Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis

Zinc (Zn) is an essential micronutrient and cofactor for up to 10% of proteins in living organisms. During Zn limitation, specialized enzymes called metallochaperones are predicted to allocate Zn to specific metalloproteins. This function has been putatively assigned to G3E GTPase COG0523 proteins,...

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Vydané v:	Cell Ročník 185; číslo 12; s. 2148
Hlavní autori:	Weiss, Andy, Murdoch, Caitlin C, Edmonds, Katherine A, Jordan, Matthew R, Monteith, Andrew J, Perera, Yasiru R, Rodríguez Nassif, Aslin M, Petoletti, Amber M, Beavers, William N, Munneke, Matthew J, Drury, Sydney L, Krystofiak, Evan S, Thalluri, Kishore, Wu, Hongwei, Kruse, Angela R S, DiMarchi, Richard D, Caprioli, Richard M, Spraggins, Jeffrey M, Chazin, Walter J, Giedroc, David P, Skaar, Eric P
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 09.06.2022
Predmet:	Animals GTP Phosphohydrolases - metabolism Homeostasis Metallochaperones - metabolism Metalloendopeptidases - metabolism Metalloproteins - genetics Mice Zebrafish - metabolism Zinc - metabolism metalloprotein zf-C6H2 CBWD ZNG1 metallochaperone zinc finger GTPase zinc COG0523 METAP1
ISSN:	1097-4172, 1097-4172
On-line prístup:	Zistit podrobnosti o prístupe
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