Pharmacokinetics of a combined oral contraceptive in obese and normal-weight women

This study was conducted to compare oral contraceptive (OC) pharmacokinetics (PK) in normal-weight [body mass index (BMI) 19.0–24.9] and obese (BMI 30.0–39.9) women. During the third week of the third cycle of OC use, we admitted 15 normal-weight and 15 obese women for collection of 12 venous specim...

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Vydáno v:	Contraception (Stoneham) Ročník 81; číslo 6; s. 474 - 480
Hlavní autoři:	Westhoff, Carolyn L., Torgal, Anupama H., Mayeda, Elizabeth R., Pike, Malcolm C., Stanczyk, Frank Z.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	New York, NY Elsevier Inc 01.06.2010 Elsevier
Témata:	Adult Biological and medical sciences Birth control BMI Body Mass Index Combined oral contraceptives Contraceptives, Oral, Combined - blood Contraceptives, Oral, Combined - pharmacokinetics Contraceptives, Oral, Combined - pharmacology Estradiol - blood Ethinyl Estradiol - blood Ethinyl Estradiol - pharmacokinetics Female Genital system. Reproduction Gynecology. Andrology. Obstetrics Half-Life Hormonal contraception Humans Levonorgestrel - blood Levonorgestrel - pharmacokinetics Medical sciences Menstrual Cycle - blood Metabolic diseases Obesity Obesity - blood Obesity - physiopathology Obstetrics and Gynecology Organ Size Ovarian Follicle - anatomy & histology Ovarian Follicle - diagnostic imaging Ovarian Follicle - drug effects Ovulation Inhibition - blood Ovulation Inhibition - drug effects Pharmacokinetics Pharmacology. Drug treatments Progesterone - blood Radioimmunoassay Ultrasonography Young Adult Obesity Pharmacokinetics Combined oral contraceptives BMI Ethinylestradiol Human Estrogen Nutrition disorder Levonorgestrel Oral administration Progestagen Female Contraceptive Woman Nutritional status
ISSN:	0010-7824, 1879-0518, 1879-0518
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