 Kansagra (10.1016/j.jns.2020.116923_bb0055) 2020 Mao (10.1016/j.jns.2020.116923_bb0005) 2020 |
| References_xml | – year: 2020 Apr 10 ident: bb0005 article-title: Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan publication-title: China. JAMA Neurol. – year: 2020 Apr 10 ident: bb0030 article-title: Incidence of thrombotic complications in critically ill ICU patients with COVID-19 publication-title: Thromb. Res. – year: 9 March 2020 ident: bb0040 article-title: Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study – reference: Centers for Disease Control and Prevention. Interim Guidelines for Collecting, Handling, and Testing Clinical Specimens from Persons for Coronavirus Disease 2019 (COVID-19). Accessed at – year: 2020 Apr 28 ident: bb0035 article-title: Large-vessel stroke as a presenting feature of Covid-19 in the young publication-title: N. Engl. J. Med. – volume: 15 start-page: 438 year: 2009 end-page: 445 ident: bb0025 article-title: Prevalence and significance of coagulation abnormalities in community-acquired pneumonia publication-title: Mol. Med. – reference: . on 27 March 2020. [Ref list]. – volume: 70 start-page: 311 year: 2020 may 1 end-page: 322 ident: bb0020 article-title: Neurological complications of coronavirus and COVID-19 publication-title: Rev. Neurol. – volume: 28 year: 2020 Apr ident: bb0015 article-title: Scoping review of prevalence of neurologic comorbidities in patients hospitalized for COVID-19 publication-title: Neurology – volume: 14 start-page: 441 year: 2019 Jul 1 end-page: 444 ident: bb0060 article-title: Things we do for no reason: neuroimaging for hospitalized patients with delirium publication-title: J. Hosp. Med. – year: 2020 ident: bb0010 article-title: Neurologic features in severe SARS-CoV-2 infection publication-title: N. Engl. J. Med. – reference: HCUP Clinical Classifications Software (CCS). Healthcare Cost and Utilization Project (HCUP). August 2006. U.S. Agency for Healthcare Research and Quality, Rockville, MD. www.hcup-us.ahrq.gov/toolssoftware/ccs/ccs.jsp. – year: 2020 May 8 ident: bb0055 article-title: Collateral Effect of Covid-19 on Stroke Evaluation in the United States publication-title: N. Engl. J. Med. – year: 2020 ident: 10.1016/j.jns.2020.116923_bb0005 article-title: Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan publication-title: China. JAMA Neurol. doi: 10.1001/jamaneurol.2020.1127 – ident: 10.1016/j.jns.2020.116923_bb0040 – ident: 10.1016/j.jns.2020.116923_bb0050 – volume: 28 year: 2020 ident: 10.1016/j.jns.2020.116923_bb0015 article-title: Scoping review of prevalence of neurologic comorbidities in patients hospitalized for COVID-19 publication-title: Neurology – year: 2020 ident: 10.1016/j.jns.2020.116923_bb0010 article-title: Neurologic features in severe SARS-CoV-2 infection publication-title: N. Engl. J. Med. doi: 10.1056/NEJMc2008597 – volume: 14 start-page: 441 issue: 7 year: 2019 ident: 10.1016/j.jns.2020.116923_bb0060 article-title: Things we do for no reason: neuroimaging for hospitalized patients with delirium publication-title: J. Hosp. Med. doi: 10.12788/jhm.3167 – year: 2020 ident: 10.1016/j.jns.2020.116923_bb0030 article-title: Incidence of thrombotic complications in critically ill ICU patients with COVID-19 publication-title: Thromb. Res. – volume: 70 start-page: 311 issue: 9 year: 2020 ident: 10.1016/j.jns.2020.116923_bb0020 article-title: Neurological complications of coronavirus and COVID-19 publication-title: Rev. Neurol. doi: 10.33588/rn.7009.2020179 – year: 2020 ident: 10.1016/j.jns.2020.116923_bb0035 article-title: Large-vessel stroke as a presenting feature of Covid-19 in the young publication-title: N. Engl. J. Med. doi: 10.1056/NEJMc2009787 – volume: 15 start-page: 438 year: 2009 ident: 10.1016/j.jns.2020.116923_bb0025 article-title: Prevalence and significance of coagulation abnormalities in community-acquired pneumonia publication-title: Mol. Med. doi: 10.2119/molmed.2009.00091 – ident: 10.1016/j.jns.2020.116923_bb0045 – year: 2020 ident: 10.1016/j.jns.2020.116923_bb0055 article-title: Collateral Effect of Covid-19 on Stroke Evaluation in the United States publication-title: N. Engl. J. Med. doi: 10.1056/NEJMc2014816 |
| SSID | ssj0006889 |
| Score | 2.6283753 |
| Snippet | To investigate the incidence and spectrum of neuroimaging findings and their prognostic role in hospitalized COVID-19 patients in New York City.
This is a... AbstractObjectiveTo investigate the incidence and spectrum of neuroimaging findings and their prognostic role in hospitalized COVID-19 patients in New York... To investigate the incidence and spectrum of neuroimaging findings and their prognostic role in hospitalized COVID-19 patients in New York City.OBJECTIVETo... |
| SourceID | pubmedcentral proquest pubmed crossref elsevier |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 116923 |
| SubjectTerms | Acute Disease Adolescent Adult Aged Aged, 80 and over Betacoronavirus Brain Ischemia - diagnostic imaging Brain Ischemia - epidemiology Brain Ischemia - etiology Cerebral Hemorrhage - diagnostic imaging Cerebral Hemorrhage - epidemiology Cerebral Hemorrhage - etiology Child Child, Preschool Comorbidity Coronavirus Infections - complications Coronavirus Infections - epidemiology COVID-19 Female Hospitals, Urban - statistics & numerical data Humans Hypertension - epidemiology Infant Infant, Newborn Inpatients Male Middle Aged Neuro-imaging Neuroimaging Neurology New York City - epidemiology Obesity - epidemiology Pandemics Pneumonia, Viral - complications Pneumonia, Viral - epidemiology Procedures and Techniques Utilization Prognosis Retrospective Studies SARS-CoV-2 Stroke Stroke - diagnostic imaging Stroke - epidemiology Stroke - etiology Tertiary Care Centers - statistics & numerical data Young Adult |
| Title | COVID-19 related neuroimaging findings: A signal of thromboembolic complications and a strong prognostic marker of poor patient outcome |
| URI | https://www.clinicalkey.com/#!/content/1-s2.0-S0022510X20302604 https://www.clinicalkey.es/playcontent/1-s2.0-S0022510X20302604 https://dx.doi.org/10.1016/j.jns.2020.116923 https://www.ncbi.nlm.nih.gov/pubmed/32447193 https://www.proquest.com/docview/2406570052 https://pubmed.ncbi.nlm.nih.gov/PMC7236667 |
| Volume | 414 |
| WOSCitedRecordID | wos000540458100052&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVESC databaseName: Elsevier SD Freedom Collection Journals 2021 customDbUrl: eissn: 1878-5883 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0006889 issn: 0022-510X databaseCode: AIEXJ dateStart: 19950101 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1bb9MwFLZ2QYgXxJ1ymYzEEygocRIn5q0aQwyJgdBAfbOcxGGt1qTqZdo_4P_wCzknttOkY4M9oKpRldqum_PlXOJzPhPykhVxBi8sjoliL2I68bIiYB4PiygrkjLkWjWbTSRHR-loJL5sbf1ytTBnp0lVpefnYvZfRQ3nQNhYOnsNcbeDwgn4DEKHI4gdjv8k-P3P3w_feYEwZSq4uo_8G-Op2Y6oWaOufixMRTpmbxhvFLdLmGa1hjfSXvczzRtCVywrqZvS9RqT85DodYq5Pc0yw6yu546j9XW9WuYbJAgdvxc93WZKTutaI7zOZVSG1-Crmqyh22olu0F564BjelnzCHdcFCdqncXTsSCNaVXd5xsQzCJrZdzV2RguB_6oq7OjIOpo3SDgwlQtXzAI5tnE5M2kQm52hibCte2Tb28YxTZV0WXBTSQMIXEIaYbYJrssiQUYg93h4cHoY2v_eZoKx1GP83Zr6U1W4cY8LvOGLkY7m0m7HS_o-A65bcVIhwZ2d8mWru6Rm59sgsZ98tOhj1r00S76qEPfWzqkBnu0Lmkfe7SHPQrYo4oa7NE19qjBHnZH7FGLPWqx94B8e39wvP_Bs3t9eHkc86UnWJorLRTE92XG8iKHuB2c2zLOy5yFScGVn6g0DxjoDnDhwSiLnDNWpiwMIeTW4UOyU9WVfkxoHsCJMku0hhGELgVnShShzwoRxcrPBsR311zmlggf92M5lZfKekBetV1mhgXmqsbMCVK68mYwyBIgeVWn5E-d9MJqloUM5IJJX2J2BUNYMTDPjPvRgERtT3vDGm_4bz_4wmFMgkXBZUJV6XoFjcDHx10vYjYgjwzm2j8N4Rd4swKn20Nj2wDZ6vvfVOOThrU-YSHnPHlynUv5lNxaq4RnZGc5X-nn5EZ-thwv5ntkOxmle_b2-w0VZhCs |
| linkProvider | Elsevier |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=COVID-19+related+neuroimaging+findings%3A+A+signal+of+thromboembolic+complications+and+a+strong+prognostic+marker+of+poor+patient+outcome&rft.jtitle=Journal+of+the+neurological+sciences&rft.au=Jain%2C+Rajan&rft.au=Young%2C+Matthew&rft.au=Dogra%2C+Siddhant&rft.au=Kennedy%2C+Helena&rft.date=2020-07-15&rft.issn=0022-510X&rft.volume=414&rft.spage=116923&rft_id=info:doi/10.1016%2Fj.jns.2020.116923&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_jns_2020_116923 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0022-510X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0022-510X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0022-510X&client=summon |