The association of AGTR2 polymorphisms with preeclampsia and uterine artery bilateral notching is modulated by maternal BMI

This study aimed to determine the association of AGTR1 and AGTR2 polymorphisms with preeclampsia and whether these are affected by environmental factors and fetal sex. Overall 3234 healthy nulliparous women, their partners and babies were recruited prospectively to the SCOPE study in Adelaide and Au...

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Bibliographic Details
Published in:	Placenta (Eastbourne) Vol. 34; no. 1; pp. 75 - 81
Main Authors:	Zhou, A., Dekker, G.A., Lumbers, E.R., Lee, S.Y., Thompson, S.D., McCowan, L.M.E., Roberts, C.T.
Format:	Journal Article
Language:	English
Published:	Kidlington Elsevier Ltd 01.01.2013 Elsevier
Subjects:	Adult AGTR2 A1675G AGTR2 C4599A Biological and medical sciences BMI Body Mass Index Case-Control Studies Embryology: invertebrates and vertebrates. Teratology Female Fundamental and applied biological sciences. Psychology Gene-Environment Interaction Genetic Association Studies Genetic Predisposition to Disease Humans Infant, Newborn Internal Medicine Male Mothers - statistics & numerical data Obstetrics and Gynecology Polymorphism Polymorphism, Single Nucleotide Pre-Eclampsia - epidemiology Pre-Eclampsia - genetics Preeclampsia Pregnancy Pregnancy Complications, Cardiovascular - epidemiology Pregnancy Complications, Cardiovascular - genetics Receptor, Angiotensin, Type 2 - genetics Receptor, Angiotensin, Type 2 - metabolism Uterine Artery - pathology Uterine artery bilateral notching Uterine Diseases - epidemiology Uterine Diseases - genetics Young Adult sBP AGTR2 A1675G dBP RAS SCOPE AGTR2 C4599A Preeclampsia Uterine artery bilateral notching AGTR2 Polymorphism BMI SCreening f Or Pregnancy Endpoints body mass index renin angiotensin system systolic blood pressure angiotensin II type II receptor diastolic blood pressure Body mass index Vertebrata Mammalia Pregnancy disorders Mother Blood vessel Bilateral Circulatory system Uterine artery Pregnancy toxemia
ISSN:	0143-4004, 1532-3102, 1532-3102
Online Access:	Get full text
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