Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study
Metabolic syndrome is characterized by cardiometabolic risk factors that include obesity, insulin resistance, hypertension and dyslipidemia. Oxidative stress is known to play a major role in the pathogenesis of metabolic syndrome. The objective of this study was to examine the effectiveness of hydro...
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| Published in: | Journal of clinical biochemistry and nutrition Vol. 46; no. 2; p. 140 |
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| Format: | Journal Article |
| Language: | English |
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| ISSN: | 1880-5086, 1880-5086 |
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| Abstract | Metabolic syndrome is characterized by cardiometabolic risk factors that include obesity, insulin resistance, hypertension and dyslipidemia. Oxidative stress is known to play a major role in the pathogenesis of metabolic syndrome. The objective of this study was to examine the effectiveness of hydrogen rich water (1.5-2 L/day) in an open label, 8-week study on 20 subjects with potential metabolic syndrome. Hydrogen rich water was produced, by placing a metallic magnesium stick into drinking water (hydrogen concentration; 0.55-0.65 mM), by the following chemical reaction; Mg + 2H(2)O --> Mg (OH)(2) + H(2). The consumption of hydrogen rich water for 8 weeks resulted in a 39% increase (p<0.05) in antioxidant enzyme superoxide dismutase (SOD) and a 43% decrease (p<0.05) in thiobarbituric acid reactive substances (TBARS) in urine. Further, subjects demonstrated an 8% increase in high density lipoprotein (HDL)-cholesterol and a 13% decrease in total cholesterol/HDL-cholesterol from baseline to week 4. There was no change in fasting glucose levels during the 8 week study. In conclusion, drinking hydrogen rich water represents a potentially novel therapeutic and preventive strategy for metabolic syndrome. The portable magnesium stick was a safe, easy and effective method of delivering hydrogen rich water for daily consumption by participants in the study. |
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| AbstractList | Metabolic syndrome is characterized by cardiometabolic risk factors that include obesity, insulin resistance, hypertension and dyslipidemia. Oxidative stress is known to play a major role in the pathogenesis of metabolic syndrome. The objective of this study was to examine the effectiveness of hydrogen rich water (1.5-2 L/day) in an open label, 8-week study on 20 subjects with potential metabolic syndrome. Hydrogen rich water was produced, by placing a metallic magnesium stick into drinking water (hydrogen concentration; 0.55-0.65 mM), by the following chemical reaction; Mg + 2H(2)O --> Mg (OH)(2) + H(2). The consumption of hydrogen rich water for 8 weeks resulted in a 39% increase (p<0.05) in antioxidant enzyme superoxide dismutase (SOD) and a 43% decrease (p<0.05) in thiobarbituric acid reactive substances (TBARS) in urine. Further, subjects demonstrated an 8% increase in high density lipoprotein (HDL)-cholesterol and a 13% decrease in total cholesterol/HDL-cholesterol from baseline to week 4. There was no change in fasting glucose levels during the 8 week study. In conclusion, drinking hydrogen rich water represents a potentially novel therapeutic and preventive strategy for metabolic syndrome. The portable magnesium stick was a safe, easy and effective method of delivering hydrogen rich water for daily consumption by participants in the study. Metabolic syndrome is characterized by cardiometabolic risk factors that include obesity, insulin resistance, hypertension and dyslipidemia. Oxidative stress is known to play a major role in the pathogenesis of metabolic syndrome. The objective of this study was to examine the effectiveness of hydrogen rich water (1.5-2 L/day) in an open label, 8-week study on 20 subjects with potential metabolic syndrome. Hydrogen rich water was produced, by placing a metallic magnesium stick into drinking water (hydrogen concentration; 0.55-0.65 mM), by the following chemical reaction; Mg + 2H(2)O --> Mg (OH)(2) + H(2). The consumption of hydrogen rich water for 8 weeks resulted in a 39% increase (p<0.05) in antioxidant enzyme superoxide dismutase (SOD) and a 43% decrease (p<0.05) in thiobarbituric acid reactive substances (TBARS) in urine. Further, subjects demonstrated an 8% increase in high density lipoprotein (HDL)-cholesterol and a 13% decrease in total cholesterol/HDL-cholesterol from baseline to week 4. There was no change in fasting glucose levels during the 8 week study. In conclusion, drinking hydrogen rich water represents a potentially novel therapeutic and preventive strategy for metabolic syndrome. The portable magnesium stick was a safe, easy and effective method of delivering hydrogen rich water for daily consumption by participants in the study.Metabolic syndrome is characterized by cardiometabolic risk factors that include obesity, insulin resistance, hypertension and dyslipidemia. Oxidative stress is known to play a major role in the pathogenesis of metabolic syndrome. The objective of this study was to examine the effectiveness of hydrogen rich water (1.5-2 L/day) in an open label, 8-week study on 20 subjects with potential metabolic syndrome. Hydrogen rich water was produced, by placing a metallic magnesium stick into drinking water (hydrogen concentration; 0.55-0.65 mM), by the following chemical reaction; Mg + 2H(2)O --> Mg (OH)(2) + H(2). The consumption of hydrogen rich water for 8 weeks resulted in a 39% increase (p<0.05) in antioxidant enzyme superoxide dismutase (SOD) and a 43% decrease (p<0.05) in thiobarbituric acid reactive substances (TBARS) in urine. Further, subjects demonstrated an 8% increase in high density lipoprotein (HDL)-cholesterol and a 13% decrease in total cholesterol/HDL-cholesterol from baseline to week 4. There was no change in fasting glucose levels during the 8 week study. In conclusion, drinking hydrogen rich water represents a potentially novel therapeutic and preventive strategy for metabolic syndrome. The portable magnesium stick was a safe, easy and effective method of delivering hydrogen rich water for daily consumption by participants in the study. |
| Author | Evans, Malkanthi Nakao, Atsunori Sharma, Prachi Guthrie, Najla Toyoda, Yoshiya |
| Author_xml | – sequence: 1 givenname: Atsunori surname: Nakao fullname: Nakao, Atsunori organization: Heart, Lung and Esophageal Surgery Institute, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, 15213, USA – sequence: 2 givenname: Yoshiya surname: Toyoda fullname: Toyoda, Yoshiya – sequence: 3 givenname: Prachi surname: Sharma fullname: Sharma, Prachi – sequence: 4 givenname: Malkanthi surname: Evans fullname: Evans, Malkanthi – sequence: 5 givenname: Najla surname: Guthrie fullname: Guthrie, Najla |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/20216947$$D View this record in MEDLINE/PubMed |
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| References | 9921520 - Methods Mol Biol. 1998;108:107-10 4386763 - Proc Natl Acad Sci U S A. 1968 Oct;61(2):748-55 19083400 - Nutr Res. 2008 Mar;28(3):137-43 12134566 - Nutr Clin Care. 2002 May-Jun;5(3):115-23 17486089 - Nat Med. 2007 Jun;13(6):688-94 18996093 - Biochem Biophys Res Commun. 2008 Dec 26;377(4):1195-8 8287538 - Clin Chem. 1994 Jan;40(1):18-23 8230310 - J Toxicol Environ Health. 1993 Oct-Nov;40(2-3):391-404 11790215 - JAMA. 2002 Jan 16;287(3):356-9 12123763 - Cardiovasc Res. 2002 Aug 1;55(2):239-49 12796054 - Am J Respir Crit Care Med. 2003 Jun 15;167(12):1600-19 10191503 - Cell Biochem Funct. 1999 Mar;17(1):1-7 19907413 - Kidney Int. 2010 Jan;77(2):101-9 18706888 - Biochem Biophys Res Commun. 2008 Oct 24;375(3):346-50 14744958 - Circulation. 2004 Jan 27;109(3):433-8 19148645 - Cancer Chemother Pharmacol. 2009 Sep;64(4):753-61 12941775 - Diabetes. 2003 Sep;52(9):2346-52 1928205 - Am J Med. 1991 Sep 30;91(3C):14S-22S 9164834 - Biochem J. 1997 May 15;324 ( Pt 1):1-18 18727697 - Am J Transplant. 2008 Oct;8(10):2015-24 12218958 - Med Sci Monit. 2002 Sep;8(9):RA210-5 11113618 - Exp Gerontol. 2000 Dec;35(9-10):1405-17 18492970 - JAMA. 2008 May 21;299(19):2287-93 9180251 - Atherosclerosis. 1997 May;131(1):107-13 1593209 - J Lab Clin Med. 1992 Jun;119(6):598-620 15599400 - J Clin Invest. 2004 Dec;114(12):1752-61 11563810 - Crit Rev Clin Lab Sci. 2001 Aug;38(4):263-355 12909459 - Trends Immunol. 2003 Aug;24(8):449-55 15346644 - Free Radic Res. 2004 Jun;38(6):535-9 |
| References_xml | – reference: 19083400 - Nutr Res. 2008 Mar;28(3):137-43 – reference: 10191503 - Cell Biochem Funct. 1999 Mar;17(1):1-7 – reference: 18996093 - Biochem Biophys Res Commun. 2008 Dec 26;377(4):1195-8 – reference: 8287538 - Clin Chem. 1994 Jan;40(1):18-23 – reference: 12941775 - Diabetes. 2003 Sep;52(9):2346-52 – reference: 11113618 - Exp Gerontol. 2000 Dec;35(9-10):1405-17 – reference: 15346644 - Free Radic Res. 2004 Jun;38(6):535-9 – reference: 18727697 - Am J Transplant. 2008 Oct;8(10):2015-24 – reference: 17486089 - Nat Med. 2007 Jun;13(6):688-94 – reference: 12123763 - Cardiovasc Res. 2002 Aug 1;55(2):239-49 – reference: 9921520 - Methods Mol Biol. 1998;108:107-10 – reference: 9164834 - Biochem J. 1997 May 15;324 ( Pt 1):1-18 – reference: 12796054 - Am J Respir Crit Care Med. 2003 Jun 15;167(12):1600-19 – reference: 19148645 - Cancer Chemother Pharmacol. 2009 Sep;64(4):753-61 – reference: 12909459 - Trends Immunol. 2003 Aug;24(8):449-55 – reference: 19907413 - Kidney Int. 2010 Jan;77(2):101-9 – reference: 11563810 - Crit Rev Clin Lab Sci. 2001 Aug;38(4):263-355 – reference: 11790215 - JAMA. 2002 Jan 16;287(3):356-9 – reference: 15599400 - J Clin Invest. 2004 Dec;114(12):1752-61 – reference: 14744958 - Circulation. 2004 Jan 27;109(3):433-8 – reference: 1593209 - J Lab Clin Med. 1992 Jun;119(6):598-620 – reference: 12218958 - Med Sci Monit. 2002 Sep;8(9):RA210-5 – reference: 8230310 - J Toxicol Environ Health. 1993 Oct-Nov;40(2-3):391-404 – reference: 12134566 - Nutr Clin Care. 2002 May-Jun;5(3):115-23 – reference: 18706888 - Biochem Biophys Res Commun. 2008 Oct 24;375(3):346-50 – reference: 4386763 - Proc Natl Acad Sci U S A. 1968 Oct;61(2):748-55 – reference: 18492970 - JAMA. 2008 May 21;299(19):2287-93 – reference: 9180251 - Atherosclerosis. 1997 May;131(1):107-13 – reference: 1928205 - Am J Med. 1991 Sep 30;91(3C):14S-22S |
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| Title | Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study |
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